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Validation of a Method of Measuring Mean Molecular Weight of Dextrans by Diffusion-Ordered Spectroscopy
Amethod for measuring the mean molecular weight of dextrans by diffusion-ordered NMR spectroscopy was developed and validated. This method allows...
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Study of the Adhesive Characteristics of Mucoadhesive Polymer Systems by Rotational Viscometry
None of the methods currently proposed for studying various adhesion characteristics of polymers and approved for use in dosage form formulations is...
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Utilizing Solid-State NMR Spectroscopy to Assess Properties of Lyophilized Formulations
Solid-state nuclear magnetic resonance (NMR) spectroscopy (SSNMR) is a powerful analytical technique that can be utilized to study lyophilized...
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Formulation Design for Freeze-Drying: Case Studies of Stabilization of Proteins
Formulation design is an integral part of drug product development for parenterally applied dosage forms. In particular for freeze-dried...
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Pharmacokinetic Study of Oxidized Dextrans
Methods of obtaining biotinylated oxidized dextran (BTOD) and procedures for pharmacokinetic studies of BTOD and biotinylated dextran (BTD) are...
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Single enzyme nanoparticle, an effective tool for enzyme replacement therapy
The term “single enzyme nanoparticle” (SEN) refers to a chemically or biologically engineered single enzyme molecule. SENs are distinguished from...
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Comparative Efficacies of Doxorubicin Complexes with Dextran Phosphate and Dextran Sulfate for Intracavity Chemotherapy of Zajdela Ascitic Hepatoma in Rats
The efficacies of doxorubicin (Dox) complexes with carbohydrate polymers dextran phosphate (DP) and dextran sulfate (DS) in rats with grafted Zajdela...
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Water-Soluble Polysaccharides from Leaves of Abelmoschus esculentus: Purification, Characterization, and Antioxidant Activity
Two water-soluble polysaccharides were obtained from the leaves of Abelmoschus esculentus using aqueous extraction and purification with DEAE-52 and...
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Structural Characterization and Antioxidant Activity of a Novel Alkaline-Soluble Polysaccharide from Patrinia villosa
A novel alkaline-soluble polysaccharide (PVPS-3), obtained from Patrinia villosa by 9.0% NaOH extraction, was fractionated by anion-exchange and gel...
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The isolation and the characterization of two polysaccharides from the branch bark of mulberry (Morus alba L.)
Two water-soluble polysaccharides termed MBBP-1 and MBBP-2 were isolated from the branches of the mulberry tree ( Morus alba L.) using hot water...
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Change of Polysaccharide Molecular-Weight Distribution and Fraction Homogeneity After Periodate Oxidation
The effect of periodate oxidation on the molecular weight and fraction homogeneity of dextran dialdehydes and carboxymethylcellulose dialdehydes was...
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Quality Control of Polysaccharide Molecular-Weight Distributions Using Exclusion Chromatography with a Multi-Angle Laser Light Scattering Detector
Quality control of drugs based on hydroxyethyl starch (HES) was shown to be possible using an absolute analytical method for the molecular-weight...
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Gel chromatographic and toxicological studies of the mechanochemical transformations of water-soluble polysaccharides
Changes in the molecular weight characteristics of polysaccharide macromolecules - arabinogalactan, hydroxyethyl starch 200/0.5, Fibregum, and...
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Improved production, purification and bioactivity of a polysaccharide from submerged cultured Ganoderma lucidum
Polysaccharides from Ganoderma lucidum showed multiple biological activities, such as immuno-modulating, antitumor, antioxidant, and hepatoprotective...
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Physicochemical and electron-microscopic study of carrageenans, sulfated polysaccharides from red algae of the families Tichocarpaceae and Gigartinaceae
The physicochemical properties and morphology of κ, κ/β, κ/ι, and λ-carrageenans from red algae of the families Gigartinaceae and Tichocarpaceae were...
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Nanotechnology in Cancer
Cancer nanotechnology, defined as nanotechnology applicable for diagnosis, prognosis, and therapy of cancer, offers exciting possibilities but also...
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Method for determining the number of aldehydes in dextran polyaldehyde using 2,4-dinitrophenylhydrazine
A method for determining the number of aldehydes in dextran polyaldehyde (DPA) was proposed. The method was based on the production of the...
