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Ethical Issues in Genetically Modified Foods: From Transgenesis to CRISPR-Cas9 Genome Editing Technology
Traditional ethical quandaries related to GM foods have been addressed profusely throughout the years. Still, some concerns remain regarding...
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Ethics and Genomic Editing Using the Crispr-Cas9 Technique: Challenges and Conflicts
The field of genetics has seen major advances in recent decades, particularly in research, prevention and diagnosis. One of the most recent...
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A Q methodology study on divergent perspectives on CRISPR-Cas9 in the Netherlands
BackgroundCRISPR-Cas9, a technology enabling modification of the human genome, is develo** rapidly. There have been calls for public debate to...
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CRISPR-Cas9 and He Jiankui's Case: an Islamic Bioethics Review using Maqasid al-Shari'a and Qawaid Fighiyyah
The discovery of clustered regularly interspaced short palindromic repeats (CRISPR) and the CRISPR-mediated protein 9 (CRISPR-Cas9) immediately...
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Learning from Icarus: The Impact of CRISPR on Gene Editing Ethics
After centuries of crude genetic engineering through crossbreeding, the ability to directly intervene in life’s fundamental blueprint led to...
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Adaptive immunity or evolutionary adaptation? Transgenerational immune systems at the crossroads
In recent years, immune systems have sparked considerable interest within the philosophy of science. One issue that has received increased attention...
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Gene Therapy and Germline Cells Research
This chapter is aimed at providing the reader with an overview of the phenomenological complexity created by Gene Therapy and Germline Cell Research...
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Gene Editing Cattle for Enhancing Heat Tolerance: A Welfare Review of the “PRLR-SLICK Cattle” Case
In March 2022 the US Food and Drug Administration (FDA) published a risk assessment of a recent animal gene editing proposal submitted by Acceligen™....
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Bioeconomy and Ethics
Although many empirical studies have been done to elaborate the meaning of sustainability, the core of its meaning is normative. When the concept of...
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Technological Progress in the Life Sciences
The new gene-editing tool, CRISPR-Cas9, been described as “revolutionary” This paper takes up the question of what sense, if any, might this be true...
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Islamic Perspectives on CRISPR/Cas9-Mediated Human Germline Gene Editing: A Preliminary Discussion
The recent development of CRISPR/Cas9 technology has rekindled the ethical debate concerning human germline modification that has begun decades ago....
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Manipulated Evolution and Artificial Life
Since the 1970s, laboratory methods have been developed in molecular biology that allow for the manipulation of the DNA sequences of genes or the...
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Specificity as a Guide for the Safe Use of Human Germline Gene Editing—A Response to Sarkar’s Cut and Paste Genetics
For human germline gene editing to be a viable technique for preventing disease, it must meet a baseline level of safety. This commentary unpacks...
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Ethical Issues Concerning Genetically Modified Animals for the Study of Human Diseases
The development of genetically modified model organisms for the study of human diseases may be beneficial in the research of causes and possible...
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Introduction: International Public Health: Morality, Politics, Poverty, War, Disease
This introduction sets out a general model of how to think about public health—starting with the conditions that should initiate the threats to the...
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Bioethical Decision-Making About Somatic Cell Genome Editing: Sickle-Cell Disease as a Case Study
Somatic cell genome editing (SCGE) now allows exquisitely precise and targeted non-heritable changes to be made to human DNA. While SCGE has many...
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The Debate on Biotechnology and Genetic Therapy
This chapter discusses some of the ethical dilemmas around genetic engineering. First, it provides a brief review of the historical and scientific...
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When is it Safe to Edit the Human Germline?
In the fall of 2018 Jiankui He shocked the international community with the following announcement: two female babies, “Lulu” and “Nana,” whose...
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Good Reasons to Avoid Germline Intervention: A Response to Sahotra Sarkar
This essay takes issue with the statement by the biologist and philosopher Sahotra Sarkar in his recent book Cut-and-Paste Genetics: A CRISPR...
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Emerging Reproductive Technologies: Regulating Into the Void
This chapter offers an overview of the American legal landscape surrounding assisted reproductive technologies (ART). The three basic sources of law...