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Mirabegron displays anticancer effects by globally browning adipose tissues
Metabolic reprogramming in malignant cells is a hallmark of cancer that relies on augmented glycolytic metabolism to support their growth, invasion,...
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Joining up the scattered anticancer knowledge on auraptene and umbelliprenin: a meta-analysis
Auraptene (AUR) and umbelliprenin (UMB) are naturally occurring prenylated coumarins that have demonstrated promising anticancer effects across...
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Design, synthesis and in vitro anticancer activity of some new lomefloxacin derivatives
Our main goal was to design and synthesize novel lomefloxacin derivatives that inhibit the topoisomerase II enzyme, leading to potent anticancer...
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Study of some graph theoretical parameters for the structures of anticancer drugs
Eigenvalues have great importance in the field of mathematics, and their relevance extends beyond this area to include several other disciplines such...
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ApInAPDB: a database of apoptosis-inducing anticancer peptides
ApInAPDB (Apoptosis-Inducing Anticancer Peptides Database) consists of 818 apoptosis-inducing anticancer peptides which are manually collected from...
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Anticancer efficacy of biosynthesized silver nanoparticles loaded with recombinant truncated parasporin-2 protein
Bacterial toxins have received a great deal of attention in the development of cancer treatments. Parasporin-2 (PS2Aa1 or Mpp46Aa1) is a Bacillus...
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Anticancer potential of thiocolchicoside and lauric acid loaded chitosan nanogel against oral cancer cell lines: a comprehensive study
The present study explored the anticancer activity of a Chitosan-based nanogel incorporating thiocolchicoside and lauric acid (CTL) against oral...
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Design, synthesis and anticancer activities evaluation of novel pyrazole modified catalpol derivatives
Catalpol, a natural product mainly existed in plenty of Chinese traditional medicines, is an iridoid compound with the comprehensive effects on...
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Mechanisms involved in the anticancer effects of sinapic acid
BackgroundCancer refers to a group of diseases characterized by the development of abnormal cells that divide uncontrollably and have the ability to...
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Novel pyridine bearing pentose moiety-based anticancer agents: design, synthesis, radioiodination and bioassessments
Pyridine compounds are one of the most important heterocyclic derivatives showing wide ranges in biological and pharmacological activities. Green...
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1,2,3-triazole and chiral Schiff base hybrids as potential anticancer agents: DFT, molecular docking and ADME studies
A series of novel 1,2,3-triazole and chiral Schiff base hybrids 2 – 6 were synthesized by Schiff base condensation reaction from pre-prepared parent...
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Biosynthesis of palladium, platinum, and their bimetallic nanoparticles using rosemary and ginseng herbal plants: evaluation of anticancer activity
In this research, palladium (II) and platinum (II), as well as their bimetallic nanoparticles were synthesized using medicinal plants in an...
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Green synthesis of silver nanoparticle prepared with Ocimum species and assessment of anticancer potential
Silver nanoparticles (AgNPs) have gained much attention due to their unique physical, and chemical properties. Integration of phytochemicals in...
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Novel quinazoline-1,2,3-triazole hybrids with anticancer and MET kinase targeting properties
Oncogenic activation of receptor tyrosine kinases (RTKs) such as MET is associated with cancer initiation and progression. We designed and...
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In vitro anticancer potential of laminarin and fucoidan from Brown seaweeds
Marine seaweeds are rich source of polysaccharides present in their cell wall and are cultivated and consumed in China, Japan, Korea, and South Asian...
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The anticancer and antibacterial potential of bioactive secondary metabolites derived From bacterial endophytes in association with Artemisia absinthium
The continuous search for secondary metabolites in microorganisms isolated from untapped reservoirs is an effective prospective approach to drug...
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DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors
Role of DNA damage and demethylation on anticancer activity of DNA methyltransferase inhibitors (DNMTi) remains undefined. We report the effects of DNMT1...
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Discovery of 1-(5-bromopyrazin-2-yl)-1-[3-(trifluoromethyl)benzyl]urea as a promising anticancer drug via synthesis, characterization, biological screening, and computational studies
Cancer and different types of tumors are still the most resistant diseases to available therapeutic agents. Finding a highly effective anticancer...
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Cholesterol-stabilized membrane-active nanopores with anticancer activities
Cholesterol-enhanced pore formation is one evolutionary means cholesterol-free bacterial cells utilize to specifically target cholesterol-rich...
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ACPred-BMF: bidirectional LSTM with multiple feature representations for explainable anticancer peptide prediction
Cancer has become a major factor threatening human life and health. Under the circumstance that traditional treatment methods such as chemotherapy...
