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Analysis of the effects of magnetic levitation to simulate microgravity environment on the Arp2/3 complex pathway in macrophage
With dwindling natural resources on earth, current and future generations will need to explore space to new planets that will require travel under no...
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Recombineering and MAGE
Recombination-mediated genetic engineering, also known as recombineering, is the genomic incorporation of homologous single-stranded or...
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Mechanical View on the Endoplasmatic Reticulum and Golgi
This chapter characterizes the most important cellular organellesOrganelles such as the endoplasmatic reticulumEndoplasmatic Reticulum (ER) and the...
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Study of Phenylalanine NIR Spectra for Phenylketonuria Determination
The aim of this study is to investigate the spectroscopic characteristics of phenylalanine in the NIR spectral range as a preliminary step towards...
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Backbone chemical shift assignments for the SARS-CoV-2 non-structural protein Nsp9: intermediate (ms – μs) dynamics in the C-terminal helix at the dimer interface
The Betacoronavirus SARS-CoV-2 non-structural protein Nsp9 is a 113-residue protein that is essential for viral replication, and consequently, a...
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The Cell Nucleus and Its Compartments
This chapter presents the basic knowledge about the function of cell divisionCell division and the cell cycle process. In fine detail, the...
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Bio-microelectromechanical Systems (BioMEMS) in Bio-sensing Applications-Colorimetric Detection Strategies
Colorimetric detection is one of the main strategies used in biosensors due to the inexpensive, rapid, and easy readout. Among the main types of...
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Atom probe tomography
Atom probe tomography (APT) provides three-dimensional compositional map** with sub-nanometre resolution. The sensitivity of APT is in the range of...
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Cell Cycle, DNA Replication, Centrosomes, Centrioles and Cell Division
This chapter deals with the basic knowledge about the function of cell divisionCell division and the entire cell cycle process. More precisely, the...
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Biophysics of RNA-Guided CRISPR Immunity
Prokaryotes are constantly threatened by a large array of viruses and other mobile genetic elements. The evolutionary arms’ race between these...
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Three Persian Qajar paintings from the National Gallery Sofia. Study of the technology and the composition materials for the purpose of dating and conservation evaluation
Three Persian oil paintings on canvas from the collection of the National Gallery, Sofia, representing a Musician playing Daf, Musician playing...
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Complete 1H, 13C, 15N resonance assignments and secondary structure of the Vpr binding region of hHR23A (residues 223–363)
Comprehensive resonance assignments and delineation of the secondary structure elements of the C-terminal Vpr-binding region of hHR23A, residues...
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The Geological Platform for the Origin of Life on Earth
Resolving the geochemical steps which led to the first living organisms on Earth is perhaps one of the most challenging tasks in science. A prime...
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Single Molecule Sensing
The dielectric nanoparties/molecules in the vicinity of a WGM microcavity evanescently perturb the WGM field. Owing to the tiny mode volume and high...
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Single-Molecule Optical Tweezers Studies of Translation
Translation, the process of ribosome-mediated protein synthesis, is a key step for gene expression regulation. Single-molecule optical tweezers...
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A novel combinatorial approach of quantitative microscopy and in silico modeling deciphers Arf1-dependent Golgi size regulation
Abstract.Regulation of organelle size and shape is a poorly understood but fascinating subject. Several theoretical studies were reported on Golgi...
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Cell Proliferation, Survival, Necrosis and Apoptosis
There areFundamental cellular processes fundamental cellular processesCellular processes, such as proliferation, survival, necrosisNecrosis and...
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Identification of H-Bonds in a Calcified Aortic Valve
AbstractThe IR absorption spectra of subendothelial regions of the aortic valve cusps of a patient with calcified aortic stenosis diagnosis were...
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From mechanical resilience to active material properties in biopolymer networks
The cells and tissues that make up our body manage contradictory mechanical demands. It is crucial for their survival to be able to withstand large...
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Lysosomes and Peroxisomes
Besides the major organellesOrganelles of the cell, such as nucleus, mitochondria, EREndoplasmatic Reticulum (ER) and Golgi apparatusGolgi apparatus,...