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Pain prevalence and pain relief in end-of-life care – a national registry study
BackgroundDespite pain control being a top priority in end-of-life care, pain continues to be a troublesome symptom and comprehensive data on pain...
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Impact of rehabilitation unit-based physical activity therapy versus symptomatic supportive treatment on older patients with advanced cancer: a non-randomized controlled study
ObjectivesRelatively few studies have investigated the effects of rehabilitation-based physical activity therapy as a treatment for older patients...
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Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey
PurposeThis study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...
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Association of oral mucositis induced by anthracycline-cyclophosphamide and subsequent docetaxel treatment for perioperative breast cancer
PurposeAnthracycline-cyclophosphamide followed by docetaxel-containing chemotherapy is effective for perioperative breast cancer treatment. However,...
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Midregional Proatrial Natriuretic Peptide (MRproANP) is associated with vertebral fractures and low bone density in patients with chronic obstructive pulmonary disease (COPD)
BackgroundPatients with COPD are often affected by loss of bone mineral density (BMD) and osteoporotic fractures. Natriuretic peptides (NP) are known...
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The evolving landscape of IL-10, IL-22 and IL-26 in pleurisy especially in tuberculous pleurisy
Pleurisy can be categorized as primary or secondary, arising from immunological, tumorous, or microbial conditions. It often results in lung...
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Consensus-building to improve implementation of NICE guidance on planning for end-of-life treatment and care: a mixed-methods study
BackgroundDespite the availability of guidance for the provision of good end-of-life care, there are significant variations across the UK in its...
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Differences in severity of chemotherapy-induced nausea and vomiting between neoadjuvant and adjuvant chemotherapy in patients with breast cancer: analysis of data from two prospective observational studies
PurposeWe assessed the differences in chemotherapy-induced nausea and vomiting (CINV) severity in patients with breast cancer, receiving neoadjuvant...
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Changes in skeletal muscle function during chemotherapy and related factors in patients with acute leukemia
IntroductionSkeletal muscle function is an important prognostically relevant indicator in patients with acute leukemia (AL), but skeletal dysfunction...
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Specialized expertise among healthcare professionals in palliative care - A sco** review
BackgroundThe generalist-plus-specialist palliative care model is endorsed worldwide. In the Netherlands, the competencies and profile of the...
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Patient attitudes and experiences towards exercise during oncological treatment. A qualitative systematic review
PurposeExercise and physical activity (PA) during oncological treatment have many benefits. However, PA levels and adherence are often low. This...
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An elderly case of paraneoplastic anti-NMDA receptor encephalitis associated with large cell neuroendocrine carcinoma of the lung
BackgroundRecent studies have suggested that N-methyl-D-aspartate (NMDA) receptors are involved in the cell proliferation in several tumors. However,...
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Glucagon-like peptide-1 (GLP-1) receptor agonists for headache and pain disorders: a systematic review
BackgroundGlucagon-like peptide-1 (GLP-1) plays a crucial role in metabolic disorders by enhancing insulin secretion, inhibiting glucagon release,...
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Transcriptomic Expression of T2-Inflammation Genes in Peripheral Blood Mononuclear Cells and Longitudinal Clinical Outcomes in Asthma: Insights from the COREA Study
BackgroundGene expression can provide distinct information compared to clinical biomarkers in the context of longitudinal clinical outcomes in asthma...
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Novel physiologic predictors of positive airway pressure effectiveness (NICEPAP) study: rationale, design and methods
PurposeContinuous positive airway pressure (CPAP) is the primary therapy for obstructive sleep apnea (OSA); however the effectiveness of CPAP remains...
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Longitudinal lung function trajectories in response to azithromycin therapy for chronic lung disease in children with HIV infection: a secondary analysis of the BREATHE trial
BackgroundChronic lung disease (CLD) is common among children with HIV (CWH) including in those taking antiretroviral therapy (ART). Azithromycin has...
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Clinical Application of Different Doses of Hydromorphone Slow-Release Analgesia in Lumbar Fusion in Elderly Patients
IntroductionThe aim of this study is to examine the analgesic efficacy of varying doses of hydromorphone hydrochloride in conjunction with absorbable...
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Performing polysomnography in pre-school aged children: challenging parts of the procedure and risk factors for lead intolerance
PurposePediatric sleep apnea begins in toddlerhood when sleep is vital for neurocognitive development and rapid somatic growth. As polysomnography...
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Metagenomic next-generation sequencing promotes diagnosis and treatment of Pneumocystis jirovecii pneumonia in non-HIV infected children: a retrospective study
BackgroundMetagenomic next-generation sequencing (mNGS) excels in diagnosis of infection pathogens. We aimed to evaluate the performance of mNGS for...
