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Antimalarial efficacy test of the aqueous crude leaf extract of Coriandrum sativum Linn.: an in vivo multiple model experimental study in mice infected with Plasmodium berghei
BackgroundMalaria continues to wreak havoc on the well-being of the community. Resistant parasites are jeopardizing the treatment. This is a wake-up...
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Unlocking the therapeutic potential of Nigella sativa extract: phytochemical analysis and revealing antimicrobial and antioxidant marvels
The growing global threat of antimicrobial resistance endangers both human and animal life, necessitating the urgent discovery of novel antimicrobial...
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Review of Malaysian medicinal plants with potential wound healing activity
Wound is defined as the damage to biological tissues including skin, mucous membranes and organ tissues. The acute wound heals in less than 4 weeks...
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Isolation and anti-neuroinflammation activity of sesquiterpenoids from Artemisia argyi: computational simulation and experimental verification
BackgroundArtemisia argyi is a traditional herbal medicine belonging to the genus Artemisia that plays an important role in suppressing...
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Effects of essential oil of Origanum onites and its major component carvacrol on the expression of toxicity pathway genes in HepG2 cells
BackgroundOriganum species have been used in various commercial constructions as a remedy against burns and wounds, agriculture, alcoholic drinks,...
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Meniscal Lesions in Multi-Ligament Knee Injuries
IntroductionMulti-ligament knee injuries (MLKIs) are rare and complex knee lesions and are potentially associated with intra-articular injuries,...
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A case series analysis: rehabilitation pathway for patients with postsurgical Stener lesions treated with a functional thermoplastic splint and early physiotherapy
Aims and objectivesThis study aims to evaluate the efficacy of postsurgical rehabilitation in patients with Stener lesions, focusing on the...
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Integrated network pharmacology and metabolomics to reveal the mechanism of Pinellia ternata inhibiting non-small cell lung cancer cells
Lung cancer is a malignant tumor with highly heterogeneous characteristics. A classic Chinese medicine, Pinellia ternata (PT), was shown to exert...
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Bioactivity and antibacterial effect of star anise biosynthesized silver nanoparticles against Streptococcus mutans: an in vitro study
BackgroundSilver nanoparticles (AgNPs) are receiving a lot of attention as a prospective antibacterial agent for use in caries prevention. The...
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Seagrass as a potential nutraceutical to decrease pro-inflammatory markers
BackgroundThe Pro-inflammatory mediators such as prostaglandin E2, nitric oxide and TNF-α are the key players in the stimulation of the inflammatory...
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Pasteurized form of a potential probiotic lactobacillus brevis IBRC-M10790 exerts anti-inflammatory effects on inflammatory bowel disease in vitro
BackgroundInflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder of the gastrointestinal system. So far, no treatment has...
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Two spurge species, Euphorbia resinifera O. Berg and Euphorbia officinarum subsp. echinus (Hook.f. & Coss.) Vindt inhibit colon cancer
BackgroundColon cancer, a prominent contributor to global cancer-related deaths, prompts the need for innovative treatment strategies. Euphorbia...
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Metabolic profiling and enzyme inhibitory activity of the essential oil of citrus aurantium fruit peel
BackgroundBitter orange ( Citrus aurantium ) is a fruiting shrub native to tropical and subtropical countries around the world and cultivated in many...
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Effects and mechanisms of puerarin against neuroblastoma: insights from bioinformatics and in vitro experiments
BackgroundNeuroblastoma, a prevalent solid tumor in children, often manifests with hidden onset sites, rapid growth, and high metastatic potential....
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Rosa × damascena Herrm. From Azaran region, Kashan: rich in saturated and unsaturated fatty acids with inhibitory effect against Proteus mirabilis
BackgroundOne of the most widely used medicinal plants in Iranian traditional medicine, Rosa × damascena Herrm. (mohammadi flower) that the people...
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Ilizarov External Fixator Versus Orthofix LRS in Management of Femoral Osteomyelitis: A Propensity Score Matched Analysis
PurposeTreatment of osteomyelitis (OM) is challenging. Ilizarov bone transport is a commonly used technique for management of OM. The recently...
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Developmental Dysplasia of the Hip and Laterality: The Importance of Graded Severity of the Contralateral Hip
BackgroundLaterality and bilaterality have been reported as prognostic variables in developmental dysplasia of the hip (DDH) outcomes. However, there...
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Four-Year Treatment Effect of Custom-Made Foot Orthosis on Pediatric Symptomatic Accessory Navicular Bone Combined with Flexible Flatfoot
PurposeCongenital accessory navicular bone (ANB) is a common variant in the foot and is prone to cause several clinical symptoms. Wearing custom-made...
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Comparing autologous blood, corticosteroid, and a combined injection of both for treating lateral epicondylitis: a randomized clinical trial
BackgroundBecause lateral epicondylitis is a common musculoskeletal disorder that affects the forearm's extensor tendons, an effective therapeutic...
