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The Broad Spectrum of Responses to Oxidative Stress in Proliferating Cells
Proliferating mammalian cells exhibit a broad spectrum of responses to oxidative stress, depending on the stress level encountered. Very low levels... -
Low Molecular Weight Antioxidants
Low molecular weight antioxidants are an important part of the antioxidative defense mechanisms of cells and organisms. This chapter gives a short... -
Environmental Oxidative Stress – Environmental Sources of ROS
Environmental factors are known sources for oxidative stress. In consequence of the numerous influences that define our environment, environmental... -
Endogenous Oxidant-Generating Systems
Although organisms respiring air oxygen use their energy sources in an optimal way they are threatened by the compulsory formation of reactive oxygen... -
Glutathione
Glutathione is the most abundant non-protein thiol in cells. It is a tripeptide with two important structural features: the thiol group and the... -
Modulation of Cellular Signaling Processes by Reactive Oxygen Species
Exposure of cells to reactive oxygen species (ROS) may result not only in cell death by excessive oxidation of biomolecules but also cause the... -
Chemical Modifications of Biomolecules by Oxidants
There is strong evidence in support of the oxidation of biomolecules during normal physiology and under conditions of environmental or pathological... -
DNA Repair: Mechanisms and Measurements
The early findings that significant amounts of modifications are induced to the cellular DNA both spontaneously and as a consequence of metabolism... -
Mitochondrial Free Radical Production, Antioxidant Defenses and Cell Signaling
Mitochondria were classically recognized as the organelles that produce the energy required to drive the endergonic processes of cell life, but now... -
Protein Repair and Degradation
Protein oxidation is one of the important processes taking place during oxidative stress. Numerous amino acids can be modified within proteins... -
Superoxide Dismutases and Catalase
Superoxide dismutases (SODs) and catalase represent the primary enzymatic defense against reactive oxygen species. Both enzymes are present in... -
Health Information Technology Use among Foreign-Born Adults of Middle Eastern and North African Descent in the United States
Health information technology (HIT) use among foreign-born adults of Middle Eastern and North African (MENA) descent is understudied. MENA Americans...
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Exploring the Religious Practice of Langar as a Route to Health Promotion in the Sikh Community in Northern England: A Qualitative Study
Cardiovascular disease and type 2 diabetes are prevalent among UK South Asians. Langar is a Sikh religious food practice that could be important in...
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Novel genomic variants related to visceral adiposity index (VAI) and body adiposity index (BAI) in Indian sib-pairs
BackgroundObesity is among the leading public health threats globally. Over the last few years, visceral adiposity index (VAI), and body adiposity...
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An unexpected case of an adnexal hydatid cyst in a pregnant woman: a case report
BackgroundCystic echinococcosis, also known as hydatid disease, is a chronic and endemic illness caused by infection with a parasite called Echinococc...
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Exploring fine-scale urban landscapes using satellite data to predict the distribution of Aedes mosquito breeding sites
BackgroundThe spread of mosquito-transmitted diseases such as dengue is a major public health issue worldwide. The Aedes aegypti mosquito, a primary...
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Work ability and return-to-work of patients with post-COVID-19: a systematic review and meta-analysis
BackgroundIn addition to several sequelae of post-COVID-19, individuals also experience significant limitations in work ability, resulting in...
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Atorvastatin exerts a preventive effect against steroid-induced necrosis of the femoral head by modulating Wnt5a release
Steroid-induced osteonecrosis of the femoral head (SONFH) is a prevalent form of osteonecrosis in young individuals. More efficacious clinical...
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Proactive home-based malaria management in rural communities of Bassar Health District in northern Togo from 2014 to 2017: PECADOM + , a pilot experiment
BackgroundTogo's National Malaria Control Programme has initiated an active home-based malaria management model for all age groups in rural areas of...
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Low Income, Ill-being, and Gender Inequality: Explaining Cross-National Variation in the Gendered Risk of Suffering Among the Poor
Scholars have long investigated the positive link between income and well-being, including its gender difference. However, little is known about (1)...