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Readiness for advance care planning and related factors in the general population: a cross sectional study in Iran
ContextAdvance Care Planning (ACP), as a process for expressing and recording patients' preferences about end-of-life care, has received increasing...
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Identifying SCS Trial Responders Immediately After Postoperative Programming with ECAP Dose-Controlled Closed-Loop Therapy
IntroductionDrawbacks of fixed-output spinal cord stimulation (SCS) screening trials may lead to compromised trial outcomes and poor predictability...
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Post-intensive care syndrome screening: a French multicentre survey
BackgroundPost-intensive care syndrome (PICS), defined as physical, cognitive, and mental-health symptoms persisting long after intensive-care-unit...
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Methadone versus other opioids for refractory malignant bone pain: a pilot randomised controlled study
PurposeRefractory cancer-induced bone pain (CIBP) affects a patient’s functional capacity and quality of life, but there is limited evidence to guide...
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Comparison of patient-controlled epidural analgesia and epidural morphine for post-cesarean section analgesia: experience from a tertiary center in China
PurposeTo compare patient-controlled epidural analgesia (PCEA) and epidural morphine (EM) for post-cesarean section analgesia in real-world...
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Radial artery catheterization using a novel T-type ultrasound probe: a single-center randomized study
Ultrasound guidance has been reported to facilitate radial artery catheterization compared with the palpation method. However, a recent meta-analysis...
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Neurobiology of Obsessive–Compulsive Disorder from Genes to Circuits: Insights from Animal Models
Obsessive-compulsive disorder (OCD) is a chronic, severe psychiatric disorder that has been ranked by the World Health Organization as one of the...
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Oral antivirals for COVID-19 among patients with cancer
PurposeImmunocompromised individuals, such as those diagnosed with cancer, are at a significantly higher risk for severe illness and mortality when...
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Children and adolescents with primary headaches exhibit altered sensory profiles – a multi-modal investigation
BackgroundPediatric headache is an increasing medical problem that has adverse effects on children’s quality of life, academic performance, and...
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The effect of BIS-guided anaesthesia on the incidence of postoperative nausea and vomiting in children: a prospective randomized double-blind study
BackgroundPostoperative nausea and vomiting (PONV) is a significant problem following paediatric surgery, and volatile anaesthetics are an important...
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Peripheral perfusion index as a predictor of reintubation in critically ill surgical patients
PurposeWe aimed to evaluate the ability of the peripheral perfusion index (PPI) to predict reintubation of critically ill surgical patients.
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Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Projecting to the Bed Nucleus of the Stria Terminalis Promote Wakefulness and Positive Affective State
The nucleus accumbens (NAc) plays an important role in various emotional and motivational behaviors that rely on heightened wakefulness. However, the...
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Strategies for DPYD testing prior to fluoropyrimidine chemotherapy in the US
PurposePatients with dihydropyrimidine dehydrogenase (DPD) deficiency are at high risk for severe and fatal toxicity from fluoropyrimidine (FP)...
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Predictive value of dynamic arterial elastance for vasopressor withdrawal: a systematic review and meta-analysis
BackgroundDynamic arterial elastance (Ea dyn ) has been investigated for its ability to predict hypotension during the weaning of vasopressors. Our...
