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The clinical value of artificial intelligence in assisting junior radiologists in thyroid ultrasound: a multicenter prospective study from real clinical practice
BackgroundThis study is to propose a clinically applicable 2-echelon (2e) diagnostic criteria for the analysis of thyroid nodules such that low-risk...
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Effect of dipeptidyl peptidase-4 inhibitors on tumor necrosis factor alpha levels in patients with type 2 diabetes mellitus
AimsDipeptidyl peptidase-4 inhibitors (DPP-4i) served as oral antidiabetic agents for treatment of type 2 diabetes mellitus (T2DM). Although an...
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Contribution of plasma levels of VEGF-A and angiopoietin-2 in addition to a genetic variant in KCNAB1 to predict the risk of bevacizumab-induced hypertension
Bevacizumab-induced hypertension poses a therapeutic challenge and identifying biomarkers for hypertension can enhance therapy safety. Lower plasma...
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Comment on “Chemical vapor deposition synthesis and Raman scattering investigation of quasi-one-dimensional ZrS3 nanoflakes”
A fundamentally crucial suggestion to rectify the fits to the high-resolution X-ray photoemission spectroscopy (XPS) raw data for the S 2p core level...
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Exploring the inverse relationship between serum total bilirubin and systemic immune-inflammation index: insights from NHANES data (2009–2018)
BackgroundBilirubin is known for its multifaceted attributes, including antioxidant, anti-inflammatory, immunomodulatory, and antiapoptotic...
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A genetic variant in the TAPBP gene enhances cervical cancer susceptibility by increasing m6A modification
Genetic variants can affect gene expression by altering the level of N6-methyladenosine (m 6 A) modifications. A better understanding of the...
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Presence of Fusobacterium nucleatum in relation to patient survival and an acidic environment in oesophagogastric junction and gastric cancers
BackgroundFusobacterium nucleatum inhabits the oral cavity and affects the progression of gastrointestinal cancer. Our prior findings link F....
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Survival of advanced/recurrent gastrointestinal stromal tumors treated with tyrosine kinase inhibitors in Taiwan: a nationwide registry study
BackgroundMost gastrointestinal stromal tumors (GISTs) harbor c-KIT or PDGFRA mutations. Administration of tyrosine kinase inhibitors (TKIs) has...
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Biomechanical evaluation of different medial column fixation patterns for valgus pilon fractures
BackgroundThe purpose of this study was to perform a biomechanical analysis to compare different medial column fixation patterns for valgus pilon...
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Machine learning to optimize literature screening in medical guideline development
ObjectivesIn a time of exponential growth of new evidence supporting clinical decision-making, combined with a labor-intensive process of selecting...
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Assessing knowledge of hypertension and diabetes mellitus among informal healthcare providers in urban slums in southeastern Nigeria
Informal healthcare providers (IHPs) often serve as the first point of contact for healthcare services for non-communicable diseases in urban slums...
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Digital biomarkers for non-motor symptoms in Parkinson’s disease: the state of the art
Digital biomarkers that remotely monitor symptoms have the potential to revolutionize outcome assessments in future disease-modifying trials in...
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Survey on pattern of myopia in school children in Hangzhou after the COVID-19 pandemic: a school-based vision screening study
BackgroundMyopia is a major health issue around the world. Myopia in children has increased significantly during the COVID-19 pandemic in China, but...
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Fasting in combination with the cocktail Sorafenib:Metformin blunts cellular plasticity and promotes liver cancer cell death via poly-metabolic exhaustion
PurposeDual-Interventions targeting glucose and oxidative metabolism are receiving increasing attention in cancer therapy. Sorafenib (S) and...
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Eyecare-cloud: an innovative electronic medical record cloud platform for pediatric research and clinical care
Background and objectivesClinical data are essential for develo** cloud platforms for intelligent diagnosis and treatment decision of diseases....
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The association between air pollution and obesity: an umbrella review of meta-analyses and systematic reviews
The objective of this umbrella review was to investigate comprehensive and synthesized evidence of the association between ambient air pollution and...
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The relationship between follicle-stimulating hormone and metabolic dysfunction-associated fatty liver disease in men
ObjectivesThe present study aimed to investigate the relationship between male hormones and metabolic dysfunction-associated fatty liver disease...
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Construction and validation of a nomogram for blood transfusion after open reduction and internal fixation (ORIF) of proximal humeral fractures in the elderly: a cross-sectional study
PurposeFew studies have focused on the risk factors leading to postoperative blood transfusion after open reduction and internal fixation (ORIF) of...