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Handbook of Scan Statistics
Scan statistics, one of the most active research areas in applied probability and statistics, has seen a tremendous growth during the last 25 years....
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Globalisation and Official Statistics
Questions of globalisation in connection with official statistics are discussed both from a methodological and empirical point of view. The increase...
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Drug Studies: Using Statistics to Achieve the Optimal Dose
Only few potential drugs pass clinical trials and become approved. With better statistical methods for determining the optimal dose, the number of...
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Discussion on On the role of data, statistics and decisions in a pandemic
The authors make an important contribution presenting a comprehensive and thoughtful overview about the many different aspects of data, statistics...
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Is there a role for statistics in artificial intelligence?
The research on and application of artificial intelligence (AI) has triggered a comprehensive scientific, economic, social and political discussion....
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The Australian Pharmaceutical Benefits Scheme (PBS) Dispensing Database
The Australian Pharmaceutical Benefits Scheme (PBS) database is a routinely collected, whole-of-population collection comprising data on the...
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Pharmaceutical Statistics MBSW 39, Muncie, Indiana, USA, May 16-18, 2016
This book presents the proceedings of the 39th annual Midwest Biopharmaceutical Statistics Workshop (MBSW), held in Muncie, Indiana on May 16–18,...
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On the role of data, statistics and decisions in a pandemic
A pandemic poses particular challenges to decision-making because of the need to continuously adapt decisions to rapidly changing evidence and...
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Handbook of Scan Statistics
Scan statistics, one of the most active research areas in applied probability and statistics, has seen a tremendous growth during the last 25 years....
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Introduction
Probability and statistics are two branches of mathematics while probability deals with the laws governing random events, statistics encompasses...
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Statistics in Clinical and Observational Vaccine Studies
This book offers an overview of the statistical methods used in clinical and observational vaccine studies. Pursuing a practical rather than...
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Genomics and Bioinformatics in Biological Discovery and Pharmaceutical Development
Bioinformatics is a term coined from the 1970s but, like other adaptive systems, has evolved in its scope and utility. Currently its domain includes...
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Quality by Design
Quality is largely determined by decisions made in the early planning phases of products and processes. A particularly powerful technique for making...
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Ireland’s Miraculous Economic Growth
The reason for the description of Ireland’s miraculous economic growth in 2015 was the astonishment of many observers that a statistical office such...
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Basic Statistics
In this chapter, we focus on some basic examples in Probability and Statistics. We phrase these concepts using the language and definitions we have...
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Evolution of Clinical Trials Science
The art of medicine took two millennia to establish the necessary groundwork for clinical trials which embody the scientific method for making fair...
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Power Calculations and Critical Values for Two-Stage Nonparametric Testing Regimes
Interim analysis techniques for clinical trials provide improved power with smaller average sample sizes. These techniques crucially require...
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Real world data and data science in medical research: present and future
Real world data (RWD) are generating greater interest in recent times despite being not new. There are various purposes of the RWD analytics in...
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Equivalence tests for the difference of two survival functions under the class of Box–Cox transformation model
Establishing equivalence of two treatments has received a lot attention in the pharmaceutical industry. For assessing equivalence of two survival...
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Digitalization and a Pandemic
One characteristic of good governance is that political decisions are evidence-based. Facts and figures, with their scientific and technical nature,...