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  1. The resistance switching performance of the memristor improved effectively by inserting carbon quantum dots (CQDs) for digital information processing

    As an emerging information device that adapts to development of the big data era, memristor has attracted much attention due to its advantage in...

    Tianqi Yu, Jie Li, ... Zhiwei Zhao in Nano Research
    Article 13 July 2024

  2. Environmental Oxidative Stress – Environmental Sources of ROS

    Environmental factors are known sources for oxidative stress. In consequence of the numerous influences that define our environment, environmental...
    Peter Schröder, Jean Krutmann in Reactions, Processes
    Chapter

  3. Endogenous Oxidant-Generating Systems

    Although organisms respiring air oxygen use their energy sources in an optimal way they are threatened by the compulsory formation of reactive oxygen...
    Hans Nohl, Andrey V. Kozlov, ... Katrin Staniek in Reactions, Processes
    Chapter

  4. Low Molecular Weight Antioxidants

    Low molecular weight antioxidants are an important part of the antioxidative defense mechanisms of cells and organisms. This chapter gives a short...
    Tilman Grune, Peter Schröder, Hans K. Biesalski in Reactions, Processes
    Chapter

  5. Modulation of Cellular Signaling Processes by Reactive Oxygen Species

    Exposure of cells to reactive oxygen species (ROS) may result not only in cell death by excessive oxidation of biomolecules but also cause the...
    Lars-Oliver Klotz in Reactions, Processes
    Chapter

  6. Glutathione

    Glutathione is the most abundant non-protein thiol in cells. It is a tripeptide with two important structural features: the thiol group and the...
    Juan Sastre, Federico V. Pallardo, Jose Viña in Reactions, Processes
    Chapter

  7. The Broad Spectrum of Responses to Oxidative Stress in Proliferating Cells

    Proliferating mammalian cells exhibit a broad spectrum of responses to oxidative stress, depending on the stress level encountered. Very low levels...
    Kelvin J. A. Davies in Reactions, Processes
    Chapter

  8. Chemical Modifications of Biomolecules by Oxidants

    There is strong evidence in support of the oxidation of biomolecules during normal physiology and under conditions of environmental or pathological...
    Helen R. Griffiths in Reactions, Processes
    Chapter

  9. CCT6A promotes cell proliferation in colon cancer by targeting BIRC5 associated with p53 status

    Chaperonin-containing TCP1 (CCT) is a multi-subunit complex, known to participate the correct folding of many proteins. Currently, the mechanism...

    Han Zhang, Taotao Zheng, ... Huawen Liu in Cancer Gene Therapy
    Article 13 July 2024

  10. Superoxide Dismutases and Catalase

    Superoxide dismutases (SODs) and catalase represent the primary enzymatic defense against reactive oxygen species. Both enzymes are present in...
    Grzegorz Bartosz in Reactions, Processes
    Chapter

  11. Protein Repair and Degradation

    Protein oxidation is one of the important processes taking place during oxidative stress. Numerous amino acids can be modified within proteins...
    Diana Poppek, Tilman Grune in Reactions, Processes
    Chapter

  12. DNA Repair: Mechanisms and Measurements

    The early findings that significant amounts of modifications are induced to the cellular DNA both spontaneously and as a consequence of metabolism...
    Bente Riis, Henrik E. Poulsen in Reactions, Processes
    Chapter

  13. Mitochondrial Free Radical Production, Antioxidant Defenses and Cell Signaling

    Mitochondria were classically recognized as the organelles that produce the energy required to drive the endergonic processes of cell life, but now...
    Enrique Cadenas, Alberto Boveris in Reactions, Processes
    Chapter

  14. Gut Microbiota in Primary Osteoporosis: a Systematic Review

    The link between gut microbiota (GM) and primary osteoporosis has garnered substantial attention. In this study, we conducted a systematic review...

    Jiangxun Ji, Feihong Cai, ... Yongjun Wang in Phenomics
    Article Open access 12 July 2024

  15. Effect of dipeptidyl peptidase-4 inhibitors on tumor necrosis factor alpha levels in patients with type 2 diabetes mellitus

    Aims

    Dipeptidyl peptidase-4 inhibitors (DPP-4i) served as oral antidiabetic agents for treatment of type 2 diabetes mellitus (T2DM). Although an...

    Lijia Zhao, Jie Meng, ... **n Liu in European Journal of Medical Research
    Article Open access 12 July 2024

  16. The clinical value of artificial intelligence in assisting junior radiologists in thyroid ultrasound: a multicenter prospective study from real clinical practice

    Background

    This study is to propose a clinically applicable 2-echelon (2e) diagnostic criteria for the analysis of thyroid nodules such that low-risk...

    Dong Xu, Lin Sui, ... Li** Wang in BMC Medicine
    Article Open access 12 July 2024

  19. Development and preliminary evaluation of a suicidal risk assessment protocol in a randomised controlled trial using the Patient Health Questionnaire (PHQ-9)

    Background

    Participants in research trials often disclose severe depression symptoms, including thoughts of self-harm and suicidal ideation, in...

    Vari Wileman, Serena McGuinness, ... Rona Moss-Morris in Trials
    Article Open access 12 July 2024

  20. Specific CD4+ T cell phenotypes associate with bacterial control in people who ‘resist’ infection with Mycobacterium tuberculosis

    A subset of individuals exposed to Mycobacterium tuberculosis ( Mtb ) that we refer to as ‘resisters’ (RSTR) show evidence of IFN-γ − T cell responses...

    Meng Sun, Jolie M. Phan, ... Chetan Seshadri in Nature Immunology
    Article Open access 12 July 2024
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