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Visualization of Blood–Brain Barrier Disruption in Septic Mice with the New Method Based on in Vivo Imaging Technology
BackgroundDynamic monitoring of the blood–brain barrier (BBB) functional status in septic mice can help to explore the pathological mechanisms....
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Nucleus Accumbens Corticotropin-Releasing Hormone Neurons Projecting to the Bed Nucleus of the Stria Terminalis Promote Wakefulness and Positive Affective State
The nucleus accumbens (NAc) plays an important role in various emotional and motivational behaviors that rely on heightened wakefulness. However, the...
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Urine output is an early and strong predictor of acute kidney injury and associated mortality: a systematic literature review of 50 clinical studies
BackgroundAlthough the present diagnosis of acute kidney injury (AKI) involves measurement of acute increases in serum creatinine (SC) and reduced...
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Peripheral perfusion index as a predictor of reintubation in critically ill surgical patients
PurposeWe aimed to evaluate the ability of the peripheral perfusion index (PPI) to predict reintubation of critically ill surgical patients.
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Predictive value of dynamic arterial elastance for vasopressor withdrawal: a systematic review and meta-analysis
BackgroundDynamic arterial elastance (Ea dyn ) has been investigated for its ability to predict hypotension during the weaning of vasopressors. Our...
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Physiological and clinical effects of trunk inclination adjustment in patients with respiratory failure: a sco** review and narrative synthesis
BackgroundAdjusting trunk inclination from a semi-recumbent position to a supine-flat position or vice versa in patients with respiratory failure...
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Effects of anesthesia with sevoflurane on outcome parameters in murine experimental studies
PurposeMultiple murine studies modelling the immuno-pathophysiological consequences of trauma, shock, burn or sepsis were performed during the last...
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Complications following surgical treatment of patella fractures - a systematic review and proportional meta-analysis
PurposeThe aim of this systematic review and proportional meta-analysis was to identify complications of surgical treatment of patella fractures and...
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Limited impact of traumatic brain injury on the post-traumatic inflammatory cellular response
PurposeTrauma triggers a systemic inflammatory cellular response due to tissue damage, potentially leading to a secondary immune deficiency. Trauma...
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Increasing plasma calprotectin (S100A8/A9) is associated with 12-month mortality and unfavourable functional outcome in critically ill COVID-19 patients
BackgroundCalprotectin (S100A8/A9) is a pro-inflammatory mediator primarily released from neutrophils. Previous studies have revealed associations...
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Exploring the effects of post operative hyperoxic intermittent stimuli on reticulocyte levels in cancer patients: a randomized controlled study
BackgroundAnemia is common among hospitalized critically ill and surgical oncological patients. The rising incidence of cancer and aggressive...
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Ventriculo-arterial (VA) coupling and fQRS as new selection criteria for primary prevention ICD placement
For decades, left ventricular ejection fraction (LVEF < 35%) has been a mainstay for identifying heart failure (HF) patients most likely to benefit...
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Impact of tracheostomy tube modalities on ventilatory mechanics: a bench study
PurposeTracheostomized patients often present with muscle weakness, altered consciousness, or swallowing difficulties. Hence, the literature is...
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Value-based preoperative assessment in a large academic hospital
BackgroundValue-based healthcare (VBHC) is an approach that focuses on delivering the highest possible value for patients while driving cost...
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Tourniquets
Purpose of ReviewTourniquets have a longstanding history in combat casualty care, but only became widely accepted in the last 20 years as effective...
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Effects of sodium-glucose transporter-2 inhibition on systemic hemodynamics, renal function, and intra-renal oxygenation in sepsis-associated acute kidney injury
BackgroundPeople with type 2 diabetes mellitus treated with sodium-glucose transporter-2 inhibitors (SGLT2i) have lower rates of acute kidney injury...
