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Antimalarial efficacy test of the aqueous crude leaf extract of Coriandrum sativum Linn.: an in vivo multiple model experimental study in mice infected with Plasmodium berghei
BackgroundMalaria continues to wreak havoc on the well-being of the community. Resistant parasites are jeopardizing the treatment. This is a wake-up...
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Knowledge in motion: temporal dynamics of wild food plant use in the Polish-Lithuanian-Belarusian border region
BackgroundUnderstanding how Local Ecological Knowledge (LEK) evolves over time is crucial for fostering social and environmental responsibility. This...
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Unlocking the therapeutic potential of Nigella sativa extract: phytochemical analysis and revealing antimicrobial and antioxidant marvels
The growing global threat of antimicrobial resistance endangers both human and animal life, necessitating the urgent discovery of novel antimicrobial...
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Pharmacological activity and clinical application analysis of traditional Chinese medicine ginger from the perspective of one source and multiple substances
All types of ginger have common fundamental components, although they possess distinct strengths and inclinations when it comes to effectiveness and...
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Review of Malaysian medicinal plants with potential wound healing activity
Wound is defined as the damage to biological tissues including skin, mucous membranes and organ tissues. The acute wound heals in less than 4 weeks...
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Effects of essential oil of Origanum onites and its major component carvacrol on the expression of toxicity pathway genes in HepG2 cells
BackgroundOriganum species have been used in various commercial constructions as a remedy against burns and wounds, agriculture, alcoholic drinks,...
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Isolation and anti-neuroinflammation activity of sesquiterpenoids from Artemisia argyi: computational simulation and experimental verification
BackgroundArtemisia argyi is a traditional herbal medicine belonging to the genus Artemisia that plays an important role in suppressing...
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Integrated network pharmacology and metabolomics to reveal the mechanism of Pinellia ternata inhibiting non-small cell lung cancer cells
Lung cancer is a malignant tumor with highly heterogeneous characteristics. A classic Chinese medicine, Pinellia ternata (PT), was shown to exert...
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Bioactivity and antibacterial effect of star anise biosynthesized silver nanoparticles against Streptococcus mutans: an in vitro study
BackgroundSilver nanoparticles (AgNPs) are receiving a lot of attention as a prospective antibacterial agent for use in caries prevention. The...
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Seagrass as a potential nutraceutical to decrease pro-inflammatory markers
BackgroundThe Pro-inflammatory mediators such as prostaglandin E2, nitric oxide and TNF-α are the key players in the stimulation of the inflammatory...
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Two spurge species, Euphorbia resinifera O. Berg and Euphorbia officinarum subsp. echinus (Hook.f. & Coss.) Vindt inhibit colon cancer
BackgroundColon cancer, a prominent contributor to global cancer-related deaths, prompts the need for innovative treatment strategies. Euphorbia...
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Metabolic profiling and enzyme inhibitory activity of the essential oil of citrus aurantium fruit peel
BackgroundBitter orange ( Citrus aurantium ) is a fruiting shrub native to tropical and subtropical countries around the world and cultivated in many...
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Pasteurized form of a potential probiotic lactobacillus brevis IBRC-M10790 exerts anti-inflammatory effects on inflammatory bowel disease in vitro
BackgroundInflammatory bowel disease (IBD) is a chronic, relapsing inflammatory disorder of the gastrointestinal system. So far, no treatment has...
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Rosa × damascena Herrm. From Azaran region, Kashan: rich in saturated and unsaturated fatty acids with inhibitory effect against Proteus mirabilis
BackgroundOne of the most widely used medicinal plants in Iranian traditional medicine, Rosa × damascena Herrm. (mohammadi flower) that the people...
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Effects and mechanisms of puerarin against neuroblastoma: insights from bioinformatics and in vitro experiments
BackgroundNeuroblastoma, a prevalent solid tumor in children, often manifests with hidden onset sites, rapid growth, and high metastatic potential....
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Standard medical ethnobotany of Kohistan, North Pakistan
BackgroundThis study was exclusively focused on the documentation and cross-cultural evaluation of ethnomedicinal knowledge (EMK) within the diverse...
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Application of 3D bioprinting technology apply to assessing Dangguiniantongtang (DGNT) decoctions in arthritis
The aim of this study was to develop a three-dimensional (3D) cell model in order to evaluate the effectiveness of a traditional Chinese medicine...
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Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse
BackgroundAlzheimer's disease (AD) is a common type of dementia characterized by amyloid-β (Aβ) accumulation, lysosomal dysfunction, and tau...
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The effect of Cuminum cyminum on the return of bowel motility after abdominal surgery: a triple-blind randomized clinical trial
Background and objectivesConsidering the significant prevalence of ileus after abdominal surgery and the beneficial effects of Cuminum cyminum in...