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Characterization of Hyaluronan Localization in the Develo** Mammary Gland and Mammary Tumors
The extracellular matrix (ECM) is biochemically and biomechanically important for the structure and function of the mammary gland, which undergoes...
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Using Organoids to Tap Mammary Gland Diversity for Novel Insight
This article offers a comprehensive perspective on the transformative role of organoid technology on mammary gland biology research across a diverse...
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MicroRNA miR-223 modulates NLRP3 and Keap1, mitigating lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells and murine mammary glands
Bovine mastitis, the most prevalent and costly disease in dairy cows worldwide, decreases milk quality and quantity, and increases cow culling....
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Renal pelvic plasmacytoid subtype urothelial carcinoma accompanied with solitary mammary metastasis
A 72-year-old female was referred to our institution for further evaluation of right renal tumor detected during work-up for macroscopic hematuria in...
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Longitudinal analysis of bovine mammary gland development
Many studies on bovine mammary glands focus on one stage of development. Often missing in those studies are repeated measures of development from the...
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Transcriptomic Analysis of Pubertal and Adult Virgin Mouse Mammary Epithelial and Stromal Cell Populations
Conflicting data exist as to how mammary epithelial cell proliferation changes during the reproductive cycle. To study the effect of endogenous...
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Methods for investigating STAT3 regulation of lysosomal function in mammary epithelial cells
The transcription factor STAT3 is activated by multiple cytokines and other extrinsic factors. It plays a key role in immune and inflammatory...
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Preoperative visualization of mammary artery for breast reduction surgery based on computed tomography angiography
BackgroundMacromastia, characterized by an increase in breast size, poses challenges such as elevated body burden and chest oppression, potentially...
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Fourteenth Annual ENBDC Workshop: Methods in Mammary Gland Biology and Breast Cancer
The fourteenth annual workshop of the European Network for Breast Development and Cancer (ENBDC) on Methods in Mammary Gland Biology and Breast Cancer ...
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Toward Characterizing Lymphatic Vasculature in the Mammary Gland During Normal Development and Tumor-Associated Remodeling
Lymphatic vasculature has been shown to promote metastatic spread of breast cancer. Lymphatic vasculature, which is made up of larger collecting...
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Single-Cell Transcription Map** of Murine and Human Mammary Organoids Responses to Female Hormones
During female adolescence and pregnancy, rising levels of hormones result in a cyclic source of signals that control the development of mammary...
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Deciphering Stromal Changes between Metastatic and Non-metastatic Canine Mammary Carcinomas
Cancer-associated stroma (CAS) is widely recognized to influence development and progression of epithelial tumours including breast cancer. Canine...
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Hormonal regulation of mammary gland development and lactation
Lactation is critical to infant short-term and long-term health and protects mothers from breast cancer, ovarian cancer and type 2 diabetes mellitus....
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Usability of serum hedgehog signalling proteins as biomarkers in canine mammary carcinomas
BackgroundThe hedgehog signalling pathway has been implicated in tumourigenesis and progression of many tumour types. This pathway has recently...
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Distinct Requirements for Adaptor Proteins NCK1 and NCK2 in Mammary Gland Development
The adaptor proteins NCK1 and NCK2 are well-established signalling nodes that regulate diverse biological processes including cell proliferation and...
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Soluble CD14 produced by bovine mammary epithelial cells modulates their response to full length LPS
Bovine mastitis remains a major disease in cattle world-wide. In the mammary gland, mammary epithelial cells (MEC) are sentinels equipped with...
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Upregulation of SLUG expression in canine mammary gland tumors and its prognostic significance
BackgroundSLUG (also known as snai2), which is a transcription factor in epithelial–mesenchymal transition (EMT), plays an important role in...
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Spatial Engineering of Mammary Epithelial Cell Cultures with 3D Bioprinting Reveals Growth Control by Branch Point Proximity
The three-dimensional (3D) structure of the ductal epithelium and the surrounding extracellular matrix (ECM) are integral aspects of the breast...
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Reproducible isolation of bovine mammary macrophages for analysis of host pathogen interactions
BackgroundMacrophages residing in milk are vital during intramammary infections. This study sought to develop a method enabling the investigation of...
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Mesenchymal stromal cells modulate infection and inflammation in the uterus and mammary gland
The use of mesenchymal stromal cells (MSCs) is emerging as an efficacious and safe treatment for many infectious and non-infectious inflammatory...
