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The significance of the apelinergic system in doxorubicin-induced cardiotoxicity
Cancer is the leading cause of death worldwide, and the number of cancer-related deaths is expected to increase. Common types of cancer include skin,...
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Intentional coronary revascularization versus conservative therapy in patients after peripheral artery revascularization due to critical limb ischemia: the INCORPORATE trial
ObjectivesINCORPORATE trial was designed to evaluate whether default coronary-angiography (CA) and ischemia-targeted revascularization is superior...
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A phenome-wide association and factorial Mendelian randomization study on the repurposing of uric acid-lowering drugs for cardiovascular outcomes
Uric acid has been linked to various disease outcomes. However, it remains unclear whether uric acid-lowering therapy could be repurposed as a...
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Hypertrophic Cardiomyopathy: From Medical Treatment to Advanced Heart Failure Therapies
Purpose of ReviewThere has been much debate surrounding novel medical therapies and heart transplantation listing challenges in patients with...
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Incompatibility of the short-acting benzodiazepine remimazolam with common perioperative medication
BackgroundRemimazolam is a relatively new benzodiazepine with growing use in procedural sedation and general anaesthesia. Initiated by case reports,...
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Evaluation of the Protective Effects of Lugol’s Solution in Rats Poisoned with Aluminum Phosphide (Rice Tablets)
Aluminum phosphide (AlP) is the main component of rice tablets (a pesticide), which produces phosphine gas (PH3) when exposed to stomach acid. The...
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Relationship between epidural catheter migration beneath the skin and subcutaneous fat thickness assessed using postoperative CT imaging: a retrospective cross-sectional study
PurposeThe causes of epidural catheter migration beneath the skin have not been previously investigated. We hypothesized that greater subcutaneous...
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Off-pump Versus On-pump Coronary Artery Bypass Grafting in Diabetic patients: A Meta-analysis of Observational Studies with a Propensity-Score Analysis
PurposeThe debate between off-pump coronary artery bypass grafting (OPCAB) and on-pump coronary artery bypass grafting (ONCAB) in diabetic patients...
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89Zr-immunoPET-guided selection of a CD33xIL15 fusion protein optimized for antitumor immune cell activation and in vivo tumour retention in acute myeloid leukaemia
PurposeImmune cells are capable of eliminating leukemic cells, as evidenced by outcomes in hematopoietic cell transplantation (HCT). However,...
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Do-not-attempt-resuscitation decision making: physicians’ recommendations differ from the GO-FAR score predictions
Background and aimIn-hospital cardiac arrest (IHCA) is a major cause of mortality globally, and over 50% of the survivors will require institutional...
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Momelotinib versus Continued Ruxolitinib or Best Available Therapy in JAK Inhibitor-Experienced Patients with Myelofibrosis and Anemia: Subgroup Analysis of SIMPLIFY-2
IntroductionSome Janus kinase (JAK) inhibitors such as ruxolitinib and fedratinib do not address and may worsen anemia in patients with...
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Association between triglyceride glucose-waist height ratio index and cardiovascular disease in middle-aged and older Chinese individuals: a nationwide cohort study
BackgroundThe triglyceride-glucose (TyG) index and its combination with obesity indicators can predict cardiovascular diseases (CVD). However, there...
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Quantitative Digital Subtraction Angiography Measurement of Arterial Velocity at Low Radiation Dose Rates
PurposeQuantitative digital subtraction angiography (qDSA) has been proposed to quantify blood velocity for monitoring treatment progress during...
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The attenuated hepatic clearance of propionate increases cardiac oxidative stress in propionic acidemia
Propionic acidemia (PA), arising from PCCA or PCCB variants, manifests as life-threatening cardiomyopathy and arrhythmias, with unclear...
