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Effects of Sex Steroids on Innate and Adaptive Immunity
Estrogens and androgens are classically recognized as reproductive sex steroid hormones because of their well-documented effects on reproductive... -
Diacerein mitigates endocrine and cardio-metabolic disruptions in experimental PCOS mice model by modulating AdipoR1/ PON 1
BackgroundThis study aimed to explore the impact of Diacerein (DIC) on endocrine and cardio-metabolic changes in polycystic ovarian syndrome (PCOS)...
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Assessment of the American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS™) with modification of the management recommendations for pediatric thyroid nodules
BackgroundThyroid nodules are unusual in children, but when present, they carry a higher risk for malignancy, as compared to adults. Several...
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Applying a User-Centered Design Framework to Develop a Remote Research Assessment Protocol for a Randomized Clinical Trial for Toddlers with Early Autism Characteristics
COVID-19 required many research teams to shift from in-person to remote assessments, which posed both procedural and theoretical challenges. While...
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Hospitalization- and death-related financial and employment effects in parents of children with life-limiting conditions: a fixed-effects analysis
The purpose of this study is to investigate out-of-pocket non-medical expenses and employment-related outcomes in families of children with...
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Obstetric cholestasis and its impact on the maternal outcome
AimTo evaluate the association of GDM and pre-eclampsia in women with obstetric cholestasis.
Materials and methodsPregnant women with > 28 weeks...
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PICC tip dislodgement causing massive pleural effusion and atelectasis with acute respiratory failure: a case report
Peripheral intravenous central catheter (PICC) is a common tool for intravenous infusion for children who need central venous access. Although it is...
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Magnetic Seizure Therapy in Management of Depression: A Narrative Review
Purpose of ReviewThis review aims to discuss historical aspects, mechanism of action, safety and efficacy, response predictors, and Magnetic Seizure...
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Refractory type 1 plastic bronchitis in a child; case report
BackgroundPlastic bronchitis (PB) is a rare pediatric pulmonary condition characterized by the production of branching bronchial casts that cause...
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Transient secondary pseudo-hypoaldosteronism in infants with urinary tract infections: systematic literature review
Infants with a congenital anomaly of the kidney and urinary tract sometimes present with hyponatremia, hyperkalemia, and metabolic acidosis due to...
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Trichohepatoenteric syndrome type 1: expanding the clinical spectrum of THES type 1 due to a homozygous variant in the SKIC3 gene
Trichohepatoenteric syndrome (THES), also known as phenotypic diarrhea or syndromic diarrhea, is a rare autosomal recessive genetic disorder caused...
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MicroRNA-21 modulates brown adipose tissue adipogenesis and thermogenesis in a mouse model of polycystic ovary syndrome
BackgroundPolycystic ovary syndrome (PCOS), the most common endocrine disorder in premenopausal women, is associated with increased obesity,...
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Caregiver-reported emotional-behavioral symptoms in Spanish youth during the COVID-19 pandemic: a longitudinal study
BackgroundCOVID-19 pandemic stressors affected youth’s mental health. This longitudinal study aims to explore these effects while considering...
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Longitudinal program evaluation of an inter-institutional mentorship network for pediatric rheumatology using a quality improvement framework
BackgroundThe American College of Rheumatology (ACR)/Childhood Arthritis and Rheumatology Research Alliance (CARRA) Mentoring Interest Group (AMIGO)...
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Determinants and willingness to practice obstetric analgesia among women attending antenatal clinic at Dr. Bogalech Gebre Memorial General Hospital Central Ethiopia: a cross-sectional study
BackgroundLabor pain is uniquely experienced and described by the woman giving birth, and it is often considered one of the most excruciating...
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The Impact of a Single, Brief Mindfulness Intervention on Cognitive and Emotional Reactivity: An EEG Study
ObjectivesMindfulness training produces behavioral and neuronal enhancements for executive and emotional control processes that strengthen with...
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The longitudinal growth trajectory of children with congenital hypothyroidism during the first 3 years of life
Congenital hypothyroidism (CH) is detected through a newborn screening program in Iran, enabling early detection and prompt treatment. This study...