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Risk factors associated with underweight in children aged one to two years: a longitudinal study
BackgroundUnderweight is a prevalent health issue in children. This study aimed to identify factors associated with underweight in children aged 1–2...
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SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study
A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate...
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Factors affecting decisions of an HMO Drug Exemptions Committee on individual patient requests for coverage of non-formulary drugs
BackgroundIn Israel, coverage of health needs is delivered by four health maintenance organizations (HMOs), which are budgeted by the government...
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Coronary periarteritis and pericarditis are rare but distinct manifestations of heart involvement in IgG4-related disease: a retrospective cohort study
BackgroundThe heart can be involved in immunoglobulin (Ig)-G4-related disease (IgG4-RD). This study aimed to summarize the clinical features and...
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The hospital emigration to another region in the light of the environmental, social and governance model in Italy during the period 2004-2021
The following article presents an analysis of the impact of the Environmental, Social and Governance-ESG determinants on Hospital Emigration to...
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Nonadherence to oral cancer chemotherapy in hepatocellular carcinoma: prevalence and predictive factors in Vietnam
PurposeStandard oral cancer chemotherapy (OCT) or targeted therapy (OTT) has expanded the treatment methods for hepatocellular carcinoma (HCC)....
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Willingness to receive mpox vaccine among men who have sex with men: a systematic review and meta-analysis
BackgroundSince May 2022, mpox outbreaks have been occurring in non-mpox endemic areas, with the main population affected being men who have sex with...
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Moving from idea to reality: The barriers and enablers to implementing Child and Family Hubs policy into practice in NSW, Australia
BackgroundAdverse childhood experiences can impact physical and mental health throughout the lifespan. To support families experiencing adversity and...
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TOTEM: a multi-cancer detection and localization approach using circulating tumor DNA methylation markers
BackgroundDetection of cancer and identification of tumor origin at an early stage improve the survival and prognosis of patients. Herein, we...
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Impact of acid and laser etching of enamel on microleakage in different adhesive systems
This study aimed to evaluate the microleakage of light-cured and self-cured adhesives on enamel surfaces selectively etched with Er, Cr: YSGG laser...
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Early colonic-preparation and salvage laparoscopic appendectomy (ECSLA)- innovative protocol for the management of magnets ingestion
BackgroundIngestion of magnets carries risks for significant morbidity. We propose a new protocol designed to reduce the need for surgery, shorten...
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Efficacy of iron supplementation on physical capacity in non-anaemic iron-deficient individuals: protocol for an individual patient data meta-analysis
BackgroundA deficiency in iron stores is associated with various adverse health complications, which, if left untreated, can progress to states of...
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Prompt closure versus gradual weaning of external ventricular drain for hydrocephalus following aneurysmal subarachnoid haemorrhage: a statistical analysis plan for the DRAIN randomised clinical trial
BackgroundInsertion of an external ventricular drain (EVD) is a first-line treatment of acute hydrocephalus caused by aneurysmal subarachnoid...
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Tumoral periprostatic adipose tissue exovesicles-derived miR-20a-5p regulates prostate cancer cell proliferation and inflammation through the RORA gene
BackgroundFrom the first steps of prostate cancer (PCa) initiation, tumours are in contact with the most-proximal adipose tissue called periprostatic...
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Theory of change for addressing sex and gender bias, invisibility and exclusion in Australian health and medical research, policy and practice
Sex and gender are inadequately considered in health and medical research, policy and practice, leading to preventable disparities in health and...
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A protocol for the formative evaluation of the implementation of patient-reported outcome measures in child and adolescent mental health services as part of a learning health system
BackgroundMental health conditions affect one in seven young people and research suggests that current mental health services are not meeting the...
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The challenges of assessing adiposity in a clinical setting
To tackle the burden of obesity-induced cardiometabolic disease, the scientific community relies on accurate and reproducible adiposity measurements...
