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Solution-state NMR assignment and secondary structure analysis of the monomeric Pseudomonas biofilm-forming functional amyloid accessory protein FapA
FapA is an accessory protein within the biofilm forming functional bacterial amyloid related fap-operon in Pseudomonas , and maybe a chaperone for...
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Extreme-value analysis of intracellular cargo transport by motor proteins
The mechanisms underlying the chemo-mechanical coupling of motor proteins is usually described by a set of force-velocity relations that reflect the...
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Structure of SARS-CoV-2 Proteins
COVID-19 is a newly emerging infectious disease that currently has been posing great threat to the world. This infectious disease is caused by a...
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Ion currents through the voltage sensor domain of distinct families of proteins
The membrane potential of a cell (V m ) regulates several physiological processes. The voltage sensor domain (VSD) is a region that confers voltage...
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AI Panorama Art of Proteins with Image Blending Deep Learning
Interdisciplinarily weaving science into art, this project aims to highlight both the esthetic beauty of protein structures, as well as the essential...
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Backbone and ILV side-chain methyl NMR resonance assignments of human Rev7/Rev3-RBM1 and Rev7/Rev3-RBM2 complexes
Rev7 is a versatile HORMA (Hop1, Rev7, Mad2) family adaptor protein with multiple roles in mitotic regulation and DNA damage response, and an...
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The Endoplasmic Reticulum: A Central Player in Cell Signalling and Protein Synthesis
In addition to being the principle intracellular Ca 2+ store, the endoplasmic reticulum (ER) is the initial site of synthesis and folding of membrane...
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Regulation of IP 3 Receptors by IP 3 and Ca 2+
Inositol 1,4,5-trisphosphate ( IP 3) receptors are intracellular Ca 2+ channels that mediate release of Ca 2+ from intracellular stores. The channels...
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Evaluation of copper-induced biomolecular changes in different porin mutants of Escherichia coli W3110 by infrared spectroscopy
Copper (Cu), one of the heavy metals, plays a vital role in many complex biochemical reactions as a trace element. However, it often becomes toxic...
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Analysis of SARS-CoV-2 interactions with the Vero cell lines by scanning electron microscopy
In this study, scanning electron microscopy (SEM) was used to study the cell structure of SARS-CoV-2 infected cells. Our measurements revealed...
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Tropism of SARS CoV2
With the knowledge on the structure and functions of SARS CoV2 and the host protein receptor (as discussed in Chap. 2...
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Study of the Mechanism of Interaction of Ficin with a Graft Copolymer of Carboxymethyl Cellulose Sodium Salt and N-vinylimidazole Using Molecular Docking, as Well as Infrared and Raman Spectroscopy
AbstractThe mechanism of interaction of ficin with a graft copolymer of the sodium salt of carboxymethylcellulose and N -vinylimidazole has been...
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The Integrative Approach to Study of the Structure and Functions of Cardiac Voltage-Dependent Ion Channels
AbstractMembrane proteins, including ion channels, became the focus of structural proteomics midway through the 20th century. Methods for studying...
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Infrared microspectroscopy beamline BL06B at SSRF
The infrared microspectroscopy beamline (BL06B) is a phase II beamline project at the Shanghai Synchrotron Radiation Facility (SSRF). The...
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Single-Molecule Fluorescence Imaging of DNA Replication Stalling at Sites of Nucleoprotein Complexes
DNA replication in cells occurs on crowded and often damaged template DNA, forming potentially deleterious roadblocks to the progressing replication...
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1H, 13C, and 15N backbone chemical-shift assignments of SARS-CoV-2 non-structural protein 1 (leader protein)
The current COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has become a worldwide health crisis,...
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Introduction to the Virus and Its Infection Stages
Coronavirus disease 2019 (COVID-19) originated from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which has been affecting numerous...
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Quantifying ATP-Independent Nucleosome Chaperone Activity with Single-Molecule Methods
The dynamics of histone-DNA interactions govern chromosome organization and regulates the processes of transcription, replication, and repair....