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Predictive value of maternal serum placental growth factor levels for discordant fetal growth in twins: a retrospective cohort study
BackgroundAccurate prenatal recognition of discordant fetal growth in twins is critical for deciding suitable management strategies. We explored the...
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Expression of placental growth factor, neuropilin-1, and neuropilin-2 in primary pterygium tissue
PurposeThe aim of this study was to evaluate the expression of placental growth factor (PLGF), neuropilin-1 (NP-1), and neuropilin-2 (NP-2) molecules...
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Placental microRNAs relate to early childhood growth trajectories
BackgroundPoor placental function is a common cause of intrauterine growth restriction, which in turn is associated with increased risks of adverse...
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Placental Growth Factor in First Trimester of Pregnancy for Prediction of Maternal and Perinatal Adverse Outcomes
Purpose of the studyPlacental growth factor (PLGF) is an angiogenic factor in pregnancy. To find out correlation of plasma levels of placental growth...
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Placental growth factor level is correlated with intrapartum fetal heart rate findings
ObjectiveHere, we tested the correlation between maternal placental growth factor (PlGF) and fetal heart rate (FHR) monitoring findings.
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Association of angiogenic factors (placental growth factor and soluble FMS-like tyrosine kinase-1) in preeclamptic women of African ancestry comorbid with HIV infection
BackgroundPreeclampsia is a significant cause of maternal and fetal morbidity and mortality, particularly in low- and middle-income countries like...
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Depletion of placental brain-derived neurotrophic factor (BDNF) is attributed to premature ovarian insufficiency (POI) in mice offspring
IntroductionPremature ovarian insufficiency (POI) is one of the causes of female infertility. Unexplained POI is increasingly affecting women in...
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Evaluation of placental growth potential and placental bed perfusion by 3D ultrasound for early second-trimester prediction of preeclampsia
PurposeThis study aimed to investigate whether placental parameters measured by three-dimensional ultrasound are associated with preeclampsia (PE)...
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Reduced T2*-weighted placental MRI predicts foetal growth restriction in women with chronic rheumatic disease—a Danish explorative study
ObjectivesWomen with chronic rheumatic disease (CRD) are at greater risk of foetal growth restriction than their healthy peers. T2*-weighted magnetic...
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Long-Term Predictors of Gestational Hypertension: Placental Growth Factor, Pregnancy-Associated Plasma Protein-A and Free Beta-Hcg Versus Mean Arterial Pressure and Uterine Artery Doppler Versus a Combination of Both: A Comparative Study
BackgroundAccording to WHO, hypertensive disease is the leading cause of direct maternal mortality accounting for 10–25% in develo** countries...
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Role of EZH2-mediated H3K27me3 in placental ADAM12-S expression: implications for fetoplacental growth
BackgroundEnhancer of zeste homolog 2 (EZH2)-mediated histone 3 lysine 27 trimethylation (H3K27me3) is a transcription silencing mark, which is...
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The associations of gestational weight gain and midpregnancy lipid levels with placental size and placental-to-birth weight ratio: findings from a chinese birth cohort study
BackgroundThe placenta serves as the sole maternal organ responsible for transmitting nutrients to the fetus, playing a crucial role in supporting...
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Hypothesis: human trophectoderm biopsy downregulates the expression of the placental growth factor gene
Preeclampsia (PE) and intrauterine growth retardation (IUGR) are the results of defective placentation associated with the downregulation of...
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Isolated oligohydramnios in previous pregnancy is a risk factor for a placental related disorder in subsequent delivery
BackgroundWe aimed to assess the association between isolated oligohydramnios in previous pregnancy and the incidence of placental related...
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Maternal PUFAs, Placental Epigenetics, and Their Relevance to Fetal Growth and Brain Development
Dietary polyunsaturated fatty acids (PUFAs), especially omega-3 (n-3) and n-6 long-chain (LC) PUFAs, are indispensable for the fetus’ brain supplied...
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Thyroid hormone transport and metabolism are disturbed in the placental villi of miscarriage
BackgroundIt has been long known that thyroid hormone regulates placental villi development, which is associated with the occurrence of miscarriage....
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Identification of key genes in pathogenesis of placental insufficiency intrauterine growth restriction
BackgroundIntrauterine growth restriction (IUGR) is defined as a fetus that fails to achieve its genetically determined growth potential. The exact...
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Placental growth fActor Repeat sampling for Reduction of adverse perinatal Outcomes in women with suspecTed pre-eclampsia: study protocol for a randomised controlled trial (PARROT-2)
BackgroundPre-eclampsia is a complex pregnancy disorder, characterised by new or worsening hypertension associated with multi-organ dysfunction....
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Neuroprotective effects of maternal melatonin administration in early-onset placental insufficiency and fetal growth restriction
BackgroundEarly-onset fetal growth restriction (FGR) is associated with adverse outcomes. We hypothesised that maternal melatonin administration will...
