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Melatonin, Circadian Rhythms, and Sleep: An Opportunity to Understand Mechanisms for Protecting Against Neurodegenerative Disease in Drosophila
Research on melatonin’s antioxidant and sleep-chronobiotic properties has increased exponentially over the past 15 years. Resolving the evolutionary...
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Non-communicable disease risk reduction training for medical graduates in India: context, challenges and opportunities
Physicians’ hold pivotal roles in improving non-communicable diseases (NCDs). Studies conducted in India revealed that physicians’ feel unprepared to...
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Spatiotemporal Analysis of Cardiovascular Disease Mortality with Geographical Information Systems
In the world, cardiovascular diseases (CVD) are known as the type of disease with the highest mortality. The mortality rate for this disease is very...
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The Burden of Arteriosclerotic Cardiovascular Disease in Ancient Populations
Arteriosclerosis and cardiovascular diseases (CVDs) are chronic inflammatory afflictions of the vascular system leading to stiffening and occlusion...
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CircRNA and Ageing
Circular RNAs (circRNAs) are closed-loop RNA transcripts formed by a noncanonical back splicing mechanism. circRNAs are expressed in various tissues...
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Cardiovascular Risk Factors in Centenarians
Centenarians are a heterogeneous group of individuals for whom evidence-based clinical treatment guidelines may not apply. These oldest of adults are...
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Fibrinogen, Coagulation, and Ageing
The World Health Organization estimates that the world’s population over 60 years of age will nearly double in the next 30 years. This change imposes...
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Gap Junctions and Ageing
Gap junctions, comprising connexin proteins, create conduits directly coupling the cytoplasms of adjacent cells. Expressed in essentially all...
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Economic gains of transitioning towards reduced-risk products: evidence from Mexico
Unhealthy behaviors such as poor diet and tobacco use contribute to disease burden and escalating healthcare costs. This paper evaluates potential...
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Investigating Potential Gender-Based Differential Item Functioning for Items in the Kansas City Cardiomyopathy Questionnaire (KCCQ) Physical Limitations Domain
Women with heart failure report worse health-related quality of life on average, than men. This may result from actual differences in care or...
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Clinical Ageing
Ageing is generally characterised by the declining ability to respond to stress, increasing homeostatic...
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Practice: Heuristics and Hermeneutics in Data Science
This chapter examines the rhetorical work of analytics and its product, quantitative metrics, as a constructive strategy of intention. This chapter...
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How Depression Arises: A Sociological Questioning and a Methodological Reflection
The World Health Organization issued a warning to all countries in its 2000 “Global Burden of Diseases” report, stating that depression will rank...
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Evolution Today and Tomorrow
The study of human evolution should teach us that we are unusual primates, but not exceptional. We are subject to the same natural laws and...
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Extracellular Vesicles and Cellular Ageing
Ageing is a complex process characterized by deteriorated performance at multiple levels, starting from cellular dysfunction to organ degeneration....
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A Comparative Analysis of Health Expectancy in Central Asia and Russia: Negative- and Positive-Health Approach
Existing research has investigated health expectancy in the former Soviet countries, but health in that research is defined only by physical health...
