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Concepts and Strategies in the Design of Formulations for Freeze Drying
In order to enhance the storage stability of water labile molecules the common practice is to employ lyophilization (freeze drying) process to create...
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Validation of the specialized competency framework for pharmacists in hospital settings (SCF–PHS): a cross-sectional study
ObjectivesThis study aimed to validate the content of the specialized competency frameworks for pharmacists working in hospital settings (hospital...
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Central nervous system disorders after use of dolutegravir: evidence from preclinical and clinical studies
The evaluation of dolutegravir based on available preclinical and clinical studies reveals a risk of central nervous system (CNS) disorders...
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Cannabinoids in the treatment of glioblastoma
Glioblastoma (GBM) is the most prevalent primary malignant tumor of the nervous system. While the treatment of other neoplasms is increasingly more...
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Biodegradable Long-Acting Injectables: Platform Technology and Industrial Challenges
Long-acting injectables have been used to benefit patients with chronic diseases. So far, several biodegradable long-acting platform technologies...
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Enhancement of S(+)-zaltoprofen oral bioavailability using nanostructured lipid carrier system
Zaltoprofen is a nonsteroidal anti-inflammatory drug with poor oral bioavailability. S(+)-zaltoprofen (SZPF)-loaded nanostructured lipid carriers...
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Recent Formulation Advances of Mangiferin
Nutraceuticals have recently gained interest owing to their valuable contribution in the treatment of several diseases, with high safety margin and...
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Pharmacokinetic-Pharmacodynamic Characterization of a Topical Photochemotherapy Using Brosimum gaudichaudii in C56BL/6 Mice
Photochemotherapy or ultraviolet radiating treatment is widely used in the treatment of vitiligo via oral dosages that often resulted in high...
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Application of 3D Whole-Brain Texture Analysis and the Feature Selection Method Based on within-Class Scatter in the Classification and Diagnosis of Alzheimer’s Disease
BackgroundPatients with mild cognitive impairment (MCI) are a high-risk group for Alzheimer’s disease (AD). Thus, a reliable prediction of the...
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Design and Process Considerations in Spray Freeze Drying
Dynamic spray freeze drying combines spray freezing and rotary freeze drying to generate homogeneous, free-flowing lyophilized beads as a bulk...
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Dermal
Preparations for cutaneous (or dermal) application may be used for local treatment as well as for transdermal administration with a systemic effect....
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QUALITY REQUIREMENTS FOR HERBAL DRUGS; ANALYTICAL METHODS
In the broadest sense, all plants that are used for healing purposes, based on either traditional use or scientific data, are referred to as...
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Therapeutic Proteins and Advanced Therapy Medicinal Products
This chapter is divided in two parts: Therapeutic proteins and Advanced Therapy Medicinal Products (ATMPs)....
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Antiviral Properties of Baicalin: a Concise Review
Baicalin is one of the bioactive flavonoid glycosides isolated from the dried root of Scutellaria baicalensis Georgi, Lamiaceae, with antiviral...
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Liquid Crystals: Characteristics, Types of Phases and Applications in Drug Delivery
The present review article relates to some theoretical aspects of liquid crystals, particularly types and phases of liquid crystals. In recent years...
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Rectal and Vaginal
This chapter discusses dosage forms for rectal and vaginal use. The main focus is on suppositories and on small-scale preparation methods. The...
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Raw Materials
Raw materials for pharmaceutical preparations are either active substances (or active pharmaceutical ingredients (APIs)) or excipients. The choice of...
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Validation of a Method of Measuring Mean Molecular Weight of Dextrans by Diffusion-Ordered Spectroscopy
Amethod for measuring the mean molecular weight of dextrans by diffusion-ordered NMR spectroscopy was developed and validated. This method allows...
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Cytotoxic Activity and Kinetic Release Study of Lovastatin-Loaded Ph-Sensitive Polymersomes
Triblock poly(ε-caprolactone) – poly(ethylene glycol) – poly(ε-caprolactone) (PCL-PEG-PCL) copolymers were synthesized and used to prepare...
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Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Emerging Lipid Based Drug Delivery Systems
In the past decade, research in the area of nanodrug delivery has reached a new height with the advent of lipid based nanodrug delivery systems....