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  1. The clinical value of artificial intelligence in assisting junior radiologists in thyroid ultrasound: a multicenter prospective study from real clinical practice

    Background

    This study is to propose a clinically applicable 2-echelon (2e) diagnostic criteria for the analysis of thyroid nodules such that low-risk...

    Dong Xu, Lin Sui, ... Li** Wang in BMC Medicine
    Article Open access 12 July 2024
  2. Effect of dipeptidyl peptidase-4 inhibitors on tumor necrosis factor alpha levels in patients with type 2 diabetes mellitus

    Aims

    Dipeptidyl peptidase-4 inhibitors (DPP-4i) served as oral antidiabetic agents for treatment of type 2 diabetes mellitus (T2DM). Although an...

    Lijia Zhao, Jie Meng, ... **n Liu in European Journal of Medical Research
    Article Open access 12 July 2024
  3. Contribution of plasma levels of VEGF-A and angiopoietin-2 in addition to a genetic variant in KCNAB1 to predict the risk of bevacizumab-induced hypertension

    Bevacizumab-induced hypertension poses a therapeutic challenge and identifying biomarkers for hypertension can enhance therapy safety. Lower plasma...

    Julia C. F. Quintanilha, William Kevin Kelly, Federico Innocenti in The Pharmacogenomics Journal
    Article 12 July 2024
  4. Comment on “Chemical vapor deposition synthesis and Raman scattering investigation of quasi-one-dimensional ZrS3 nanoflakes”

    A fundamentally crucial suggestion to rectify the fits to the high-resolution X-ray photoemission spectroscopy (XPS) raw data for the S 2p core level...

    Archit Dhingra in Nano Research
    Article 12 July 2024
  5. Exploring the inverse relationship between serum total bilirubin and systemic immune-inflammation index: insights from NHANES data (2009–2018)

    Background

    Bilirubin is known for its multifaceted attributes, including antioxidant, anti-inflammatory, immunomodulatory, and antiapoptotic...

    Shan-Shan Huang, Yi Ding, ... Zhou-**n Yang in European Journal of Medical Research
    Article Open access 12 July 2024
  6. A genetic variant in the TAPBP gene enhances cervical cancer susceptibility by increasing m6A modification

    Genetic variants can affect gene expression by altering the level of N6-methyladenosine (m 6 A) modifications. A better understanding of the...

    **g Hu, Shizhi Wang, ... Hua ** in Archives of Toxicology
    Article 12 July 2024
  7. Presence of Fusobacterium nucleatum in relation to patient survival and an acidic environment in oesophagogastric junction and gastric cancers

    Background

    Fusobacterium nucleatum inhabits the oral cavity and affects the progression of gastrointestinal cancer. Our prior findings link F....

    Yoshihiro Hara, Yoshifumi Baba, ... Hideo Baba in British Journal of Cancer
    Article 12 July 2024
  8. Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study

    Background

    Most gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has...

    Hui-Jen Tsai, Yan-Shen Shan, ... Tsang-En Wang in BMC Cancer
    Article Open access 11 July 2024
  9. Biomechanical evaluation of different medial column fixation patterns for valgus pilon fractures

    Background

    The purpose of this study was to perform a biomechanical analysis to compare different medial column fixation patterns for valgus pilon...

    Bing-Hao Wang, Bin-Bin Zhang, ... Yi Zhu in BMC Musculoskeletal Disorders
    Article Open access 11 July 2024
  10. Machine learning to optimize literature screening in medical guideline development

    Objectives

    In a time of exponential growth of new evidence supporting clinical decision-making, combined with a labor-intensive process of selecting...

    Wouter Harmsen, Janke de Groot, ... Rens van de Schoot in Systematic Reviews
    Article Open access 11 July 2024
  11. Assessing knowledge of hypertension and diabetes mellitus among informal healthcare providers in urban slums in southeastern Nigeria

    Informal healthcare providers (IHPs) often serve as the first point of contact for healthcare services for non-communicable diseases in urban slums...

    Chinyere Ojiugo Mbachu, Ifeyinwa Arize, ... Obinna Onwujekwe in Discover Public Health
    Article Open access 11 July 2024
  12. Digital biomarkers for non-motor symptoms in Parkinson’s disease: the state of the art

    Digital biomarkers that remotely monitor symptoms have the potential to revolutionize outcome assessments in future disease-modifying trials in...

    Jules M. Janssen Daalen, Robin van den Bergh, ... Bastiaan R. Bloem in npj Digital Medicine
    Article Open access 11 July 2024
  13. Survey on pattern of myopia in school children in Hangzhou after the COVID-19 pandemic: a school-based vision screening study

    Background

    Myopia is a major health issue around the world. Myopia in children has increased significantly during the COVID-19 pandemic in China, but...

    Ting He, Lei Yin, ... Ting Shen in BMC Public Health
    Article Open access 11 July 2024
  14. Fasting in combination with the cocktail Sorafenib:Metformin blunts cellular plasticity and promotes liver cancer cell death via poly-metabolic exhaustion

    Purpose

    Dual-Interventions targeting glucose and oxidative metabolism are receiving increasing attention in cancer therapy. Sorafenib (S) and...

    Juan L. López-Cánovas, Beatriz Naranjo-Martínez, Alberto Diaz-Ruiz in Cellular Oncology
    Article Open access 11 July 2024
  15. Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care

    Background and objectives

    Clinical data are essential for develo** cloud platforms for intelligent diagnosis and treatment decision of diseases....

    **nyu Zhao, Zhenquan Wu, ... Guoming Zhang in EPMA Journal
    Article 11 July 2024
  16. The association between air pollution and obesity: an umbrella review of meta-analyses and systematic reviews

    The objective of this umbrella review was to investigate comprehensive and synthesized evidence of the association between ambient air pollution and...

    Chengwen Luo, Ting Wei, ... Tao-Hsin Tung in BMC Public Health
    Article Open access 11 July 2024
  17. The relationship between follicle-stimulating hormone and metabolic dysfunction-associated fatty liver disease in men

    Objectives

    The present study aimed to investigate the relationship between male hormones and metabolic dysfunction-associated fatty liver disease...

    Dong-Hua Bin, Fang Liu, ... Gui-**ang Tian in Nutrition & Diabetes
    Article Open access 11 July 2024
  18. Construction and validation of a nomogram for blood transfusion after open reduction and internal fixation (ORIF) of proximal humeral fractures in the elderly: a cross-sectional study

    Purpose

    Few studies have focused on the risk factors leading to postoperative blood transfusion after open reduction and internal fixation (ORIF) of...

    Lu-ying Chen, Ji-qi Wang, ... Yong-zeng Feng in BMC Musculoskeletal Disorders
    Article Open access 11 July 2024
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