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A single point mutation expands the applicability of ostreolysin A6 in biomedicine
An aegerolysin protein ostreolysin A6 (OlyA6) binds to cholesterol-complexed sphingomyelin and can be used for specific labelling of lipid rafts. In...
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Engrained with modernity: commodification, medicalisation, and cross-border medical travel for health care in Nepal
Biomedicine was introduced in Nepal by Christian Missionaries en route to Tibet and China. When Nepal entered the democratic era in the early 60s, a...
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BrainSwarming, blockchain, and bioethics: applying Innovation Enhancing Techniques to healthcare and research
Innovation in healthcare and biomedicine is in decline, yet there exist no widely-known alternatives to traditional brainstorming that can be...
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‘The window of opportunity is closing’—advocating urgency and unity
Science and science policy are characterised by expectations. These expectations—as in the field of biomedicine—may be related to describing novel...
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Clinical performance and utility of a noninvasive urine-based methylation biomarker: TWIST1/Vimentin to detect urothelial carcinoma of the bladder
Traditional clinical modalities for diagnosing bladder urothelial carcinoma (BUC) remain limited due to their invasive nature, significant costs,...
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Zero-field J-spectroscopy of quadrupolar nuclei
Zero- to ultralow-field nuclear magnetic resonance (ZULF NMR) allows molecular structure elucidation via measurement of electron-mediated spin-spin J -...
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Producing knowledge in a pandemic: Accounts from UK-based postdoctoral biomedical scientists of undertaking research during the COVID-19 pandemic
While far from the first pandemic to impact knowledge-production, the widely constructed singularity of the biosocial ramifications of the SARS-CoV-2...
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Bioactive silver nanoparticles fabricated using Lasiurus scindicus and Panicum turgidum seed extracts: anticancer and antibacterial efficiency
Applying extracts from plants is considered a safe approach in biomedicine and bio-nanotechnology. The present report is considered the first study...
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Evolutionary design of explainable algorithms for biomedical image segmentation
An unresolved issue in contemporary biomedicine is the overwhelming number and diversity of complex images that require annotation, analysis and...
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A comprehensive benchmarking with interpretation and operational guidance for the hierarchy of topologically associating domains
Topologically associating domains (TADs), megabase-scale features of chromatin spatial architecture, are organized in a domain-within-domain TAD...
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Open source and reproducible and inexpensive infrastructure for data challenges and education
Data sharing is necessary to maximize the actionable knowledge generated from research data. Data challenges can encourage secondary analyses of...
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Real-time complex light field generation through a multi-core fiber with deep learning
The generation of tailored complex light fields with multi-core fiber (MCF) lensless microendoscopes is widely used in biomedicine. However, the...
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Potential toxicity of graphene (oxide) quantum dots via directly covering the active site of anterior gradient homolog 2 protein
Graphene quantum dots (GQDs) have attracted significant attention in biomedicine, while extensive investigations have revealed a reverse regarding...
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Ultrafast light-activated polymeric nanomotors
Synthetic micro/nanomotors have been extensively exploited over the past decade to achieve active transportation. This interest is a result of their...
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Classification performance assessment for imbalanced multiclass data
The evaluation of diagnostic systems is pivotal for ensuring the deployment of high-quality solutions, especially given the pronounced...
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Impact of Tamm plasmon structures on fluorescence and optical nonlinearity of graphene quantum dots
Graphene Quantum Dots (GQDs) are crucial in biomedicine for sensitive biosensing and high-resolution bioimaging and in photonics for their nonlinear...
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Adaptive constraints by morphological operations for single-shot digital holography
Digital holography provides access to quantitative measurement of the entire complex field, which is indispensable for the investigation of...
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Angle-programmed tendril-like trajectories enable a multifunctional gripper with ultradelicacy, ultrastrength, and ultraprecision
Achieving multicapability in a single soft gripper for handling ultrasoft, ultrathin, and ultraheavy objects is challenging due to the tradeoff...
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A bioinspired surface tension-driven route toward programmed cellular ceramics
The intriguing biomineralization process in nature endows the mineralized biological materials with intricate microarchitected structures in a facile...
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Generic prediction of exocytosis rate constants by size-based surface energies of nanoparticles and cells
Nanotechnology brings benefits in fields such as biomedicine but nanoparticles (NPs) may also have adverse health effects. The effects of...