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Priority age targets for COVID-19 vaccination in Ethiopia under limited vaccine supply
The worldwide inequitable access to vaccination claims for a re-assessment of policies that could minimize the COVID-19 burden in low-income...
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**ing the brain to reveal the hidden attentional priority map using encephalography
Attention has been usefully thought of as organized in priority maps – putative maps of space where attentional priority is weighted across spatial...
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Priority areas to protect mangroves and maximise ecosystem services
Anthropogenic activities threaten global biodiversity and ecosystem services. Yet, area-based conservation efforts typically target biodiversity...
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Multi-objective predictive control based on the cutting tobacco outlet moisture priority
In this paper, we propose a new priority multi-objective optimization strategy of system output variables in cutting tobacco process. The proposed...
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Discovery of immunotherapy targets for pediatric solid and brain tumors by exon-level expression
Immunotherapy with chimeric antigen receptor T cells for pediatric solid and brain tumors is constrained by available targetable antigens....
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The factors affecting the performance of the tunnel wall drilling task and their priority
Clarifying the relationship between the man–machine environment and its impact on the tunnel wall drilling task performance (TWDTP) is crucial for...
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In-silico identification and prioritization of therapeutic targets of asthma
Asthma is a “common chronic disorder that affects the lungs causing variable and recurring symptoms like repeated episodes of wheezing,...
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Alkyl deoxyglycoside-polymyxin combinations against critical priority carbapenem-resistant gram-negative bacteria
The escalating antimicrobial resistance crisis urges the development of new antibacterial treatments with innovative mechanisms of action,...
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A publication-wide association study (PWAS), historical language models to prioritise novel therapeutic drug targets
Most biomedical knowledge is published as text, making it challenging to analyse using traditional statistical methods. In contrast,...
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Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure
We conduct a large-scale meta-analysis of heart failure genome-wide association studies (GWAS) consisting of over 90,000 heart failure cases and more...
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An agenda for future Social Sciences and Humanities research on energy efficiency: 100 priority research questions
Decades of techno-economic energy policymaking and research have meant evidence from the Social Sciences and Humanities (SSH)—including critical...
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Global priority areas for ecosystem restoration
Extensive ecosystem restoration is increasingly seen as being central to conserving biodiversity
1 and stabilizing the climate of the Earth2 . Although...
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Cross species systems biology discovers glial DDR2, STOM, and KANK2 as therapeutic targets in progressive supranuclear palsy
Progressive supranuclear palsy (PSP) is a neurodegenerative parkinsonian disorder characterized by cell-type-specific tau lesions in neurons and...
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In silico analysis of SARS-CoV-2 proteins as targets for clinically available drugs
The ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) requires treatments with rapid clinical translatability....
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Map** Wetland Ecosystems Protection and Restoration Priority Using GIS, Remote Sensing, Landscape Ecology, and Multi-criteria Analysis (Case Study in Dong Thap Muoi)
The prioritisation of wetland ecosystems is the essential information contributing to scientific and methodological fundamentals for establishing the...
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Potential therapeutic targets of gastric cancer explored under endogenous network modeling of clinical data
Improvement in the survival rate of gastric cancer, a prevalent global malignancy and the leading cause of cancer-related mortality calls for more...
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Geospatial characterization of rural settlements and potential targets for revitalization by geoinformation technology
To better implement the Strategy of Rural Revitalization, it is essential to characterize the rural settlements and understand their roles in the...
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A bolder conservation future for Indonesia by prioritising biodiversity, carbon and unique ecosystems in Sulawesi
As more ambitious protected area (PA) targets for the post-2020 global biodiversity framework are set beyond Aichi Target 11, renew thinking into...
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Integrated guidance and control design by active disturbance rejection method for high-velocity target interceptor with DCS thruster
The present paper proposes a novel integrated guidance and control (IGC) method for engaging with high-speed targets such as ballistic projectiles....
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Transcriptional targets of senataxin and E2 promoter binding factors are associated with neuro-degenerative pathways during increased autophagic flux
Autophagy is an intracellular recycling process that degrades harmful molecules and enables survival during starvation, with implications for...
