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Plasma miRNAs improve the prediction of coronary atherosclerosis in patients with rheumatoid arthritis
ObjectiveMicroRNAs (miRNAs) regulate gene expression and are disease biomarkers. Rheumatoid arthritis (RA) patients have accelerated atherosclerosis...
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Circulating miRNAs drive personalized medicine based on subgroup classification in myasthenia gravis patients
Myasthenia gravis (MG) is a classic autoimmune neuromuscular disease with strong clinical heterogeneity. The concept of subgroup classification was...
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Baseline levels of miR-223-3p correlate with the effectiveness of electroconvulsive therapy in patients with major depression
There is a strong medical need to develop suitable biomarkers to improve the diagnosis and treatment of depression, particularly in predicting...
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Altered expression of apoptosis-related, circulating cell-free miRNAs in children with familial Mediterranean fever: a cross-sectional study
ObjectivesFamilial Mediterranean Fever (FMF) is the most common hereditary autoinflammatory disorder characterized by recurrent fever and serositis...
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Differences between psoriatic arthritis and psoriasis in multi-omics
We aim to systemically review the genomics, transcriptomics, epigenetics, proteomics, metabonomics and microbiota of psoriatic arthritis and...
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The role of Extracellular Genomic Materials (EGMs) in psychiatric disorders
Extracellular Genomic Materials (EGMs) are the nucleic acids secreted or released from all types of cells by endogenous or exogenous stimuli through...
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MicroRNAs: circulating biomarkers for the early detection of imperceptible cancers via biosensor and machine-learning advances
This review explores the topic of microRNAs (miRNAs) for improved early detection of imperceptible cancers, with potential to advance precision...
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MicroRNA as a potential biomarker for systemic lupus erythematosus: pathogenesis and targeted therapy
Systemic lupus erythematosus (SLE) is an autoimmune disease associated with hyperactive innate and adaptive immune systems that cause dermatological,...
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Exosome is a Fancy Mobile Sower of Ferroptosis
Exosomes, nano-sized small extracellular vesicles, have been shown to serve as mediators between intercellular communications by transferring...
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MicroRNA expression profiling of RAS-mutant thyroid tumors with follicular architecture: microRNA signatures to discriminate benign from malignant lesions
PurposeRAS mutations represent common driver alterations in thyroid cancer. They can be found in benign, low-risk and malignant thyroid tumors with...
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The Effects of MicroRNAs in the Development of Heart Failure
Purpose of ReviewHeart failure is a severe clinical syndrome with complex and unclarified mechanisms, and it poses a serious threat to human health....
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Diagnostic and prognostic potential of long non-coding RNA NORAD in patients with acute deep vein thrombosis and its role in endothelial cell function
BackgroundDeep venous thrombosis (DVT) is the common clinical cardiovascular disease, and easily develops into post-thrombotic syndrome (PTS). The...
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MicroRNAs secreted by human preimplantation embryos and IVF outcome
ObjectiveTo generate an effective embryo prediction model and identify a non-invasive evaluation method by analyzing microRNAs (miRNAs) in embryo...
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MicroRNAs serve as prediction and treatment-response biomarkers of attention-deficit/hyperactivity disorder and promote the differentiation of neuronal cells by repressing the apoptosis pathway
Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental disorder. This study aimed to examine whether miRNA...
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MiR-30 promotes fatty acid beta-oxidation and endothelial cell dysfunction and is a circulating biomarker of coronary microvascular dysfunction in pre-clinical models of diabetes
BackgroundType 2 diabetes (T2D) is associated with coronary microvascular dysfunction, which is thought to contribute to compromised diastolic...
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Blood miRNA levels associated with ADHD traits in children across six European birth cohorts
BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a prevalent and highly heritable neurodevelopmental disorder of major societal concern....
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Comprehensive Analysis of microRNA Expression During the Progression of Colorectal Tumors
BackgroundNo effective early diagnostic biomarkers are available for colorectal cancer (CRC). Therefore, we sought to identify new biomarkers that...
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MiR-214-3p Prevents the Development of Perioperative Neurocognitive Disorders in Elderly Rats
ObjectiveThis study aimed to identify microRNAs (miRNAs) involved in the development of perioperative neurocognitive disorders (PND).
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Deleted in lymphocytic leukemia 2 (DLEU2): a possible biomarker that holds promise for future diagnosis and treatment of cancer
The mechanism of deleted in lymphocytic leukemia 2 (DLEU2)-long non-coding RNA in tumors has become a major point of interest in recent research...