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  1. Stem water potential estimation from images using a field noise-robust deep regression-based approach in peach trees

    Field-grown peach trees are large and have a complex branch structure; therefore, detection of water deficit stress from images is challenging. We...

    Takayoshi Yamane, Harshana Habaragamuwa, ... Nobuhito Mitani in Scientific Reports
    Article Open access 15 December 2023
  2. Machine learning discriminates P2X7-mediated intracellular calcium sparks in human-induced pluripotent stem cell-derived neural stem cells

    Adenosine triphosphate (ATP) is an extracellular signaling molecule that mainly affects the pathophysiological situation in the body and can be...

    Yuki Hanafusa, Akira Shiraishi, Fumiyuki Hattori in Scientific Reports
    Article Open access 04 August 2023
  3. Assessing the distribution of cancer stem cells in tumorspheres

    Cancer Stem Cells presumably drive tumor growth and resistance to conventional cancer treatments. From a previous computational model, we inferred...

    Jerónimo Fotinós, María Paula Marks, ... Luciano Vellón in Scientific Reports
    Article Open access 14 May 2024
  4. Online images amplify gender bias

    Each year, people spend less time reading and more time viewing images 1 , which are proliferating online 2 4 . Images from platforms such as Google and...

    Douglas Guilbeault, Solène Delecourt, ... Ethan Nadler in Nature
    Article Open access 14 February 2024
  5. Iterative pseudo balancing for stem cell microscopy image classification

    Many critical issues arise when training deep neural networks using limited biological datasets. These include overfitting, exploding/vanishing...

    Adam Witmer, Bir Bhanu in Scientific Reports
    Article Open access 24 February 2024
  6. Human archetypal pluripotent stem cells differentiate into trophoblast stem cells via endogenous BMP5/7 induction without transitioning through naive state

    Primary human trophoblast stem cells (TSCs) and TSCs derived from human pluripotent stem cells (hPSCs) can potentially model placental processes in...

    Ethan Tietze, Andre Rocha Barbosa, ... Jennifer A. Erwin in Scientific Reports
    Article Open access 08 February 2024
  7. Embryonic-stem-cell-derived mesenchymal stem cells relieve experimental contact urticaria by regulating the functions of mast cells and T cells

    Contact urticaria (CU) is an inflammatory skin disorder triggered by specific substances upon skin contact, leading to immediate acute or chronic...

    Seung Yeun Hyun, Eun-Young Kim, ... Hyuk Soon Kim in Scientific Reports
    Article Open access 20 December 2023
  8. A comparative analysis of pairwise image stitching techniques for microscopy images

    Stitching of microscopic images is a technique used to combine multiple overlap** images (tiles) from biological samples with a limited field of...

    Fatemeh Sadat Mohammadi, Seyyed Erfan Mohammadi, ... Hasti Shabani in Scientific Reports
    Article Open access 22 April 2024
  9. An advanced fast method for the evaluation of multiple immunolabelling using gold nanoparticles based on low-energy STEM

    We present a powerful method for the simultaneous detection of Au nanoparticles located on both sides of ultrathin sections. The method employs a...

    František Kitzberger, Shun-Min Yang, ... Jana Nebesářová in Scientific Reports
    Article Open access 02 May 2024
  10. Diffusible fraction of niche BMP ligand safeguards stem-cell differentiation

    Drosophila male germline stem cells (GSCs) reside at the tip of the testis and surround a cluster of niche cells. Decapentaplegic (Dpp) is one of the...

    Sharif M. Ridwan, Autumn Twillie, ... Mayu Inaba in Nature Communications
    Article Open access 07 February 2024
  11. Periosteal stem cells control growth plate stem cells during postnatal skeletal growth

    The ontogeny and fate of stem cells have been extensively investigated by lineage-tracing approaches. At distinct anatomical sites, bone tissue...

    Masayuki Tsukasaki, Noriko Komatsu, ... Hiroshi Takayanagi in Nature Communications
    Article Open access 18 July 2022
  12. Fate specification is spatially intermingled across planarian stem cells

    Regeneration requires mechanisms for producing a wide array of cell types. Neoblasts are stem cells in the planarian Schmidtea mediterranea that...

    Chanyoung Park, Kwadwo E. Owusu-Boaitey, ... Peter W. Reddien in Nature Communications
    Article Open access 16 November 2023
  13. Fast and robust feature-based stitching algorithm for microscopic images

    The limited field of view of high-resolution microscopic images hinders the study of biological samples in a single shot. Stitching of microscope...

    Fatemeh Sadat Mohammadi, Hasti Shabani, Mojtaba Zarei in Scientific Reports
    Article Open access 10 June 2024
  14. Airway hillocks are injury-resistant reservoirs of unique plastic stem cells

    Airway hillocks are stratified epithelial structures of unknown function 1 . Hillocks persist for months and have a unique population of basal stem...

    Brian Lin, Viral S. Shah, ... Jayaraj Rajagopal in Nature
    Article 01 May 2024
  15. Quiescence enables unrestricted cell fate in naive embryonic stem cells

    Quiescence in stem cells is traditionally considered as a state of inactive dormancy or with poised potential. Naive mouse embryonic stem cells...

    Le Tran Phuc Khoa, Wentao Yang, ... Yali Dou in Nature Communications
    Article Open access 26 February 2024
  16. A multi-stem cell basis for craniosynostosis and calvarial mineralization

    Craniosynostosis is a group of disorders of premature calvarial suture fusion. The identity of the calvarial stem cells (CSCs) that produce...

    Seoyeon Bok, Alisha R. Yallowitz, ... Matthew B. Greenblatt in Nature
    Article 20 September 2023
  17. ROR2 expression predicts human induced pluripotent stem cell differentiation into neural stem/progenitor cells and GABAergic neurons

    Despite the development of various in vitro differentiation protocols for the efficient derivation of specific cell types, human induced pluripotent...

    Takuya Kuroda, Satoshi Yasuda, ... Yoji Sato in Scientific Reports
    Article Open access 06 January 2024
  18. Dedifferentiation maintains melanocyte stem cells in a dynamic niche

    For unknow reasons, the melanocyte stem cell (McSC) system fails earlier than other adult stem cell populations 1 , which leads to hair greying in most...

    Qi Sun, Wendy Lee, ... Mayumi Ito in Nature
    Article Open access 19 April 2023
  19. A vertebral skeletal stem cell lineage driving metastasis

    Vertebral bone is subject to a distinct set of disease processes from long bones, including a much higher rate of solid tumour metastases 1 4 . The...

    Jun Sun, Lingling Hu, ... Matthew B. Greenblatt in Nature
    Article 13 September 2023
  20. Stem cells derived exosomes as biological nano carriers for VCR sulfate for treating breast cancer stem cells

    Due to vincristine sulfate’s (VCR sulfate) toxicity and non-specific targeting, which might adversely damage healthy cells, its clinical application...

    Ahmed H. Farouk, Ahmed Aref, ... Ahmed N. Abdallah in Scientific Reports
    Article Open access 14 May 2024
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