Search
Search Results
-
The interaction of mast cells with membranes from lung cancer cells induces the release of extracellular vesicles with a unique miRNA signature
Mast cells (MCs) are immune cells that play roles in both normal and abnormal processes. They have been linked to tumor progression in several types...
-
Excess PrPC inhibits muscle cell differentiation via miRNA-enhanced liquid–liquid phase separation implicated in myopathy
The cellular prion protein (PrP C ) is required for skeletal muscle function. Here, we report that a higher level of PrP C accumulates in the cytoplasm...
-
Clinical significance of urinary exosomal microRNAs in patients with IgA nephropathy
Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis worldwide. The clinical relevance of 11 urinary exosomal microRNAs...
-
Plasma microRNA ratios associated with breast cancer detection in a nested case–control study from a mammography screening cohort
Mammographic breast cancer screening is effective in reducing breast cancer mortality. Nevertheless, several limitations are known. Therefore,...
-
Identification and profiling of microRNAs expressed in oral buccal mucosa squamous cell carcinoma of Chinese hamster
MicroRNAs are known to play essential role in the gene expression regulation in cancer. In our research, next-generation sequencing technology was...
-
Circulating exosomal miR-16-5p and let-7e-5p are associated with bladder fibrosis of diabetic cystopathy
Diabetic cystopathy (DCP) is a prevalent etiology of bladder dysfunction in individuals with longstanding diabetes, frequently leading to bladder...
-
Optimized RT-qPCR and a novel normalization method for validating circulating miRNA biomarkers in ageing-related diseases
Circulating miRNAs have potential as minimally invasive biomarkers for diagnosing various diseases, including ageing-related disorders such as...
-
miRNA profiling as a complementary diagnostic tool for amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS), the most prevalent motor neuron disease characterized by its complex genetic structure, lacks a single...
-
Expression status of circ-SMARCA5, circ-NOL10, circ-LDLRAD3, and circ-RHOT1 in patients with colorectal cancer
Colorectal cancer (CRC) poses a significant burden on both the healthcare systems as well as individuals. The high mortality rate of CRC may be...
-
Early to sustained impacts of lethal radiation on circulating miRNAs in a minipig model
Early diagnosis of lethal radiation is imperative since its intervention time windows are considerably short. Hence, ideal diagnostic candidates of...
-
Serum exosomal microRNA-1258 may as a novel biomarker for the diagnosis of acute exacerbations of chronic obstructive pulmonary disease
Acute exacerbation chronic obstructive pulmonary disease (AECOPD) has a high mortality rate. However, there is no efficiency biomarker for diagnosing...
-
Discovering therapeutic possibilities for polycystic ovary syndrome by targeting XIST and its associated ceRNA network through the analysis of transcriptome data
Long non-coding RNA (lncRNA) regulates many physiological processes by acting as competitive endogenous RNA (ceRNA). The dysregulation of lncRNA...
-
Exercise increases MEF2A abundance in rat cardiac muscle by downregulating microRNA-223-5p
Exercise plays an important role in cardiac health and enhances the transport of glucose in cardiac muscle by increasing the glucose transporter-4...
-
Increased expression of miR-320b in blood plasma of patients in response to SARS-CoV-2 infection
Coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Recent research has demonstrated how...
-
Pinostrobin, a fingerroot compound, regulates miR-181b-5p and induces acute leukemic cell apoptosis
Pinostrobin (PN) is the most abundant flavonoid found in fingerroot. Although the anti-leukemic properties of PN have been reported, its mechanisms...
-
ceRNA network-regulated COL1A2 high expression correlates with poor prognosis and immune infiltration in colon adenocarcinoma
Collagen type I α 2 (COL1A2) is a major component of collagen type I. Recently, abnormal COL1A2 expression has been reported in human cancers....
-
Advanced stage, high-grade primary tumor ovarian cancer: a multi-omics dissection and biomarker prediction process
Ovarian cancer (OC) incidence and mortality rates continue to escalate globally. Early detection of OC is challenging due to extensive metastases and...
-
Integrative genetic and genomic networks identify microRNA associated with COPD and ILD
Chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) are clinically and molecularly heterogeneous diseases. We utilized...
-
Screening of reference genes for microRNA analysis in the study of solider caste differentiation of Formosan subterranean termite Coptotermes formosanus Shiraki
The soldier caste differentiation is a complex process that is governed by the transcriptional regulation and post-transcriptional regulation....
-
Repression of developmental transcription factor networks triggers aging-associated gene expression in human glial progenitor cells
Human glial progenitor cells (hGPCs) exhibit diminished expansion competence with age, as well as after recurrent demyelination. Using RNA-sequencing...
