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Comparative proteomics in tall fescue to reveal underlying mechanisms for improving Photosystem II thermotolerance during heat stress memory
BackgroundThe escalating impacts of global warming intensify the detrimental effects of heat stress on crop growth and yield. Among the earliest and...
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An investigation of the molecular characterization of the tripartite motif (TRIM) family and primary validation of TRIM31 in gastric cancer
Most TRIM family members characterized by the E3-ubiquitin ligases, participate in ubiquitination and tumorigenesis. While there is a dearth of a...
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Population structure and selection signal analysis of indigenous sheep from the southern edge of the Taklamakan Desert
Analyzing the genetic diversity and selection characteristics of sheep (Ovis aries) holds significant value in understanding their environmental...
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Understanding the responses of tillering to 2,4-D isooctyl ester in Setaria viridis L.
BackgroundGreen foxtail [ Setaria viridis (L.)] is one of the most abundant and troublesome annual grass weeds in alfalfa fields in Northeast China....
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Investigation of the Circular Transcriptome in Alzheimer’s Disease Brain
Circular RNAs (circRNAs) are a subclass of non-coding RNAs which have demonstrated potential as biomarkers for Alzheimer’s disease (AD). In this...
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Rapid evolution of promoters from germline-specifically expressed genes including transposon silencing factors
BackgroundThe piRNA pathway in animal gonads functions as an ‘RNA-based immune system’, serving to silence transposable elements and prevent...
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Integrated proteomic and metabolomic profiling reveals novel insights on the inflammation and immune response in HFpEF
BackgroundThe precise mechanisms leading to the development of heart failure with preserved ejection fraction (HFpEF) remain incompletely defined. In...
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Exploring the genetic basis of anthracnose resistance in Ethiopian sorghum through a genome-wide association study
BackgroundSorghum anthracnose is a major disease that hampers the productivity of the crop globally. The disease is caused by the hemibiotrophic...
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Identification, validation and candidate gene analysis of major QTL for Supernumerary spikelets in wheat
BackgroundThe number of spikelets per spike is a key trait that affects the yield of bread wheat ( Triticum aestivum L.). Identification of the QTL...
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Dietary restriction promote sperm remodeling in aged roosters based on transcriptome analysis
BackgroundThe breeder rooster has played a pivotal role in poultry production by providing high-quality semen. Typically, fertility peaks between 30...
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Benchmarking short and long read polishing tools for nanopore assemblies: achieving near-perfect genomes for outbreak isolates
BackgroundOxford Nanopore provides high throughput sequencing platforms able to reconstruct complete bacterial genomes with 99.95% accuracy. However,...
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Transcriptomic responses of Mediterranean sponges upon encounter with symbiont microbial consortia
BackgroundSponges (phylum Porifera) constantly interact with microbes. They graze on microbes from the water column by filter-feeding and they harbor...
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New advances in drug development for metabolic dysfunction-associated diseases and alcohol-associated liver disease
Metabolic disorders are currently threatening public health worldwide. Discovering new targets and develo** promising drugs will reduce the global...
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A single-sample workflow for joint metabolomic and proteomic analysis of clinical specimens
Understanding the interplay of the proteome and the metabolome helps to understand cellular regulation and response. To enable robust inferences from...
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Targeting protein interaction networks in mitochondrial dynamics for neurodegenerative diseases
Mitochondria, the powerhouse of eukaryotic cells, are the central organelle controlling energy metabolism and apoptosis. Based on metabolic needs,...
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Comparative Functional Characterization of nst1, nst2, and nst3 in Arabidopsis thaliana Uncovers Previously Unknown Functions in Diverse Developmental Pathways Beyond Secondary Wall Formation
The regulation of secondary cell wall formation in Arabidopsis thaliana has been extensively studied with NST1 , NST2 , and NST3 playing key roles in...
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Functional and evolutionary comparative analysis of the DIR gene family in Nicotiana tabacum L. and Solanum tuberosum L.
BackgroundThe dirigent ( DIR ) genes encode proteins that act as crucial regulators of plant lignin biosynthesis. In Solanaceae species, members of...
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Population genetic structure of Culex tritaeniorhynchus in different types of climatic zones in China
BackgroundCulex tritaeniorhynchus is widely distributed in China, from Hainan Island in the south to Heilongjiang in the north, covering tropical,...
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Unraveling the genomic secrets of Tritonibacter mobilis AK171: a plant growth-promoting bacterium isolated from Avicennia marina
The scarcity of freshwater resources resulting in a significant yield loss presents a pressing challenge in agriculture. To address this issue,...
