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1. Calycosin Alleviates Lupus Nephritis by Activating the Nrf2/HO-1 Signaling Pathway

   Lupus nephritis is a serious condition, for which treatments are limited; hence, there is a need for new cure approaches. The aim of this study was...

   Yang Yu, Peng Sun in Revista Brasileira de Farmacognosia

   Article Open access 14 August 2023
   

2. The role of glucagon-like peptide-1/GLP-1R and autophagy in diabetic cardiovascular disease

   Diabetes leads to a significantly accelerated incidence of various related macrovascular complications, including peripheral vascular disease and...

   Zi Guo in Pharmacological Reports

   Article 19 June 2024
   

3. Paeoniflorin increases the survival of Pseudomonas aeruginosa infected Caenorhabditis elegans at the immunosuppression stage by activating PMK-1, BAR-1, and EGL-1 signals

   Paeoniflorin is the major active compound of total glycoside of paeony in Paeonia lactiflora Pall. Although several aspects of beneficial effects of...

   Le Zhang, Yuxing Wang, Dayong Wang in Archives of Pharmacal Research

   Article 01 July 2023
   

4. Synthesis and Adenosine RA₁/A_2A Receptor Affinity of Selected Aurones and 2-Benzylidene-1-Indanones

   In the search to discover new adenosine A ₁ /A _2A receptor ligands, ten aurones (2-benzylidenebenzofuran-3(2H)-ones) and 2-benzylidene-1-indanones were...

   Helena D. Janse van Rensburg, Gisella Terre’Blanche, Lesetja J. Legoabe in Pharmaceutical Chemistry Journal

   Article 01 August 2023
   

5. Synthesis and Antidepressant Activity of Thietane-Containing 4-(2-oxo-2-phenylethyl)-1H-1,2,4-triazol-4-ium Bromides

   Thietane-containing 4-(2-oxo-2-phenylethyl)-1 H -1,2,4-triazol-4-ium bromides were synthesized by quaternization of thietanyltriazoles with phenacyl...

   F. A. Khaliullin, E. E. Klen, ... A. V. Samorodov in Pharmaceutical Chemistry Journal

   Article 20 March 2023
   

6. Synthesis and Antiaggregant and Anticoagulant Activity of New 1-(4-Alkyloxybenzyl)-1H-Azoles and 1-(Adamantyl-1)-2-[4-(1H-Azol-1-Ylmethyl)-Phenoxy]Ethanones

   The development and optimization of synthetic methods for alkyl esters of 4-[(1 H -azol-1-yl)methyl]phenols enabled the expansion of organic synthesis...

   K. G. Gurevich, A. L. Urakov, ... A. V. Samorodov in Pharmaceutical Chemistry Journal

   Article 20 November 2021
   

7. Safety of Intravenous Pantoprazole Sodium in Pediatric Patients Aged 1 Month to < 1 Year: A Real-World Retrospective Cohort Study

   Objective

   To estimate the incidence rates (IR) of prespecified outcomes of interest in pediatric patients (1 month to < 1 year) treated with...

   Sampada Gandhi, Benjamin Taylor, ... Kevin Wolter in Therapeutic Innovation & Regulatory Science

   Article 27 October 2023
   

8. Synthesis and Antidepressant Activity of 5-Amine-Substituted 3-Bromo-1-(1,1-Dioxothietan-3-yl)-4-Nitro-1H-Pyrazoles

   5-Amino-substituted 3-bromo-1-(1,1-dioxothietan-3-yl)-4-nitro-1 H -pyrazoles were synthesized via the reactions of...

   E. E. Klen, I. L. Nikitina, ... V. N. Pavlov in Pharmaceutical Chemistry Journal

   Article 01 November 2023
   

9. A 1-year analysis of adverse events following COVID-19 vaccination in Lebanon: a retrospective study

   Background

   Since the deployment of Coronavirus Disease 2019 (COVID-19) vaccines, skepticism about the safety, incidence, and severity of Adverse...

   Abeer Zeitoun, Souheil Hallit, ... Rita Karam in Journal of Pharmaceutical Policy and Practice

   Article Open access 21 February 2023

10. Synthesis and Analgesic Activity of New Analogs of 1-[1-phenylcyclohexyl]piperidine with Modified Structures in its Tricyclic System

    1-[1-Phenylcyclohexyl]piperidine (Phencyclidine, PCP ) is a tricyclic compound with an aromatic ring that can create a negative charge area, a...

    Maryam Shokrollahi, Seyed Ali Sobhanian, ... Mohsen Pooladi in Pharmaceutical Chemistry Journal

    Article 01 August 2023
    

11. Identification of mitogen-activated protein kinase phosphatase-1 (MKP-1) protein partners using tandem affinity purification and mass spectrometry

    Background

    According to the World Health Organization Report, depressive disorders affect about 10% of the population. The molecular mechanism of the...

    Ewelina Fic, Agata Cieślik, ... Marta Dziedzicka-Wasylewska in Pharmacological Reports

    Article Open access 24 March 2023
    

12. Formulating GML-1 Tablets Using the Harrington Desirability Function

    Features of using the generalized Harrington desirability function for the selection of a binder and lubricant for GML-1 ( N -benzyl- N -methyl-1-phenylpyrrolo[1,2-...

    D. I. Gavrilov, E. V. Blynskaya, ... K. V. Alekseev in Pharmaceutical Chemistry Journal

    Article 01 April 2024
    

13. Correction to: Common Chinese Materia Medica – Volume 1

    Common Chinese Materia Medica Volume 1

    Huagu Ye in Common Chinese Materia Medica

    Chapter 2022
    

14. Tapinarof cream 1% in plaque psoriasis: a profile of its use

    Tapinarof (VTAMA ^® ) cream 1%, a topical, non-steroidal, aryl hydrocarbon receptor agonist, presents a valuable addition to the therapy options for...

    Matt Shirley in Drugs & Therapy Perspectives

    Article 27 July 2023

15. Ursodeoxycholic Acid Enhances the Antibacterial Activity of Colistin by Inhibiting MCR-1

    Colistin is recognized as the “last line of defense” for the treatment of carbapenemase-producing “super-resistant” bacteria. However, the treatment...

    **nyu Yao, Yang Shu, ... Tianqi Fang in Revista Brasileira de Farmacognosia

    Article 07 February 2024
    

16. Synthesis and Biological Activity of 5-alkoxy- and 5-amino-substituted 3-bromo-4-nitro-1-(thietan-3-yl)-1H-pyrazoles

    5-Alkoxy- and 5-amino-substituted 3-bromo-4-nitro-1-(thietan-3-yl)-1 H -pyrazoles were synthesized by reactions of...

    F. A. Khaliullin, E. E. Klen, ... T. N. Abzalilov in Pharmaceutical Chemistry Journal

    Article 27 May 2022
    

17. Diacerein counteracts acetaminophen-induced hepatotoxicity in mice via targeting NLRP3/caspase-1/IL-1β and IL-4/MCP-1 signaling pathways

    The current study aims at repurposing the anti-arthritic drug diacerein (DCN) for the treatment of acetaminophen hepatotoxicity and investigating the...

    Mahmoud Elshal, Marwa E. Abdelmageed in Archives of Pharmacal Research

    Article Open access 04 March 2022
    

18. Novel object recognition test as an alternative approach to assessing the pharmacological profile of sigma-1 receptor ligands

    Background

    Although the terms “agonist” and “antagonist” have been used to classify sigma-1 receptor (σ ₁ R) ligands, an unambiguous definition of the...

    Katarzyna Szczepańska, Andrzej J. Bojarski, ... Natalia Malikowska-Racia in Pharmacological Reports

    Article Open access 12 August 2023
    

19. Liquiritin Relieves LPS-Induced Endometritis Through Activating Keap1/Nrf2/HO-1 Signaling Pathway

    Liquiritin is a flavonoid extracted from Glycyrrhiza glabra L., Fabaceae, which possesses anti-inflammatory and antioxidant activities. However, the...

    Sheng **, Chunyan Mo, ... **g Chen in Revista Brasileira de Farmacognosia

    Article 07 February 2023
    

20. Anti HSV-1 Activity of Cistus laurifolius and Development of Antiviral Herbal Lip Balm

    Cistus laurifolius L., Cistaceae, has long been used for traditional treatments against various skin diseases in Turkey. The study was designed to...

    Nurullah Okumuş, Sevim Feyza Erdoğmuş, ... Ümmühan Ünlü in Revista Brasileira de Farmacognosia

    Article 31 January 2024