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Stem water potential estimation from images using a field noise-robust deep regression-based approach in peach trees
Field-grown peach trees are large and have a complex branch structure; therefore, detection of water deficit stress from images is challenging. We...
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Machine learning discriminates P2X7-mediated intracellular calcium sparks in human-induced pluripotent stem cell-derived neural stem cells
Adenosine triphosphate (ATP) is an extracellular signaling molecule that mainly affects the pathophysiological situation in the body and can be...
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Assessing the distribution of cancer stem cells in tumorspheres
Cancer Stem Cells presumably drive tumor growth and resistance to conventional cancer treatments. From a previous computational model, we inferred...
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Online images amplify gender bias
Each year, people spend less time reading and more time viewing images
1 , which are proliferating online2 –4 . Images from platforms such as Google and... -
Iterative pseudo balancing for stem cell microscopy image classification
Many critical issues arise when training deep neural networks using limited biological datasets. These include overfitting, exploding/vanishing...
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Human archetypal pluripotent stem cells differentiate into trophoblast stem cells via endogenous BMP5/7 induction without transitioning through naive state
Primary human trophoblast stem cells (TSCs) and TSCs derived from human pluripotent stem cells (hPSCs) can potentially model placental processes in...
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Embryonic-stem-cell-derived mesenchymal stem cells relieve experimental contact urticaria by regulating the functions of mast cells and T cells
Contact urticaria (CU) is an inflammatory skin disorder triggered by specific substances upon skin contact, leading to immediate acute or chronic...
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A comparative analysis of pairwise image stitching techniques for microscopy images
Stitching of microscopic images is a technique used to combine multiple overlap** images (tiles) from biological samples with a limited field of...
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An advanced fast method for the evaluation of multiple immunolabelling using gold nanoparticles based on low-energy STEM
We present a powerful method for the simultaneous detection of Au nanoparticles located on both sides of ultrathin sections. The method employs a...
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Diffusible fraction of niche BMP ligand safeguards stem-cell differentiation
Drosophila male germline stem cells (GSCs) reside at the tip of the testis and surround a cluster of niche cells. Decapentaplegic (Dpp) is one of the...
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Periosteal stem cells control growth plate stem cells during postnatal skeletal growth
The ontogeny and fate of stem cells have been extensively investigated by lineage-tracing approaches. At distinct anatomical sites, bone tissue...
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Fate specification is spatially intermingled across planarian stem cells
Regeneration requires mechanisms for producing a wide array of cell types. Neoblasts are stem cells in the planarian Schmidtea mediterranea that...
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Fast and robust feature-based stitching algorithm for microscopic images
The limited field of view of high-resolution microscopic images hinders the study of biological samples in a single shot. Stitching of microscope...
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Airway hillocks are injury-resistant reservoirs of unique plastic stem cells
Airway hillocks are stratified epithelial structures of unknown function
1 . Hillocks persist for months and have a unique population of basal stem... -
Quiescence enables unrestricted cell fate in naive embryonic stem cells
Quiescence in stem cells is traditionally considered as a state of inactive dormancy or with poised potential. Naive mouse embryonic stem cells...
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A multi-stem cell basis for craniosynostosis and calvarial mineralization
Craniosynostosis is a group of disorders of premature calvarial suture fusion. The identity of the calvarial stem cells (CSCs) that produce...
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ROR2 expression predicts human induced pluripotent stem cell differentiation into neural stem/progenitor cells and GABAergic neurons
Despite the development of various in vitro differentiation protocols for the efficient derivation of specific cell types, human induced pluripotent...
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Dedifferentiation maintains melanocyte stem cells in a dynamic niche
For unknow reasons, the melanocyte stem cell (McSC) system fails earlier than other adult stem cell populations
1 , which leads to hair greying in most... -
A vertebral skeletal stem cell lineage driving metastasis
Vertebral bone is subject to a distinct set of disease processes from long bones, including a much higher rate of solid tumour metastases
1 –4 . The... -
Stem cells derived exosomes as biological nano carriers for VCR sulfate for treating breast cancer stem cells
Due to vincristine sulfate’s (VCR sulfate) toxicity and non-specific targeting, which might adversely damage healthy cells, its clinical application...