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Showing 1-20 of 7,655 results
  1. Concomitant use of monoamine oxidase inhibitor and tyrosine in parenteral nutrition

    Monoamine oxidase inhibitors (MAOIs) prevent the breakdown of tyramine in the body, and can cause a sudden increase in blood pressure with...

    Tina Bharani, Kris M. Mogensen, ... Malcolm K. Robinson in European Journal of Clinical Nutrition
    Article 07 December 2023
  2. Targeting monoamine oxidase A: a strategy for inhibiting tumor growth with both immune checkpoint inhibitors and immune modulators

    Monoamine oxidase A (MAOA) is a membrane-bound mitochondrial enzyme present in almost all vertebrate tissues that catalyzes the degradation of...

    Yifan Ma, Hanmu Chen, ... Changhong Shi in Cancer Immunology, Immunotherapy
    Article Open access 13 February 2024
  3. Toxic interactions between dopamine, α-synuclein, monoamine oxidase, and genes in mitochondria of Parkinson’s disease

    Parkinson’s disease is characterized by its distinct pathological features; loss of dopamine neurons in the substantia nigra pars compacta and...

    Makoto Naoi, Wakako Maruyama, ... Peter Riederer in Journal of Neural Transmission
    Article 09 January 2024
  4. Impact of genetic variants within serotonin turnover enzymes on human cerebral monoamine oxidase A in vivo

    Variants within the monoamine oxidase A (MAO-A, MAOA ) and tryptophan hydroxylase 2 (TPH2 ) genes, the main enzymes in cerebral serotonin (5-HT)...

    Marie Spies, Matej Murgaš, ... Rupert Lanzenberger in Translational Psychiatry
    Article Open access 15 June 2023
  5. High monoamine oxidase a expression predicts poor prognosis for prostate cancer patients

    Background

    Monoamine oxidase A (MAOA) is a mitochondrial enzyme that is involved in prostate tumorigenesis and cancer metastasis. The predictive power...

    Lingxiao Chen, Wei **ong, ... Wei He in BMC Urology
    Article Open access 04 July 2023
  6. Characterization of monoamine oxidase-B (MAO-B) as a biomarker of reactive astrogliosis in Alzheimer’s disease and related dementias

    Reactive astrogliosis accompanies the two neuropathological hallmarks of Alzheimer’s disease (AD)—Aβ plaques and neurofibrillary tangles—and...

    Methasit Jaisa-aad, Clara Muñoz-Castro, ... Alberto Serrano-Pozo in Acta Neuropathologica
    Article Open access 03 April 2024
  7. Monoamine oxidase A-dependent ROS formation modulates human cardiomyocyte differentiation through AKT and WNT activation

    During embryonic development, cardiomyocytes undergo differentiation and maturation, processes that are tightly regulated by tissue-specific...

    Moises Di Sante, Salvatore Antonucci, ... Nina Kaludercic in Basic Research in Cardiology
    Article Open access 20 January 2023
  8. Prescription Pattern of Monoamine Oxidase B Inhibitors Combined with Levodopa: A Retrospective Observational Analysis of Italian Healthcare Administrative Databases

    Background

    Parkinson’s disease is still incurable, and several factors are considered when defining pharmacological therapy.

    Objective ...
    Giulia Ronconi, Silvia Calabria, ... Nello Martini in Drugs - Real World Outcomes
    Article Open access 13 June 2022
  9. Monoamine oxidase binding not expected to significantly affect [18F]flortaucipir PET interpretation

    Purpose

    [ 18 F]-labeled positron emission tomography (PET) radioligands permit in vivo assessment of Alzheimer’s disease biomarkers, including...

    Justin P. Wright, Jason R. Goodman, ... Kelly A. Conway in European Journal of Nuclear Medicine and Molecular Imaging
    Article Open access 21 May 2022
  10. Age-related increase of monoamine oxidase B in amyloid-negative cognitively unimpaired elderly subjects

    Objective

    Monoamine oxidase B (MAO-B) is highly abundant in reactive astrocytes and upregulated in neuroinflammatory processes. However, the...

    Keita Sakurai, Takashi Nihashi, ... MULNIAD study group in Annals of Nuclear Medicine
    Article 04 July 2022
  11. Effects of monotherapy with a monoamine oxidase B inhibitor on motor symptoms in Parkinson’s disease are dependent on frontal function

    Background

    Monotherapy with monoamine oxidase B (MAO-B) inhibitors enhances the level of endogenous dopamine in treatment for Parkinson’s disease (PD)...

    Hidetomo Murakami, Motohiro Okumura, ... Yasuyuki Iguchi in Neurological Sciences
    Article 15 November 2022
  12. Monoamine oxidase A and organic cation transporter 3 coordinate intracellular β1AR signaling to calibrate cardiac contractile function

    We have recently identified a pool of intracellular β 1 adrenergic receptors (β 1 ARs) at the sarcoplasmic reticulum (SR) crucial for cardiac function....

    Ying Wang, Meimi Zhao, ... Yang K. **ang in Basic Research in Cardiology
    Article Open access 17 July 2022
  13. Site-activated multi target iron chelators with acetylcholinesterase (AChE) and monoamine oxidase (MAO) inhibitory activities for Alzheimer’s disease therapy

    The first class of site-activated chelators with dual inhibition of acetyl-cholinesterase (AChE) and monoamine oxidase (MAO), rationally designed for...

    Moussa B. H. Youdim in Journal of Neural Transmission
    Article 21 February 2022
  14. Monoamine Oxidase Inhibitors (MAOIs) in Psychiatric Practice: How to Use them Safely and Effectively

    Monoamine oxidase inhibitors (MAOIs) were among the first licensed pharmacological treatments for patients with depression but over time have fallen...

    Samuel R. Chamberlain, David S. Baldwin in CNS Drugs
    Article 09 July 2021
  15. Associations of age, sex, sexual abuse, and genotype with monoamine oxidase a gene methylation

    Epigenome-wide studies report higher methylation among women than men with decreasing levels with age. Little is known about associations of sex and...

    David Checknita, Jari Tiihonen, ... Kent W. Nilsson in Journal of Neural Transmission
    Article Open access 23 August 2021
  16. The trace amine theory of spontaneous hypertension as induced by classic monoamine oxidase inhibitors

    The classic monoamine oxidase inhibitors (MAOIs) tranylcypromine (TCP) and phenelzine (PLZ) are powerful antidepressants that come with an equally...

    Vincent Van den Eynde in Journal of Neural Transmission
    Article 09 August 2021
  17. Recent advances on the role of monoamine oxidases in cardiac pathophysiology

    Numerous physiological and pathological roles have been attributed to the formation of mitochondrial reactive oxygen species (ROS). However, the...

    Nina Kaludercic, Ruth Jepchirchir Arusei, Fabio Di Lisa in Basic Research in Cardiology
    Article Open access 04 October 2023
  18. Association between monoamine oxidase A promoter polymorphism and the risk of sudden infant death syndrome: a meta-analysis

    Introduction

    The etiology of sudden infant death syndrome (SIDS) remains an unsolved problem. The aim of this meta-analysis is to investigate the...

    Qiaoxia Zhou, Daoyin Gong, ... Feijun Huang in International Journal of Legal Medicine
    Article Open access 01 February 2021
  19. Common network effect-patterns after monoamine reuptake inhibition in dissociated hippocampus cultures

    The pharmacological treatment of major depressive disorder with currently available antidepressant drugs is still unsatisfying as response to...

    Julia Trepl, Marc Dahlmanns, ... Jana Katharina Dahlmanns in Journal of Neural Transmission
    Article Open access 24 February 2022
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