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The utility of various predictive equations in patients with severe Obstructive Sleep Apnea: a clinical practice viewpoint in settings with limited resources
BackgroundThe continuous positive airway pressure (CPAP) needed for the treatment of obstructive sleep apnea (OSA) can be determined after a manual...
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Mechanical Thrombectomy for Acute Ischemic Stroke: Current State and Future Directions
Purpose of reviewThis review summarizes significant advancements in mechanical thrombectomy (MT) to treat acute ischemic stroke after the pivotal...
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Key performance indicators in pre-hospital response to disasters and mass casualty incidents: a sco** review
PurposeThe objective of this study was to offer a comprehensive synthesis of the existing Key performance indicators (KPIs) used in the evaluation of...
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Lower or higher oxygenation targets in the intensive care unit: an individual patient data meta-analysis
PurposeOptimal oxygenation targets for patients with acute hypoxemic respiratory failure in the intensive care unit (ICU) are not clearly defined due...
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Commentary on the “A multidisciplinary opioid-reduction pathway for robotic prostatectomy: outcomes at year one”
BackgroundOpioid-sparing multimodal analgesia is increasingly emphasized for postoperative pain management. This commentary discusses a study by...
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The paradox of workplace violence in the intensive care unit: a focus group study
BackgroundConflicts with patients and relatives occur frequently in intensive care units (ICUs), driven by factors that are intensified by critical...
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Burden of illness in patients with pulmonary hypertension due to interstitial lung disease: a real-world analysis
BackgroundPulmonary hypertension due to interstitial lung disease (PH-ILD) is associated with high rates of respiratory failure and death. Healthcare...
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Implications of sedation during the use of noninvasive ventilation in children with acute respiratory failure (SEDANIV Study)
BackgroundThe objective of this study was to analyze the effects of sedation administration on clinical parameters, comfort status, intubation...
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Relationship between epidural catheter migration beneath the skin and subcutaneous fat thickness assessed using postoperative CT imaging: a retrospective cross-sectional study
PurposeThe causes of epidural catheter migration beneath the skin have not been previously investigated. We hypothesized that greater subcutaneous...
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Incompatibility of the short-acting benzodiazepine remimazolam with common perioperative medication
BackgroundRemimazolam is a relatively new benzodiazepine with growing use in procedural sedation and general anaesthesia. Initiated by case reports,...
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The RNA helicases DDX19A/B modulate selinexor sensitivity by regulating MCL1 mRNA nuclear export in leukemia cells
Selinexor, a first-in-class exportin1 (XPO1) inhibitor, is an attractive anti-tumor agent because of its unique mechanisms of action; however, its...
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Fluid management for sepsis-induced hypotension in patients with advanced chronic kidney disease: a secondary analysis of the CLOVERS trial
BackgroundEarly fluid management in patients with advanced chronic kidney disease (CKD) and sepsis-induced hypotension is challenging with limited...
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Health-related quality of life and symptoms of chronic myeloid leukemia patients after discontinuation of tyrosine kinase inhibitors: results from the EURO-SKI Trial
Limited data is available on the health-related quality of life (HRQoL) and symptoms of patients with chronic myeloid leukemia (CML) who are in...