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Bone mesenchymal stem cell-derived extracellular vesicles containing NORAD promote osteosarcoma by miR-30c-5p
Osteosarcoma is a bone tumor that often affects children, adolescents and young people. Non-coding RNA activated by DNA damage (NORAD) can promote...
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Downregulation of lncRNA SNHG16 inhibits vascular smooth muscle cell proliferation and migration in cerebral atherosclerosis by targeting the miR-30c-5p/SDC2 axis
Atherosclerosis (AS) is the basic lesion underlying the occurrence and development of cerebrovascular diseases. Abnormal proliferation of vascular...
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Association of Trophectoderm mRNAs and MicroRNAs with Chromosomal Aneuploidy of Embryo
MicroRNAs (miRNAs) and mRNAs can serve as indicators of the chromosomal state of an embryo, with different profiles observed in euploid and aneuploid...
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MiR-34c-5p Inhibition Affects Bax/Bcl2 Expression and Reverses Bortezomib Resistance in Multiple Myeloma Cells
Develo** resistance to anticancer drugs complicates the clinical treatment of multiple myeloma patients. Previous studies revealed a link between...
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The role of microRNA-30c in targeting interleukin 6, as an inflammatory cytokine, in the mesenchymal stem cell: a therapeutic approach in colorectal cancer
IntroductionColorectal cancer (CRC) is the third most prevalent cancer and the second significant cause of cancer-associated death worldwide. The...
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CircRNA/miRNA/mRNA axis participates in the progression of partial bladder outlet obstruction
BackgroundMore and more evidence showed that circRNA/miRNA/mRNA axis played a vital role in the pathogenesis of some diseases. However, the role of...
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Circulating microRNA alternations in primary hyperuricemia and gout
ObjectivesMicroRNAs (miRNAs) are short single-stranded RNAs that play a role in the post-transcriptional regulation of gene expression. Their...
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Screening for genes, miRNAs and transcription factors of adipogenic differentiation and dedifferentiation of mesenchymal stem cells
BackgroundThe purpose of present study was to reveal the molecular mechanisms responsible for both adipogenic differentiation and dedifferentiation...
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Diabetes induces dysregulation of microRNAs associated with survival, proliferation and self-renewal in cardiac progenitor cells
Aims/hypothesisDiabetes mellitus causes a progressive loss of functional efficacy in stem cells, including cardiac progenitor cells (CPCs). The...
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MiR-30c/PGC-1β protects against diabetic cardiomyopathy via PPARα
BackgroundMetabolic abnormalities have been implicated as a causal event in diabetic cardiomyopathy (DCM). However, the mechanisms underlying cardiac...
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Embryo morphokinetic score is associated with biomarkers of developmental competence and implantation
PurposeTo study embryo morphokinetics in relation to release in spent media of molecules with possible roles in development and implantation...
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Implications of GCLC in prognosis and immunity of lung adenocarcinoma and multi-omics regulation mechanisms
BackgroundFerroptosis is an iron-dependent type of regulated cell death, and has been implicated in lung adenocarcinoma (LUAD). Evidence has proved...
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Hypoxia-mediated down-regulation of miRNAs’ biogenesis promotes tumor immune escape in bladder cancer
BackgroundThe study examines the function of hypoxia-mediated down-regulation of microRNAs (miRNAs) (mir-30c, mir-135a, and mir-27a) in the process...
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MicroRNAs and Circular RNAs in Lipoprotein Metabolism
Purpose of ReviewNon-coding RNAs (ncRNAs) including microRNAs (miRNAs) and circular RNAs (circRNAs) are pivotal regulators of mRNA and protein...
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Rno-microRNA-30c-5p promotes myocardial ischemia reperfusion injury in rats through activating NF-κB pathway and targeting SIRT1
BackgroundThis study aimed to investigate the regulatory effect of rno-microRNA-30c-5p (rno-miR-30c-5p) on myocardial ischemia reperfusion (IR)...
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Plasma miRNAs improve the prediction of coronary atherosclerosis in patients with rheumatoid arthritis
ObjectiveMicroRNAs (miRNAs) regulate gene expression and are disease biomarkers. Rheumatoid arthritis (RA) patients have accelerated atherosclerosis...
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RETRACTED ARTICLE: MicroRNA-30c-regulated HDAC9 mediates chemoresistance of breast cancer
PurposeAlthough histone deacetylase (HDAC) inhibitors have been shown to effectively induce the inhibition of proliferation and migration in breast...
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Therapeutic angiogenesis with exosomal microRNAs: an effectual approach for the treatment of myocardial ischemia
Therapeutic angiogenesis presents a potential approach for treating ischemic heart diseases especially in patients who are not appropriate candidates...
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MicroRNA in dried blood spots from patients with Aagenaes syndrome and evaluation of pre-analytical and analytical factors
BackgroundCirculatory miRNAs are promising biomarkers. The feasibility of using miRNA from dried blood spots (DBS) was investigated using newborn...
