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Current trends and future perspectives in hadron therapy: radiobiology
PurposeThe purpose of this article was to highlight current and future trends in radiobiology in an effort to move hadron therapy forward through the...
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Construction and application of medication reminder system: intelligent generation of universal medication schedule
BackgroundPatients with chronic conditions need multiple medications daily to manage their condition. However, most patients have poor compliance,...
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Ualign: pushing the limit of template-free retrosynthesis prediction with unsupervised SMILES alignment
MotivationRetrosynthesis planning poses a formidable challenge in the organic chemical industry, particularly in pharmaceuticals. Single-step...
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Exploration of COVID-19 data in Malaysia through mapper graph
Huge amounts of data have been collected from various sources during the COVID-19 pandemic, providing a unique opportunity for analysis, data-driven...
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Seamless site-directed mutagenesis in complex cloned DNA sequences using the RedEx method
Seamless site-directed mutagenesis is an important technique for studying protein functions, tuning enzyme catalytic activities and modifying genetic...
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DQMMBSC: design of an augmented deep Q-learning model for mining optimisation in IIoT via hybrid-bioinspired blockchain shards and contextual consensus
Single-chained blockchains are highly secure but cannot be scaled to larger IIoT (Internet of Industrial Things) network scenarios due to storage...
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Enhancing SNV identification in whole-genome sequencing data through the incorporation of known genetic variants into the minimap2 index
MotivationAlignment of reads to a reference genome sequence is one of the key steps in the analysis of human whole-genome sequencing data obtained...
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Enhancing OCT patch-based segmentation with improved GAN data augmentation and semi-supervised learning
For optimum performance, deep learning methods, such as those applied for retinal and choroidal layer segmentation in optical coherence tomography...
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Cancer mutationscape: revealing the link between modular restructuring and intervention efficacy among mutations
There is increasing evidence that biological systems are modular in both structure and function. Complex biological signaling networks such as gene...
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Evolution of hadron therapy from 1935 to 2005: a personal view
IntroductionHadron therapy is today an established modality in cancer radiation therapy that, world-wide, is available in about hundred centres....
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Benchmarking and integrating human B-cell receptor genomic and antibody proteomic profiling
Immunoglobulins (Ig), which exist either as B-cell receptors (BCR) on the surface of B cells or as antibodies when secreted, play a key role in the...
