Search
Search Results
-
The human Werner Syndrome as a model system for aging
The aging process is one of the most challenging biological pathways to understand. Applications of model systems for aging have contributed...
-
Aging and mitochondrial dysfunction in the filamentous fungus Podospora anserina
In the filamentous fungus Podospora anserina, mitochondria play a paramount role in life span control and aging. During aging, these organelles...
-
Aging and the programmed death phenomena
Biochemical mechanisms of the programmed death phenomena are considered at levels of unicellular organisms, mitochondria, cells, groups of cells, and...
-
Current Topics Regarding the Function of the Medial Temporal Lobe Memory System
The first clear insight that the medial temporal lobe of the human brain was in fact a system of anatomically connected structures that were...
-
Conditional senescence in prokaryotes
Bacteria are immortal in the sense that their capacity for reproduction appears limitless as long as the environment supports growth. However, this...
-
Do green plants age, and if so, how?
Time-dependent ageing-like processes in green plants are discussed and compared to gerontological changes in animals and other organisms. The...
-
Energy metabolism, anti-oxidant defense and aging in Caenorhabditis elegans
Food restriction and impaired gene function by mutation or RNAi treatment can extend the lifespan of Caenorhabditis elegans considerably. In contrast...
-
Yeast as a model for ageing and apoptosis research
Apoptosis is a form of programmed cell death with a crucial role in health and disease in metazoans. Recent findings demonstrate the existence of an...
-
Mammalian and bird aging, oxygen radicals, and restricted feeding
In this chapter, the relationship of aging with oxidative stress is reviewed. Endogenous tissue antioxidants do not determine aging because they...
-
Role of subcytotoxic stress in tissue ageing
Most commonly stress-induced premature senescence (SIPS) is defined as the long-term effects of subcytotoxic stress on proliferative cell types,...
-
Mitochondria, metabolism, and aging in yeast
Quantitative and qualitative changes in metabolism take place when the lifespan is extended in yeast either by genetic or nutritional manipulation....
-
SUMOylation of nuclear receptor Nor1/NR4A3 coordinates microtubule cytoskeletal dynamics and stability in neuronal cells
BackgroundNor1/NR4A3 is a member of the NR4A subfamily of nuclear receptors that play essential roles in regulating gene expression related to...
-
Where do Harris’ Checkerspots Lay their Eggs and what are the Consequences?
Where a female lays her eggs has strong implications for the survival of her offspring, an impetus that takes on particular significance for species...
-
Nerve Regeneration Through Differentiation of Endometrial-Derived Mesenchymal Stem Cells into Nerve-Like Cells Using Polyacrylonitrile/Chitosan Conduit and Berberine in a Rat Sciatic Nerve Injury Model
Nervous injuries are common in humans. One of the most advanced treatment methods is neural tissue engineering. This research aims to utilize...
-
The influence of sex-specific factors on biological transformations and health outcomes in aging processes
The aging process demonstrates notable differences between males and females, which are key factors in disease susceptibility and lifespan. The...
-
Progress and perspectives of metabolic biomarkers in human aortic dissection
BackgroundAortic dissection (AD) significantly threated human cardiovascular health, extensive clinical-scientific research programs have been...
-
Red-rumped agouti (Dasyprocta leporina linnaeus, 1758) yolk sac development during the early gestation stage
Phylogenetically, the yolk sac is an ancient structure in vertebrate evolution and crucial in the placentation of viviparous animals, playing an...
-
Intermittent Fasting Improves Social Interaction and Decreases Inflammatory Markers in Cortex and Hippocampus
Autism spectrum disorder (ASD) is a psychiatric condition characterized by reduced social interaction, anxiety, and stereotypic behaviors related to...
-
Impact and Interrelationships of Striatal Proteins, EPHB2, OPRM1, and PER2 on Mild Cognitive Impairment
With the global increase in life expectancy, there has been a rise in the incidence of cognitive impairments attributed to diverse etiologies....
-
Unleashing the Neurotherapeutic Potential: The Crucial Role of miR-206-3p in Facilitating Hsp90aa1-Mediated Central Nervous System Injuries During Heat Stroke
This study aims to explore the molecular mechanisms of miR-206-3p in regulating Hsp90aa1 and its involvement in the central nervous system (CNS)...
