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Immunoreactivity of HOXB13 in Neuroendocrine Neoplasms Is a Sensitive and Specific Marker of Rectal Well-Differentiated Neuroendocrine Tumors
HoxB13 is a transcription factor involved in defining of posterior endodermal derivatives, including prostate and rectum. While it is used as a...
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Molecular Classification of Gastrointestinal and Pancreatic Neuroendocrine Neoplasms: Are We Ready for That?
In the last two decades, the increasing availability of technologies for molecular analyses has allowed an insight in the genomic alterations of...
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Imaging of neuroendocrine neoplasms of the male GU tract
Male genitourinary neuroendocrine neoplasms (GU-NENs) are rare, without any definite imaging characteristics. The WHO classified neuroendocrine...
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Adult NTRK-rearranged spindle cell neoplasms of the viscera: with an emphasis on rare locations and heterologous elements
NTRK -rearranged mesenchymal neoplasms mostly affect the soft tissues of pediatric patients. Given the responsiveness to selective NTRK inhibitors, it...
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Handling and pathology reporting guidelines for bladder epithelial neoplasms – recommendations from the Brazilian Society of Pathology / Brazilian Society of Urology / Brazilian Society of Clinical Oncology
The Brazilian Society of Pathology Guidelines Project aims to provide recommendations for clinicians and pathologists based on the best available...
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Re-evaluating tumors of purported specialized prostatic stromal origin reveals molecular heterogeneity, including non-recurring gene fusions characteristic of uterine and soft tissue sarcoma subtypes
Tumors of purported specialized prostatic stromal origin comprise prostatic stromal sarcomas (PSS) and stromal tumors of uncertain malignant...
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Phox2B is a sensitive and reliable marker of paraganglioma—Phox2B immunohistochemistry in diagnosis of neuroendocrine neoplasms
Phox2B is a transcription factor responsible for chromaffin cell phenotype. Although it is used routinely for diagnosis of neuroblastoma, previous...
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Radiologic-pathologic correlation of prostatic cancer extracapsular extension (ECE)
AbstractRecent advancements on nerve-sparing robotic prostatectomy allow fewer side effects such as urinary incontinence and sexual dysfunction. To...
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Prostatic tissue: an unexpected finding in a mature ovarian teratoma
PurposeProstatic tissue in an ovarian teratoma is an unusual finding, whose initiation in a 46, XX karyotype tissue is yet to be clarified. We...
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Hemorrhagic cystitis in allogeneic stem cell transplantation: a role for age and prostatic hyperplasia
PurposeHemorrhagic cystitis (HC) is a frequent complication of allogeneic hematopoietic stem-cell transplantation (HSCT). HC worsens transplant...
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PET/CT and PET/MRI in neuroendocrine neoplasms
Advanced molecular imaging has come to play an integral role in the management of gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NENs)....
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Progress of immunotherapies in gestational trophoblastic neoplasms
BackgroundDifferent from other malignant gynecologic tumors, gestational trophoblastic neoplasms (GTNs) exhibit an exceptionally high cure rate...
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Challenges in High-grade Neuroendocrine Neoplasms and Mixed Neuroendocrine/Non-neuroendocrine Neoplasms
The growth in knowledge of the pathogenesis, molecular background, and immunohistochemical profile of neuroendocrine neoplasms (NENs) has led not...
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Rare paraneoplastic syndrome of prostatic cancer: limbic encephalitis: a case report
IntroductionLimbic encephalitis is an autoimmune neurologic disorder, often of paraneoplastic origin, that seldom complicates prostatic tumors. The...
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Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Overview of the 2022 WHO Classification of Head and Neck Neuroendocrine Neoplasms
This review article provides a brief overview of the new WHO classification by adopting a question–answer model to highlight the spectrum of head and...
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Well-differentiated neuroendocrine tumor of the urinary bladder expressing GATA 3
Neuroendocrine neoplasms of the urinary bladder are uncommon tumors represented by small-cell neuroendocrine carcinoma and by fewer cases of...
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Prostein expression in human tumors: a tissue microarray study on 19,202 tumors from 152 different Tumor entities
BackgroundProstein (P501S), also termed solute carrier family 45 member 3 (SLC45A3) is an androgen regulated protein which is preferentially...
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Classification of neuroendocrine neoplasms: lights and shadows
Neuroendocrine neoplasms (NENs) are a heterogeneous group of neoplastic proliferations showing different morphological features, immunophenotype,...
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New PET Radiotracers for the Imaging of Neuroendocrine Neoplasms
Neuroendocrine neoplasms (NEN) are a heterogeneous group of tumours derived from cells of neuroendocrine origin and can potentially arise everywhere...
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Identifying the deceiver: the non-neoplastic mimickers of genital system neoplasms
Tumors of the genital system are common and imaging is of crucial importance for their detection and diagnosis. Several non-neoplastic diseases may...
