Search
Search Results
-
Cucurbitane Triterpene Glycosides from the Roots of Wilbrandia hibiscoides
In this study, we isolated and identified cucurbitane triterpene glycosides of Wilbrandia hibiscoides Silva Manso contributing to the phytochemistry...
-
Diuretic Effect in Rats of Betulinic Acid, a Pentacyclic Triterpene from Citharexylum myrianthum
The diuretic effect of betulinic acid obtained from the hexane fraction of branches of Citharexylum myrianthum Cham., Verbenaceae, was evaluated in...
-
Characterization of Triterpene Saponins from Gypsophila arrostii by Electrospray Ionization Ion Trap Multiple-Stage Mass Spectrometry
Saponins are natural surfactant compounds whose aqueous solutions can form stable foam and micellar solutions. Gypsophila arrostii Guss.,...
-
Secondary Metabolites of Oplopanax elatus: Possibilities for Standardization of a Multiphytoadaptogen for Preventive Oncology
An herbal formulation of a multiphytoadaptogen (MPA) developed at the N. N. Blokhin Cancer Center and containing phytocomponents from Oplopanax elatus ...
-
Synthesis of O-Vinyl Ethers of Pentacyclic Triterpene Alcohols and Lupane-Type Oximes
Vinylation by acetylene of lupane-type pentacyclic triterpene C-28- and C-3 β -alcohols and C-20-oximes in superbase solutions synthesized the...
-
Creation of Modified Forms of Amiodarone with Glycyrrhizic Acid and Its Monoammonium Salt and Study of Their Cytotoxicity on Hela Cells
The aim of this work is to create new modified dosage forms of amiodarone with triterpene glycosides in various stoichiometric ratios and to study...
-
Boswellic Acid Nanoparticles: Promising Strategies for Increasing Therapeutic Effects
Boswellic acids, the main active compound found in the oleo-gum resin of Boswellia serrata Roxb., Burseraceae, have been used in traditional and...
-
Annonaceae Terpenoids as Potential Leishmanicidal Agents
Leishmaniasis is a neglected tropical disease caused by protozoa of the genus Leishmania . Current drug treatments for leishmaniasis are outdated and...
-
A New Triterpene and a New Phloroglucinol Derivative from the Aerial Parts of Pogostemon auricularius
A new triterpene, pogostem ( 1 ), and a new phloroglucinol derivative, pogostemon D ( 2 ), were isolated from the aerial parts of Pogostemon auricularius...
-
Brazilian Medicinal Plants with Antiamyloidogenic Activity
Amyloid fibrillation is a process involved in a large set of pathologies, including diabetes and Alzheimer’s. Although Brazil has a large...
-
Metabolomic Profiling and Cytotoxic Activity of Launaea nudicaulis: Molecular Docking with Topoisomerases
Launaea nudicaulis (L.) Hook. f., Asteraceae, is a wild plant growing in Egypt, used traditionally for treatment of many diseases. LC-HRMS analysis...
-
Cytotoxic Activity of A-Modified Licorice Triterpenoid Derivatives
The cytotoxic activity of a number of A-modified derivatives of glycyrrhetic acid (GLA) and 11-deoxo- and 18,19-dehydro-GLA against conditionally...
-
Betulinic Acid Modulates Redox Imbalance and Dysregulated Metabolisms, While Ameliorating Purinergic and Cholinergic Activities in Iron-Induced Neurotoxicity
The neuroprotective properties of betulinic acid were investigated in oxidative-mediated neurotoxicity induced with Fe 2+ in isolated rats’ brains....
-
Anti-Methicillin-Resistant S. aureus Activity of Fruiting Body and Mycelial Culture Extracts of Xylaria longipes Nitschke (Ascomycota)
Resistance to penicillin by Staphylococcus aureus gave rise to methicillin-resistant S. aureus (MRSA) and the emergence of vancomycin-resistant S....
-
Synthesis and Transformation of Triterpenoids with a β-Ketonitrile Fragment in Five-Membered Ring A
Triterpenoids with a β -ketonitrile group in five-membered ring A were synthesized via intramolecular oxonitrile cyclization of C-3 methyl esters of...
-
Friedelin and 3β-Friedelinol: Pharmacological Activities
The interest in herbal medicine as a source of drug leads is being reinforced, especially for tackling challenging therapeutic areas such as...
-
DISCUSSION OF HERBAL DRUGS BASED ON THE BIOGENETIC CLASSIFICATION OF THEIR MAIN ACTIVE COMPONENTS
Honey is prepared by honey-bees (Apis mellifera) from the nectar and honeydew of flowers. After chemical conversion by the gastric juices in the...
-
BIOSYNTHESIS OF PLANT SUBSTANCES; BIOGENETIC RELATIONSHIPS
The bioactive substances in medicinal plants will be discussed on the basis of their chemical structure, or more precisely, of a...
-
Triterpene Saponins from Branches of Pinus massoniana
Two triterpene saponins, including a new one named ursolic acid 3-O-β-D-glucopyranosyl...
-
Ginsenoside Rg5 as an anticancer drug: a comprehensive review on mechanisms, structure–activity relationship, and prospects for clinical advancement
Cancer remains one of the leading causes of death in the world. Despite the considerable success of conventional treatment strategies, the incidence...
