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  1. Effectiveness of synthetic versus autologous bone grafts in foot and ankle surgery: a systematic review and meta-analysis

    Background

    All orthopaedic procedures, comprising foot and ankle surgeries, seemed to show a positive trend, recently. Bone grafts are commonly...

    Amir Human Hoveidaei, Amirhossein Ghaseminejad-Raeini, ... Janet D. Conway in BMC Musculoskeletal Disorders
    Article Open access 13 July 2024
  2. Diffusion-tensor magnetic resonance imaging as a non-invasive assessment of extracellular matrix remodeling in lumbar paravertebral muscles of rats with sarcopenia

    Background

    Extracellular matrix (ECM) remodeling in skeletal muscle is a significant factor in the development of sarcopenia. This study aims to...

    **n-Chen Huang, Ji-Yao Ma, ... Bo He in BMC Musculoskeletal Disorders
    Article Open access 13 July 2024
  3. Retention of the posterior cruciate ligament stabilizes the medial femoral condyle during kneeling using a tibial insert with ball-in-socket medial conformity

    Purpose

    Resecting the posterior cruciate ligament (PCL) increases posterior laxity and increases the flexion gap more than the extension gap in the...

    Greg Harbison, Ed O’Donnell, ... M. L. Hull in International Orthopaedics
    Article 13 July 2024
  4. Soft tissue hemangioma of the right upper extremity with intraosseous extension and secondary intravascular papillary endothelial hyperplasia

    Intravascular papillary endothelial hyperplasia (IPEH), also known as Masson’s tumor, is an uncommon exuberant form of organizing thrombus that may...

    Rachel Bass, Gene Siegal, ... Yulia Melenevksy in Skeletal Radiology
    Article Open access 12 July 2024
  5. Changes in femoral anteversion after intramedullary nailing for pediatric femoral shaft fracture: a multicenter study

    Background

    The rotational change after using a flexible intramedullary (IM) nail for femoral shaft fractures has been a concern for many surgeons....

    Jae Jung Min, Soon-Sun Kwon, ... Moon Seok Park in BMC Musculoskeletal Disorders
    Article Open access 12 July 2024
  6. Medical imaging in cancer cachexia

    Cancer cachexia, often referred to as “wasting syndrome,” is characterized by fatigue, weakness, and involuntary weight loss. This syndrome is...

    Hyun Soo Ko, Ulrike Attenberger in Die Radiologie
    Article Open access 12 July 2024
  7. Multimodal training protocols on unstable rather than stable surfaces better improve dynamic balance ability in older adults

    Background

    There has been growing interest in using unstable devices in training protocols. This study aimed to assess the effectiveness of two...

    Alex Rizzato, Matteo Bozzato, ... Giuseppe Marcolin in European Review of Aging and Physical Activity
    Article Open access 12 July 2024
  8. Serum GM-CSF level is a predictor of treatment response to tocilizumab in rheumatoid arthritis patients: a prospective observational cohort study

    Background

    The aim of this prospective observational cohort study was to unveil the predictors of treatment response to tocilizumab (TCZ) therapy in...

    **gbo Su, Wenlu Hu, ... Lihua **ng in Arthritis Research & Therapy
    Article Open access 12 July 2024
  9. Preliminarily exploring the intraoperative ultrasonography characteristics of patients with degenerative cervical myelopathy

    Background

    How to quickly read and interpret intraoperative ultrasound (IOUS) images of patients with degenerative cervical myelopathy (DCM) to obtain...

    Wenfen Liu, Jiachun Li, ... Zuofeng Xu in BMC Musculoskeletal Disorders
    Article Open access 12 July 2024
  10. Exosomes derived from human urine–derived stem cells ameliorate IL-1β-induced intervertebral disk degeneration

    Background

    Human intervertebral disk degeneration (IVDD) is a sophisticated degenerative pathological process. A key cause of IVDD progression is...

    Guang Qian, Yueming Yu, ... Minghai Wang in BMC Musculoskeletal Disorders
    Article Open access 12 July 2024
  11. Cardiac rehabilitation in children and adolescents with long QT syndrome: the RYTHMO’FIT pilot study

    Background

    To assess the feasibility, acceptability, safety, and short-term benefits of a tailored cardiac rehabilitation program for children and...

    Luc Souilla, Sophie Guillaumont, ... Pascal Amedro in BMC Sports Science, Medicine and Rehabilitation
    Article Open access 12 July 2024
  12. The dual amylin and calcitonin receptor agonist KBP-336 elicits a unique combination of weight loss, antinociception and bone protection – a novel disease-modifying osteoarthritis drug

    Background

    Despite the extensive research to provide a disease-modifying osteoarthritis drug (DMOAD), there is still no approved DMOAD. Dual amylin...

    Khaled Elhady Mohamed, Anna Thorsø Larsen, ... Kim Henriksen in Arthritis Research & Therapy
    Article Open access 12 July 2024
  13. The effect of large channel-based foraminoplasty on lumbar biomechanics in percutaneous endoscopic discectomy: a finite element analysis

    Background

    This study aimed to evaluate the effect of foraminoplasty using large-channel endoscopy during TESSYS on the biomechanics of the lumbar...

    Wei Sun, Duohua Li, ... Dongying Wu in Journal of Orthopaedic Surgery and Research
    Article Open access 12 July 2024
  14. Blood pressure is associated with knee pain severity in middle-aged and elderly individuals with or at risks for osteoarthritis: data from the Osteoarthritis Initiative

    Background

    Hypertension is a common comorbidity of osteoarthritis (OA). Joint pain is the main clinical manifestation of OA. Knowledge about the...

    Yao Liu, Guiying Du in BMC Musculoskeletal Disorders
    Article Open access 12 July 2024
  15. Myocardial work by pressure-strain loop is associated with molecular imaging of fibroblast activation in hypertensive hearts using 99mTc-HFAPI SPECT

    99m Tc-HFAPI can visualize fibroblast activation in hypertensive hearts. Myocardial work (MW) reflects the cardiac mechanical properties after...

    Chenlei Leng, Cuncun Hua, ... Qizhe Cai in The International Journal of Cardiovascular Imaging
    Article 12 July 2024
  16. The relationship between the duration and the retraction and atrophy grades in traumatic isolated full-thickness supraspinatus tears in young patients

    Background

    The study aimed to determine the grade of retraction and atrophy according to the time elapsed in traumatic isolated full-thickness...

    Gokhan Ilyas, Fikri Burak Ipci, ... Ercument Egeli in BMC Musculoskeletal Disorders
    Article Open access 12 July 2024
  17. Enhanced γ-H2AX Foci Frequency and Altered Gene Expression in Participants Exposed to Ionizing Radiation During I-131 Nuclear Medicine Procedures

    Purpose

    Ionizing radiation-based technologies are extensively used in the diagnosis and treatment of diseases. While utilizing the technologies,...

    Shruti Hariharan, Smruthi Seethashankar, ... Venkatachalam Perumal in Nuclear Medicine and Molecular Imaging
    Article 12 July 2024
  18. Efficacy comparison between intramedullary nail fixation and plate fixation in distal tibia fractures: a meta-analysis of randomized controlled trials

    Background

    Intramedullary nail (IMN) and plate fixation are the most commonly used surgical modalities for distal tibia fractures. However, the...

    Article Open access 12 July 2024
  19. The pivotal role of endoplasmic reticulum in FDG uptake in cancer cells

    Francesca Vitale, Maddalena Ghelardoni, ... Gianmario Sambuceti in EJNMMI Research
    Article Open access 12 July 2024
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