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Knockout Transporter Cell Lines to Assess Substrate Potential Towards Efflux Transporters
P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and multidrug resistance transporter 2 (MRP2) are efflux transporters involved in the...
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Investigating worldwide strong motion databases to derive a collection of free-field records to select design-compatible waveforms for Switzerland
The process of choosing ground motions typically relies on assembling a collection of ground motions that match a desired spectrum. This selection...
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Non-destructive Ripeness Detection of Avocados (Persea Americana Mill) using Vision and Tactile Perception Information Fusion Method
Vision (skin color) and tactile (firmness) characteristics of avocado are important characteristics associated with the level of ripeness. Avocados...
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Examining temporal changes in model-optimized parameters using longitudinal hemodynamic measurements
BackgroundWe previously applied hemodynamic data to personalize a mathematical model of the circulation expressed as physically interpretable...
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Effects of exposure to trihalomethanes in swimming pool waters on metabolomics profile: a randomized parallel design trial
Biological mechanisms of exposure to Trihalomethanes (THMs) in swimming pools remain unclear. Investigation of short-term changes in metabolomic...
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Yoda1 pretreated BMSC derived exosomes accelerate osteogenesis by activating phospho-ErK signaling via Yoda1-mediated signal transmission
Segmental bone defects, arising from factors such as trauma, tumor resection, and congenital malformations, present significant clinical challenges...
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Automatic localization of cochlear implant electrodes using cone beam computed tomography images
BackgroundCochlear implants (CI) are implantable medical devices that enable the perception of sounds and the understanding of speech by electrically...
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Metagenomic Next-Generation Sequencing as an Effective Diagnostic Tool for Talaromycosis in HIV-Negative Patients
The diagnosis of Talaromyces marneffei infection in HIV-negative patients remains challenging. There is an urgent need for rapid and convenient...
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Mechanistic insights into the conversion of flavin adenine dinucleotide (FAD) to 8-formyl FAD in formate oxidase: a combined experimental and in-silico study
Formate oxidase (FOx), which contains 8-formyl flavin adenine dinucleotide (FAD), exhibits a distinct advantage in utilizing ambient oxygen molecules...
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A Comprehensive on Synthesis and Antimicrobial Evaluation of Substituted-Arylideneamino-5-(5-Chlorobenzofuran-2-yl)-1, 2, 4-Triazole-3-Thiol Derivatives/ Schiff Bases
Schiff bases are well known and popular classes of organic compounds containing imine (R 2 C = NH) group that are widely used as catalysts and...
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An end-to-end approach for single-cell infrared absorption spectroscopy of bacterial inclusion bodies: from AFM-IR measurement to data interpretation of large sample sets
BackgroundInclusion bodies (IBs) are well-known subcellular structures in bacteria where protein aggregates are collected. Various methods have...
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Environmental Design Considerationsfor Somatic Embryogenesis
In addition to the biomolecular, physiological, and biochemical aspects of somatic embryogenesis, careful design of environmental conditions is...
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Origin, Development and Structure of Somatic Embryosin Selected Bulbous Ornamentals: BAP as Inducer
Somatic embryogenesis in three important ornamentals is discussed in this chapter. Direct somatic embryo development on the explant tissues...
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Differential Gene Expression During Somatic Embryogenesis
Somatic embryogenesis is a complex developmental program in which somatic cells are induced for a commitment towards forming totipotent...
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Embryogenesis in Catharanthus roseus: Roles of Some External Factors in Proliferation, Maturation and Germination of Embryos
Catharanthus roseus is an important medicinal plant that contains two well-known anticancerous alkaloids, vincristine and vinblastine. Cell...
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Participation of Plant Hormones in Determination and Progression of Somatic Embryogenesis
In vitro culture protocols have been developed for many species, mainly using empirical approaches, to induce somatic embryogenesis from various...
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Why Somatic Plant Cells Start to form Embryos?
Embryogenesis in plants is not restricted to the fertilized egg cell but can be naturally or artificially induced in many different cell types,...
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Somatic and Zygotic Embryogenesis in Avocado
Avocado is a species widely cultivated for its highly nutritious fruit. Currently, soil-borne diseases such as Phytophthora root rot are severe...