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“I feel drug resistance testing allowed us to make an informed decision”: qualitative insights on the role of HIV drug resistance mutation testing among children and pregnant women living with HIV in western Kenya
BackgroundPregnant women and children living with HIV in Kenya achieve viral suppression (VS) at lower rates than other adults. While many factors...
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When and How Should Resistance Testing Be Performed to Improve H. pylori Eradication?
Purpose of ReviewTreatment of Helicobacter pylori ( H. pylori ) has historically been managed with empiric regimens comprising proton pump inhibitors...
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Antifungal Resistance, Susceptibility Testing and Treatment of Recalcitrant Dermatophytosis Caused by Trichophyton indotineae: A North American Perspective on Management
There is an ongoing epidemic of chronic, relapsing dermatophytoses caused by Trichophyton indotineae that are unresponsive to one or multiple...
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RNA-based antibiotic susceptibility testing of tmexCD-toprJ-mediated tigecycline resistance in Klebsiella pneumoniae
The emergence and prevalence of plasmid-encoded RND-type efflux pump TMexCD-TOprJ severely compromise tigecycline treatment, which is recognized as...
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Analysis of Platelet Function Testing in Children Receiving Aspirin for Antiplatelet Effects
Aspirin (ASA) remains the most common antiplatelet agent used in children. VerifyNow Aspirin Test® (VN) assesses platelet response to ASA, with...
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Next-generation microbiological testing in intraabdominal infections with PCR technology
PurposeIntraabdominal infections (IAI) are increasing worldwide and are a major contributor to morbidity and mortality. Among IAI, the number of...
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Effectiveness of preoperative thoracic epidural testing strategies: a retrospective comparison of three commonly used testing methods
PurposeThoracic epidural analgesia (TEA) is a well stablished technique for pain management in major thoracic and abdominal surgeries; however, it...
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Characterization and implications of intracoronary hemodynamic assessment during coronary spasm provocation testing
BackgroundCurrent diagnostic criteria for coronary spasm are based on patient’s symptoms, ECG shifts and epicardial vasoconstriction during...
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Tuberoplasty reduces resistance force in dynamic shoulder abduction for irreparable rotator cuff tears: a cadaveric biomechanical study
BackgroundArthroscopic tuberoplasty is an optional technique for managing irreparable rotator cuff tears. However, there is a lack of studies...
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Role of Immunological Testing in Infertility
Purpose of ReviewUnexplained infertility, recurrent pregnancy loss, and recurrent implantation failure are challenging clinical scenarios, both for...
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Insulin resistance syndrome presenting with diabetic ketoacidosis — a rare presentation
We report an adolescent male who presented with diabetic ketoacidosis (DKA). He was diagnosed to have type 1 diabetes mellitus at the age of 12 years...
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Trend of distribution and antimicrobial resistance in uropathogens in China from the CHINET antimicrobial resistance surveillance program, a 7-year retrospective study
Urinary tract infections (UTIs) are common urological diseases that easily relapse and have led to an increasing economic and health burdens. The...
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Analysis of ART effects and drug resistance in adult HIV/AIDS patients in Meigu County, Liangshan Prefecture, China
Background objectiveThis study aimed to understand the basic situation of adults with human immunodeficiency virus (HIV) receiving antiretroviral...
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Testing for deficient mismatch repair and microsatellite instability
Testing to detect mismatch repair deficiency (dMMR) and high-grade microsatellite instability (MSI-H) has become an integral part of the routine...
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Antimicrobial Resistance in Cirrhosis
Purpose of ReviewAntimicrobial resistance (AMR) is recognized as a critical global public health threat. This paper provides a comprehensive overview...
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Organisation of testing services, structural barriers and facilitators of routine HIV self-testing during sexually transmitted infection consultations: a qualitative study of patients and providers in Abidjan, Côte d’Ivoire
BackgroundConsultations for sexually transmitted infection (STI) provide an opportunity to offer HIV testing to both patients and their...
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Antimicrobial resistance profiles of bacterial isolates from clinical specimens referred to Ethiopian Public Health Institute: analysis of 5-year data
BackgroundAntimicrobial resistance is one of the common global public health problems. The emergence of antimicrobial resistance is multifactorial,...
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Changing antimicrobial resistance profile of Enterobacter spp. isolates in hospitals across China: a seven-year analysis from the CHINET antimicrobial resistance surveillance program (2015–2021)
Antimicrobial resistance poses a global threat to human health. Analyzing monitoring data on antimicrobial resistance can assist clinicians in making...
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Tenofovir diphosphate in dried blood spots and HIV-1 resistance in South Africa
BackgroundSuboptimal antiretroviral (ART) adherence can lead to virologic failure with consequent HIV-1 resistance. Tenofovir diphosphate (TFV-DP) in...
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Simulation device for shoulder reductions: overview of prototy**, testing, and design instructions
BackgroundShoulder dislocations are common occurrences, yet there are few simulation devices to train medical personnel on how to reduce these...