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Ketamine’s acute effects on negative brain states are mediated through distinct altered states of consciousness in humans
Ketamine commonly and rapidly induces dissociative and other altered states of consciousness (ASCs) in humans. However, the neural mechanisms that...
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Induction of altered states of consciousness during Floatation-REST is associated with the dissolution of body boundaries and the distortion of subjective time
Floatation-REST (Reduced Environmental Stimulation Therapy) minimizes stimulation of the nervous system by immersing subjects in an environment...
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Quantifying arousal and awareness in altered states of consciousness using interpretable deep learning
Consciousness can be defined by two components: arousal (wakefulness) and awareness (subjective experience). However, neurophysiological...
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Hierarchical fluctuation shapes a dynamic flow linked to states of consciousness
Consciousness arises from the spatiotemporal neural dynamics, however, its relationship with neural flexibility and regional specialization remains...
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Autonomic nervous system modulation during self-induced non-ordinary states of consciousness
Self-induced cognitive trance (SICT) is a voluntary non-ordinary state of consciousness characterized by a lucid yet narrowed awareness of the...
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The Altered States Database: Psychometric data from a systematic literature review
In this paper, we present the development of the Altered States Database (ASDB), an open-science project based on a systematic literature review. The...
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Functional geometry of the cortex encodes dimensions of consciousness
Consciousness is a multidimensional phenomenon, but key dimensions such as awareness and wakefulness have been described conceptually rather than...
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Consciousness alteration in focal epilepsy is related to loss of signal complexity and information processing
Alteration of awareness is a main feature of focal epileptic seizures. In this work, we studied how the information contained in EEG signals was...
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Local orchestration of distributed functional patterns supporting loss and restoration of consciousness in the primate brain
A central challenge of neuroscience is to elucidate how brain function supports consciousness. Here, we combine the specificity of focal deep brain...
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Central autonomic network and early prognosis in patients with disorders of consciousness
The central autonomic network (CAN) plays a crucial role in modulating the autonomic nervous system. Heart rate variability (HRV) is a valuable...
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Deep brain stimulation in disorders of consciousness: 10 years of a single center experience
Disorders of consciousness (DoC), namely unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS), represent severe conditions...
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Reversed and increased functional connectivity in non-REM sleep suggests an altered rather than reduced state of consciousness relative to wake
Sleep resting state network (RSN) functional connectivity (FC) is poorly understood, particularly for rapid eye movement (REM), and in non-sleep...
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The multimodal Ganzfeld-induced altered state of consciousness induces decreased thalamo-cortical coupling
Different pharmacologic agents have been used to investigate the neuronal underpinnings of alterations in consciousness states, such as psychedelic...
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Neuronal connected burst cascades bridge macroscale adaptive signatures across arousal states
The human brain displays a rich repertoire of states that emerge from the microscopic interactions of cortical and subcortical neurons. Difficulties...
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Reorganisation of Brain Hubs across Altered States of Consciousness
Patterns of functional interactions across distributed brain regions are suggested to provide a scaffold for the conscious processing of information,...
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Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures
Absence seizures are brief episodes of impaired consciousness, behavioral arrest, and unresponsiveness, with yet-unknown neuronal mechanisms. Here we...
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The role of bodily self-consciousness in episodic memory of naturalistic events: an immersive virtual reality study
Recent studies suggest that the human body plays a critical role in episodic memory. Still, the precise relationship between bodily...
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Brain network motifs are markers of loss and recovery of consciousness
Motifs are patterns of inter-connections between nodes of a network, and have been investigated as building blocks of directed networks. This study...
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The bodily self from psychosis to psychedelics
The sense of self is a foundational element of neurotypical human consciousness. We normally experience the world as embodied agents, with the...
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Subcortical-cortical dynamical states of the human brain and their breakdown in stroke
The mechanisms controlling dynamical patterns in spontaneous brain activity are poorly understood. Here, we provide evidence that cortical dynamics...
