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Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...
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Prediction of microvascular invasion in hepatocellular carcinoma patients with MRI radiomics based on susceptibility weighted imaging and T2-weighted imaging
BackgroundThe accurate identification of microvascular invasion (MVI) in patients with hepatocellular carcinoma (HCC) is of great clinical importance.
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Clinical Audit of Obstetric Hysterectomy in a Tertiary Care Centre: An Observational Retroprospective Study
Purpose of StudyThe purpose of this study is to analyse the profile and characteristics of patients who may undergo obstetric hysterectomy, to study...
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Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey
PurposeThis study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...
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Safety and Efficacy of Covered Self-Expandable Metallic Stent for Choledochojejunal Anastomotic Stricture: A Multi-Center Retrospective Cohort Study
BackgroundBenign choledochojejunal anastomotic stricture (CJS) is a complication of pancreaticoduodenectomy and choledochojejunostomy. Typically...
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Deep learning model based on endoscopic images predicting treatment response in locally advanced rectal cancer undergo neoadjuvant chemoradiotherapy: a multicenter study
PurposeNeoadjuvant chemoradiotherapy has been the standard practice for patients with locally advanced rectal cancer. However, the treatment response...
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Impact and effect of imaging referral guidelines on patients and radiology services: a systematic review
ObjectivesThe objective of this systematic review was to offer a comprehensive overview and explore the associated outcomes from imaging referral...
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Clinical Investigation into Survival Outcomes Among Stage IV Epithelial Ovarian Cancer Patients Receiving Curative Treatment: Indian Setting
ObjectiveCurrently, there is scanty data regarding patients specifically with stage IV epithelial ovarian cancer (EOC) as many reports combine...
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Neuroprotective and vasoprotective effects of herb pair of Zhiqiao-Danggui in ischemic stroke uncovered by LC-MS/MS-based metabolomics approach
Ischemic stroke is the most important cause of disability and death worldwide, but current treatments remain limited. Traditional Chinese medicine...
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The efficacy of early office hysteroscopy in preventing intrauterine adhesions after abortion: a randomized controlled trial
BackgroundIntrauterine adhesions (IUA) are a challenging clinical problem in reproductive infertility. The most common causes are intrauterine...
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Diagnostic Ability and Reproducibility of NICE 2017 Intrapartum Cardiotocography Interpretation Guidelines: A Prospective Observational Study
Purpose of StudyAssessment of accuracy, intra-observer and inter-observer and agreement for CTG interpretation utilizing NICE guidelines 2017.
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The impact of physical activity and exercise interventions on symptoms for women experiencing menopause: overview of reviews
BackgroundWomen experiencing problematic menopausal symptoms report lower health-related quality of life and greater healthcare use than women...
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Carbon-ion radiotherapy alone vs. standard dose photon radiation with carbon-ion radiotherapy boost for high-grade gliomas: a retrospective study
BackgroundThis study aimed to compare the survival outcome and side effects in patients with primary high-grade glioma (HGG) who received carbon ion...
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Hyponatremia Is Associated with Mortality in Acute Pancreatitis Patients
BackgroundDisorders of serum sodium are common among general patients and are associated with poor outcomes. The prognostic value of serum sodium...
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Statins for the Primary Prevention of Anthracycline Cardiotoxicity: A Comprehensive Review
Purpose of ReviewThe aim of this review is two-fold: (1) To examine the mechanisms by which statins may protect from anthracycline-induced...
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Total gonadotropin dose did not affect euploid blastocyst rates: an analysis of more than 19,000 oocytes
BackgroundTo evaluate whether increasing total gonadotropin (Gn) dose is associated with changes in euploid blastocyst rate in preimplantation...