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Identification and Evaluation of Free Radical Scavenging Activity of Quinolizidine Alkaloids Isolated from Various Parts of Anagyris foetida Plant
Anagyris foetida is a genus of legumes belonging to the Fabaceae family, considered as a good source of medications to treat various ailments. In...
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Phytochemical Screening, Free-Radical Scavenging Activity, in vitro Alpha-Amylase Inhibitory Activity, and in vivo Hypoglycemic Activity Studies of Several Crude Drug Formulations Based on Selected Medicinal Plants of Nepal
Diabetes mellitus (DM) is a chronic metabolic disorder leading toward elevation of the blood glucose level due to insulin insufficiency (Type I) or...
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Anti-inflammatory, Radical-Scavenging, and Chelating Activities of Nor-Triterpenes from Galphimia Species
Anti-inflammatory and radical-scavenging activities of the methanolic extract from the leaves of Galphimia spp. collected in Morelos, Mexico, and...
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Synthesis, In Silico Analysis, Antibacterial, Radical Scavenging and Antidiabetic Activities of Certain Bis-Azetidinones and Bis-Thiazolidinones
A panel of 1,1-(phenylene)bis[3-chloro-4-(substituted phenyl)azetidin-2-ones] ( 4a-m ) and 3,3′-(1,4-phenylene)bis[2-(substituted...
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The Relationship of Free Radical Scavenging and Total Phenolic and Flavonoid Contents of Garcinia lasoar PAM
The radical scavenging assays of 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and 2,2′-azino-bis-3-ethylbenzothiazoline-6-sulphonic (ABTS) acid for...
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Phenolic Compounds and Radical Scavenging Activity of Senna tora (L.) Roxb. Herbs Collected from Various Geographical Locations of India
Senna tora (L.) Roxb. syn Cassia tora L., commonly known as sickle pod, is widely distributed in tropical Asian countries. Various parts of the plant...
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In Silico Studies and DNA Cleavage, Antioxidant, Acetylcholinesterase, and Butyrylcholinesterase Activity Evaluation of Bis-Histamine Schiff Bases and Bis-Spinaceamine Substituted Derivatives
In this work, a series of seven bis-histamine Schiff bases ( H1–H4 ) and bis-spinaceamine substituted derivatives ( SPH1 , SPH2 , and SPH4 ) were...
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Pyrazoline and Hydrazone Derivatives as Potent Membrane Stabilizer and Antioxidant Compounds
Membrane-stabilizing and antioxidant activities of twenty six pyrazoline and hydrazone derivatives were investigated. Antioxidant activity of these...
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In Vitro Antioxidant Activity of Asteriscus Graveolens (Forsk.) and Its Protective Effect on Doxorubicin-Induced Hepatotoxicity and Testicular Oxidative Damage in Rats
Asteriscus graveolens (Asteraceae) is a medicinal herb, used in Algeria to treat diabetes, hypertension, pain, fever, inflammation and...
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Free Radical Scavenging and Cytotoxic Properties of Acylated and Non-Acylated Kaempferol Glycosides from Stenochlaena Palustris: a Perspective on Their Structure – Activity Relationships
Flavonoid glycosides that are present in acylated form have good prospect to be developed into therapeutic agents due to their improved biological...
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IN-VITRO Assessment of Anti-Cholinesterase, Anti-Lipase, Antioxidant Activities and Photoprotective Effect of Algerian Fagonia bruguieri DC Extracts
This is the first study aimed to investigate the anti-cholinesterase (anti-Alzheimer), anti-lipase, antioxidant and photoprotective effects of...
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Water Soluble Curcuminoids: Encapsulation into Cyclodextrins and In-vitro Antioxidant Properties
A water-soluble curcuminoid powder was developed using cyclodextrins and quantified individual curcuminoids using high-performance liquid...
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Protection of the hematopoietic system against radiation-induced damage: drugs, mechanisms, and developments
Sometimes, people can be exposed to moderate or high doses of radiation accidentally or through the environment. Radiation can cause great harm to...
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Molecular and Therapeutic Insights of Alpha-Lipoic Acid as a Potential Molecule for Disease Prevention
Alpha-lipoic acid is an organic, sulfate-based compound produced by plants, humans, and animals. As a potent antioxidant and a natural dithiol...
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Antibacterial, Antioxidant and DNA Cleavage Activity Evaluation of Substituted Phenylureido Sulfaguanidine and Sulfamethazine Derivatives
A series of six N -carbamimidoyl-4-(3-substituted phenylureido) benzenesulfonamides ( SG1-SG6 ) and six N-(4,6-dimethylpyrimidin-2-yl)-4-(3-substituted...
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Evaluation of Biological Activities and Enzyme Inhibitory Potential of 7,8-Dihydroxy-3-(4-methylphenyl) Coumarin
In this study, antioxidant, antibacterial, cytotoxic, and antioxidant enzyme inhibitory properties of the 7,8-dihydroxy-3-(4-methylphenyl) coumarin...
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Investigation and Characterization of Novel Biologically Active Secondary Metabolites from Melissa officinalis L.
Plants have very important chemical components, known as secondary metabolites, for the pharmaceutical industry, as well as for the chemical,...
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New benzimidazole-aldehyde hybrids as neuroprotectors with hypochlorite and superoxide radical-scavenging activity
BackgroundMany neurodegenerative disorders include oxidative stress-mediated pathology. Melatonin and its metabolites act as endogenous reactive...
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Synthesis, Characterization, and In Vitro Antimicrobial and Antioxidant Study of the Pentacoordinated Organotin(IV) Complexes Based on Acid Hydrazide Schiff Base Ligands
In the present study, the equimolar reactions of dialkyltin (IV) dichlorides with Schiff base ligands have been processed, and from these reactions a...
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Design and Synthesis of Novel Pyrazolo[3,4-d]Pyrimidines: In Vitro Cytotoxic Evaluation and Free Radical Scavenging Activity Studies
With evident biological importance, a new series of pyrazolo[3,4- d ]pyrimidines 3a,3b and 4a,4b were synthesized via the formation of pyrazol-3-one 2a ...
