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The impact of sericin on inflammation, oxidative stress, and lipid metabolism in female rats with experimental knee osteoarthritis
ObjectiveThis study investigated the effects of sericin on inflammation, oxidative stress, and lipid metabolism in female rats with experimental knee...
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circFAM193B interaction with PRMT6 regulates AML leukemia stem cells chemoresistance through altering the oxidative metabolism and lipid peroxidation
Most forms of chemotherapy for acute myeloid leukemia (AML) are often ineffective in eliminating leukemic stem cells (LSCs), as their underlying...
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The impact of different levels of wheat diets on hepatic oxidative stress, immune response, and lipid metabolism in Tibetan sheep (Ovis aries)
BackgroundCompared with corn, wheat contains higher crude protein, amino acids concentration. However, wheat contains a mass of anti-nutritional...
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Effects of aerobic exercise training in oxidative metabolism and mitochondrial biogenesis markers on prefrontal cortex in obese mice
BackgroundTo evaluate the effects of 8 weeks of Aerobic Physical Training (AET) on the mitochondrial biogenesis and oxidative balance in the...
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Energy metabolism: a new target for gastric cancer treatment
Gastric cancer is the fifth most common malignancy worldwide having the fourth highest mortality rate. Energy metabolism is key and closely linked to...
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Possible Role of Cellular Polyamine Metabolism in Neuronal Apoptosis
Recent studies have shown that cellular levels of polyamines (PAs) are significantly altered in neurodegenerative diseases. Evidence from in vivo ...
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RNA modifications in cellular metabolism: implications for metabolism-targeted therapy and immunotherapy
Cellular metabolism is an intricate network satisfying bioenergetic and biosynthesis requirements of cells. Relevant studies have been constantly...
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Perinatal stress exposure induced oxidative stress, metabolism disorder, and reduced GLUT-2 in adult offspring of rats
PurposeGrowing evidence has demonstrated that adversity in early life, especially in the prenatal and postnatal period, may change the programming of...
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Metabolism, metabolites, and macrophages in cancer
Tumour-associated macrophages (TAMs) are crucial components of the tumour microenvironment and play a significant role in tumour development and drug...
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Novel Insights into Osteoclast Energy Metabolism
Purpose of ReviewOsteoclasts are crucial for the dynamic remodeling of bone as they resorb old and damaged bone, making space for new bone. Metabolic...
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Sex Differences in Energy Metabolism: A Female-Oriented Discussion
The purpose of this review is to delineate aspects of energy metabolism at rest and during exercise that may be subject to sex differences and the...
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Pharmacological Effects of Botanical Drugs on Myocardial Metabolism in Chronic Heart Failure
Although there have been significant advances in the treatment of heart failure in recent years, chronic heart failure remains a leading cause of...
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Pyruvate Dehydrogenase Kinase 1 inhibition mediated oxidative phosphorylation enhancement in cartilage promotes osteoarthritis progression
Osteoarthritis (OA) is a common disease characterized by cartilage degradation. Growing evidence showed that glucose metabolism impacts joint...
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Comprehensive analysis of biological landscape of oxidative stress-related genes in diabetic erectile dysfunction
Oxidative stress plays a pivotal role in the pathogenesis of diabetic erectile dysfunction, while specific mechanisms have not been illuminated. The...
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Multi-omics analysis of a case of congenital microtia reveals aldob and oxidative stress associated with microtia etiology
BackgroundMicrotia is reported to be one of the most common congenital craniofacial malformations. Due to the complex etiology and the ethical...
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The attenuated hepatic clearance of propionate increases cardiac oxidative stress in propionic acidemia
Propionic acidemia (PA), arising from PCCA or PCCB variants, manifests as life-threatening cardiomyopathy and arrhythmias, with unclear...
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Effects of antipsychotic drugs on energy metabolism
Schizophrenia (SCZ) is a complex neuropsychiatric disorder associated with altered bioenergetic pathways and mitochondrial dysfunction. Antipsychotic...
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Altered Energy Metabolism, Mitochondrial Dysfunction, and Redox Imbalance Influencing Reproductive Performance in Granulosa Cells and Oocyte During Aging
Female fertility decreases during aging. The development of effective therapeutic strategies to address the age-related decline in oocyte quality and...
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Ovarian aging: energy metabolism of oocytes
In women who are getting older, the quantity and quality of their follicles or oocytes and decline. This is characterized by decreased ovarian...
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Signatures of metabolic diseases on spermatogenesis and testicular metabolism
Diets leading to caloric overload are linked to metabolic disorders and reproductive function impairment. Metabolic and hormonal abnormalities stand...