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  1. Impedimetric Detection of DNA Hybridization: Towards Near-Patient DNA Diagnostics

    Immobilization strategies for the attachment of nucleotide probes to both microarrays and microfabricated interdigitated electrodes differ to...
    Anthony Guiseppi-Elie, Louise Lingerfelt in Immobilisation of DNA on Chips I
    Chapter

  2. Introduction

    Genetic algorithms (GAs) are powerful search techniques based on principles of evolution. They are now widely applied to solve problems in many...
    Ying-** Chen in Extending the Scalability of Linkage Learning Genetic Algorithms
    Chapter

  3. Linkage Learning Genetic Algorithm

    In order to handle linkage evolution and to tackle the ordering problem, Harik [47] took Holland’s call [53] for the evolution of tight linkage quite...
    Ying-** Chen in Extending the Scalability of Linkage Learning Genetic Algorithms
    Chapter

  4. Preliminaries: Assumptions and the Test Problem

    After introducing the background and motivation of the linkage learning genetic algorithm, we will start to improve and understand the linkage...
    Ying-** Chen in Extending the Scalability of Linkage Learning Genetic Algorithms
    Chapter

  6. Content Based Image Compression in Biomedical High-Throughput Screening Using Artificial Neural Networks

    Biomedical High-Throughput Screening (HTS) requires specific properties of image compression. Particularly especially when archiving a huge number of...
    Udo Seiffert in Bioinformatics Using Computational Intelligence Paradigms
    Chapter

  7. Discriminative Clustering of Yeast Stress Response

    When a yeast cell is challenged by a rapid change in the conditions, be it temperature, osmolarity, pH, nutrient or other, it starts a genome stress...
    Samuel Kaski, Janne Nikkilä, ... Christophe Roos in Bioinformatics Using Computational Intelligence Paradigms
    Chapter

  8. Medical Bioinformatics: Detecting Molecular Diseases with Case-Based Reasoning

    Based on the Human Genome Project, the new interdisciplinary subject of bioinformatics has become an important research topic during the last decade....
    Ralf Hofestädt, Thoralf Töpel in Bioinformatics Using Computational Intelligence Paradigms
    Chapter

  9. Immobilization of DNA on Microarrays

    Microarrays are new analytical devices that allow the parallel and simultaneous detection of thousands of target compounds. Microarrays, also...
    Christian Heise, Frank F. Bier in Immobilisation of DNA on Chips II
    Chapter

  10. Immobilization of Nucleic Acids Using Biotin-Strept(avidin) Systems

    There are several advantages for using biotin-streptavidin/avidin (strept(avi-din)) systems to immobilize nucleic acids and other molecules. These...
    Cassandra L. Smith, Jaqueline S. Milea, Giang H. Nguyen in Immobilisation of DNA on Chips II
    Chapter

  11. Immobilization of Oligonucleotides for Biochemical Sensing by Self-Assembled Monolayers: Thiol-Organic Bonding on Gold and Silanization on Silica Surfaces

    The covalent immobilization of biomolecules on surfaces is of great interest for many medical and bioanalytical applications. Currently, there is...
    F. Luderer, U. Walschus in Immobilisation of DNA on Chips I
    Chapter

  12. Analytical Ultracentrifuge for the Characterization of Detergent in Solution

    We have characterized the hydrodynamic behaviour in H 2 O and D2O of two detergents, dodecyl-β-D-maltoside...
    Andrés G. Salvay, Christine Ebel in Analytical Ultracentrifugation VIII
    Conference paper

  13. Analytical Ultracentrifugation Studies of the Influenza M2 Homotetramerization Equilibrium in Detergent Solutions

    Though much progress has been made in the field of membrane protein folding, there is still much to learn about the association of transmembrane...
    Amanda L. Stouffer, William F. DeGrado, James D. Lear in Analytical Ultracentrifugation VIII
    Conference paper

  14. Self-Association of Phosphorylase Kinase under Molecular Crowding Conditions

    Self-association of phosphorylase kinase (PhK) has been studied using analytical ultracentrifugation and dynamic light scattering under the...
    Natalia A. Chebotareva, Alexey V. Meremyanin, ... Boris I. Kurganov in Analytical Ultracentrifugation VIII
    Conference paper

  15. Molecular Properties and Electrostatic Interactions of Linear Poly(allylamine hydrochloride) Chains

    The efficiency of two azoinitiators in the polymerization of allylamine salts in water and organic solvents was studied comparatively....
    G.M. Pavlov, E.F. Panarin, ... N.N. Tarasova in Analytical Ultracentrifugation VIII
    Conference paper

  16. Oligomerization of Hydroperoxide Lyase, a Novel P450 Enzyme in Plants

    The oligomeric state of fatty acid hydroperoxide lyase (HPL), of molar mass ∼55 kDa is uncertain and it has been reported as a trimer or tetramer...
    Anuja Khan, Richard K. Hughes, ... Stephen E. Harding in Analytical Ultracentrifugation VIII
    Conference paper

  17. Aggregation of Dibutyl Phthalate Molecules in Decalin Solutions Evidenced by Hydrodynamic and Optical Measurements

    Hydrodynamic and optical investigations were performed on the binary dibutyl phthalate (DBP)-decalin liquid mixtures with the DBP content varying...
    Peter N. Lavrenko, Elena V. Belyaeva, ... Olga V. Okatova in Analytical Ultracentrifugation VIII
    Conference paper

  18. Ab initio and Constrained Modeling of Phosphorylase

    The joint use of small-angle X-ray scattering (SAXS) and hydrodynamic data permits biologically useful reconstructions of protein structures to be...
    Helmut Durchschlag, Peter Zipper, Angelika Krebs in Analytical Ultracentrifugation VIII
    Conference paper

  19. Transcriptome analysis in abiotic stress conditions in higher plants

    Drought, high salinity, and low temperature are major environmental factors that limit plant productivity. Plants respond and adapt to these stresses...
    Motoaki Seki, Ayako Kamei, ... Kazuo Shinozaki in Plant Responses to Abiotic Stress
    Chapter

  20. Signal transduction in plant cold acclimation

    Temperate plants respond to low temperature by activating a cold acclimation program leading to enhanced tolerance to freezing temperatures. This...
    Pekka Heino, E. Tapio Palva in Plant Responses to Abiotic Stress
    Chapter
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