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English Biomedicine, general Immunology Pharmacology/toxicology

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  1. Toxicological effect of acetaminophen, metamizole, and nimesulide cocktail on early development of zebrafish

    Background

    Several countries’ most incorrectly discarded medicines are acetaminophen (ACM), metamizole (MTZ), and nimesulide (NMS). These xenobiotics...

    Wellington Fernandes de Carvalho, Ednalva de Souza Pereira Lima, ... Hélio Batista Santos in DARU Journal of Pharmaceutical Sciences
    Article 11 July 2024

  2. Understand the Stabilization Engineering of Ascorbic Acid, Map** the Scheme for Stabilization, and Advancement.

    Abstract

    Vitamin C is extensively used in cosmetic formulation, howbeit stability is the supreme demerit that limits its use in beautifying products....

    Om Shelke, Krishna Phani Chandra Susarla, Manish Bankar in AAPS PharmSciTech
    Article 11 July 2024

  5. From bench to bedside: the application of cannabidiol in glioma

    Glioma is the most common malignant tumor in central nervous system, with significant health burdens to patients. Due to the intrinsic...

    Shiying Feng, Yuanming Pan, ... Zhiqiang Hao in Journal of Translational Medicine
    Article Open access 11 July 2024

  6. N6-methyladenosine modification of circMARK2 enhances cytoplasmic export and stabilizes LIN28B, contributing to the progression of Wilms tumor

    Background

    The potential involvement of circular RNAs (circRNAs) and N 6 -methyladenosine (m 6 A) modification in the progression of Wilms tumor (WT) has...

    Guannan Shu, Zhang Zhao, ... Guochang Liu in Journal of Experimental & Clinical Cancer Research
    Article Open access 11 July 2024

  7. Snn and sound: a comprehensive review of spiking neural networks in sound

    The rapid advancement of AI and machine learning has significantly enhanced sound and acoustic recognition technologies, moving beyond traditional...

    Suwhan Baek, Jaewon Lee in Biomedical Engineering Letters
    Article 11 July 2024

  8. Adopting STOPP/START Criteria Version 3 in Clinical Practice: A Q&A Guide for Healthcare Professionals

    The growing complexity of geriatric pharmacotherapy necessitates effective tools for mitigating the risks associated with polypharmacy. The Screening...

    Carlotta Lunghi, Marco Domenicali, ... Elisabetta Poluzzi in Drug Safety
    Article Open access 11 July 2024

  9. Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care

    Background and objectives

    Clinical data are essential for develo** cloud platforms for intelligent diagnosis and treatment decision of diseases....

    **nyu Zhao, Zhenquan Wu, ... Guoming Zhang in EPMA Journal
    Article 11 July 2024

  10. Digital biomarkers for non-motor symptoms in Parkinson’s disease: the state of the art

    Digital biomarkers that remotely monitor symptoms have the potential to revolutionize outcome assessments in future disease-modifying trials in...

    Jules M. Janssen Daalen, Robin van den Bergh, ... Bastiaan R. Bloem in npj Digital Medicine
    Article Open access 11 July 2024

  11. Environmental Oxidative Stress – Environmental Sources of ROS

    Environmental factors are known sources for oxidative stress. In consequence of the numerous influences that define our environment, environmental...
    Peter Schröder, Jean Krutmann in Reactions, Processes
    Chapter

  12. Endogenous Oxidant-Generating Systems

    Although organisms respiring air oxygen use their energy sources in an optimal way they are threatened by the compulsory formation of reactive oxygen...
    Hans Nohl, Andrey V. Kozlov, ... Katrin Staniek in Reactions, Processes
    Chapter

  13. Low Molecular Weight Antioxidants

    Low molecular weight antioxidants are an important part of the antioxidative defense mechanisms of cells and organisms. This chapter gives a short...
    Tilman Grune, Peter Schröder, Hans K. Biesalski in Reactions, Processes
    Chapter

  14. Modulation of Cellular Signaling Processes by Reactive Oxygen Species

    Exposure of cells to reactive oxygen species (ROS) may result not only in cell death by excessive oxidation of biomolecules but also cause the...
    Lars-Oliver Klotz in Reactions, Processes
    Chapter

  15. Glutathione

    Glutathione is the most abundant non-protein thiol in cells. It is a tripeptide with two important structural features: the thiol group and the...
    Juan Sastre, Federico V. Pallardo, Jose Viña in Reactions, Processes
    Chapter

  16. The Broad Spectrum of Responses to Oxidative Stress in Proliferating Cells

    Proliferating mammalian cells exhibit a broad spectrum of responses to oxidative stress, depending on the stress level encountered. Very low levels...
    Kelvin J. A. Davies in Reactions, Processes
    Chapter

  17. Tomatidine, a Steroidal Alkaloid, Synergizes with Cisplatin to Inhibit Cell Viability and Induce Cell Death Selectively on FLT3-ITD+ Acute Myeloid Leukemia Cells

    Background

    Acute Myeloid Leukemia (AML) is a hematological cancer that frequently presents with a range of side effects and drug resistance during...

    Havva Berre Ayvaz, Münevver Yenigül, Emel Başak Gencer Akçok in Cell Biochemistry and Biophysics
    Article 11 July 2024

  18. The Impact of the VEGF/VEGFR2/PI3K/AKT Signaling Axis on the Proliferation and Migration Abilities of Human Dental Pulp Stem Cells

    The potential therapeutic benefits of human dental pulp stem cells (HDPSCs) in dental regenerative medicine have been demonstrated. However, little...

    Gang Pan, Qianwen Zhou, ... Yingxue Zhang in Cell Biochemistry and Biophysics
    Article 11 July 2024

  19. A phase III randomized clinical trial comparing laparoscopic radical hysterectomy based on open state with abdominal radical hysterectomy in patients with early-stage cervical cancer

    Background

    Cervical cancer is the fourth most frequently diagnosed cancer and the fourth leading cause of cancer death in women, The standard...

    **n Zhao, Yansong Liu, ... Yulin Shi in Trials
    Article Open access 11 July 2024

  20. Neuroprotective Effects of Dehydroepiandrosterone and Hericium erinaceus in Scopolamine-induced Alzheimer’s Diseases-like Symptoms in Male Rats

    Background

    The neuroprotective effects of Dehydroepiandrosterone (DHEA) and Hericium erinaceus (H . erinaceus ) mushroom extract against...

    Majid Shirvani, Fatemeh Nouri, ... Mojdeh Mohammadi in Cell Biochemistry and Biophysics
    Article 11 July 2024
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