Search
Search Results
-
Mechanism of Qili Qiangxin Capsule for Heart Failure Based on miR133a-Endoplasmic Reticulum Stress
ObjectiveTo investigate the pharmacological mechanism of Qili Qiangxin Capsule (QLQX) improvement of heart failure (HF) based on miR133a-endoplasmic...
-
The role of miR1 and miR133a in new-onset atrial fibrillation after acute myocardial infarction
BackgroundThe development of new-onset atrial fibrillation (NOAF) after acute myocardial infarction (AMI) is a clinical complication that requires a...
-
Identification of a circulating microRNAs biomarker panel for non-invasive diagnosis of coronary artery disease: case–control study
BackgroundCirculating microRNAs (miRNAs) are considered a hot spot of research that can be employed for monitoring and/or diagnostic purposes in...
-
Epigenetic analyses in forensic medicine: future and challenges
The possibility of using epigenetics in forensic investigation has gradually risen over the last few years. Epigenetic changes with their dynamic...
-
Metabolic, structural and biochemical changes in diabetes and the development of heart failure
Diabetes contributes to the development of heart failure through various metabolic, structural and biochemical changes. The presence of diabetes...
-
A small RNA, microRNA as a potential biomolecular marker to estimate post mortem interval in forensic science: a systematic review
BackgroundPost-mortem interval (PMI) is the cornerstone of the forensic field to investigate. The examination technique by seeing the changes in the...
-
miRNA expression in PCOS: unveiling a paradigm shift toward biomarker discovery
Polycystic ovary syndrome (PCOS) is a complex endocrine disorder that affects a substantial percentage of women, estimated at around 9–21%. This...
-
Downregulation of lncRNA Miat contributes to the protective effect of electroacupuncture against myocardial fibrosis
BackgroundMyocardial fibrosis changes the structure of myocardium, leads to cardiac dysfunction and induces arrhythmia and cardiac ischemia,...
-
MicroRNAs as the critical regulators of protein kinases in prostate and bladder cancers
BackgroundBladder cancer (BCa) and prostate cancer (PCa) are frequent urothelial and genital malignancies with a high ratio of morbidity and...
-
The Role of Adipose Tissue-derived Exosomes in Chronic Metabolic Disorders
Excessive fat deposition in obese subjects promotes the occurrence of metabolic diseases, such as type 2 diabetes mellitus (T2DM), cardiovascular...
-
Isolated downregulation of HCN2 in ventricles of rats with streptozotocin-induced diabetic cardiomyopathy
BackgroundIn spite of disrupted repolarization of diabetic heart, some studies report less tendency of diabetic heart to develop ventricular...
-
Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity
Disease progression and therapeutic resistance of prostate cancer (PC) are linked to multiple molecular events that promote survival and plasticity....
-
A systematic review of miRNAs as biomarkers in osteoporosis disease
BackgroundOsteoporosis is often considered to be a disease of the elderly, which is characterized by two characteristics: low bone mineral density...
-
Air pollution and children’s health—a review of adverse effects associated with prenatal exposure from fine to ultrafine particulate matter
BackgroundParticulate matter (PM), a major component of ambient air pollution, accounts for a substantial burden of diseases and fatality worldwide....
-
Hyperglycemic memory in diabetic cardiomyopathy
Cardiovascular diseases account for approximately 80% of deaths among individuals with diabetes mellitus, with diabetic cardiomyopathy as the major...
-
Top Five Stories of the Cellular Landscape and Therapies of Atherosclerosis: Current Knowledge and Future Perspectives
Atherosclerosis (AS) is characterized by impairment and apoptosis of endothelial cells, continuous systemic and focal inflammation and dysfunction of...
-
Serum microRNA 143 as a potential biomarker for the diagnosis of hepatitis C virus-related hepatocellular carcinoma
BackgroundHepatocellular carcinoma (HCC) is the fifth most frequently diagnosed cancer worldwide. Early recognition of the onset of HCC would help to...
-
The Exosome-Derived Biomarker in Atherosclerosis and Its Clinical Application
Exosomes are now accepted as potential biomarkers in cardiovascular disease development, especially in atherosclerosis. Atherosclerosis is a leading...
-
Evaluating the potential of housekee** genes, rRNAs, snRNAs, microRNAs and circRNAs as reference genes for the estimation of PMI
The precise estimation of postmortem interval (PMI) is a critical step in death investigation of forensic cases. Detecting the degradation of RNA in...
