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Mechanical and Enzymatic Digestion of Autologous Fat Grafting (A-FG): Fat Volume Maintenance and AD-SVFs Amount in Comparison
BackgroundCurrently, several techniques for autologous fat graft (A-FG) preparation aimed at obtaining purified tissue exist. Both mechanical...
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Effect of accelerated high-fluence riboflavin and rose bengal-mediated corneal cross-linking on resistance to enzymatic digestion
PurposeThis study evaluated the effect of high-fluence accelerated corneal cross-linking on the resistance to enzymatic digestion, assessing two...
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Effects of different grains on bacterial diversity and enzyme activity associated with digestion of starch in the foal stomach
BackgroundCompared with the stomach of ruminant cattle, the stomach of horse is small and mainly for chemical digestion, but the microorganisms in...
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Efficient in vitro oxaliplatin delivery with functionalized single-walled carbon nanotube for enhanced colon cancer treatment
BackgroundSite-specific transport of medicinal products to malignant cells and tissues is an intriguing area since it has an ability to safeguard...
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An in vitro investigation into the impact of corneal rinsing on riboflavin/UVA corneal cross-linking
BackgroundCorneal cross-linking (CXL) using riboflavin and ultraviolet-A light (UVA) is a treatment used to prevent progression of keratoconus. This...
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In vitro efficacy of intralesional Collagenase Clostridium Histolyticum for the treatment of calcified Peyronie’s disease plaques
Peyronie’s disease (PD) is defined by penile plaque formation and curvature causing sexual dysfunction. The only FDA-approved intralesional treatment...
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Effect of beta-glucan supplementation on cystic fibrosis colonic microbiota: an in vitro study
BackgroundChildren with cystic fibrosis (CF) present with gut dysbiosis, and current evidence impedes robust recommendations on the use of...
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Florfenicol sustained-release granules: an in vitro-in vivo correlation study in pigs
The objective of this study was to synthesize and characterize pharmaceutical characteristics of florfenicol sustained-release granules (FSRGs) in...
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Amniotic Fluid Proteomics Analysis and In Vitro Validation to Identify Potential Biomarkers of Preterm Birth
This study aimed to investigate the regulation of amniotic fibroblast (AFC) function by vitamin K–dependent protein Z (PROZ) during preterm birth...
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Quantification of Cardiomyocyte Contraction In Vitro and Drug Screening by MyocytoBeats
Cardiomyocyte contractility is the crucial feature of heart function. Quantifying cardiomyocyte contraction in vitro is essential for disease...
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Successful isolation of viable stem cells from cryopreserved microfragmented human adipose tissue from patients with knee osteoarthritis – a comparative study of isolation by tissue explant culture and enzymatic digestion
PurposeTo investigate if viable stem cells could be isolated and expanded from cryopreserved microfragmented adipose tissue (AT) harvested from...
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In vitro T cell responses to PD-1 blockade are reduced by IFN-α but do not predict therapy response in melanoma patients
PD-1 blockade therapy has revolutionized melanoma treatment, but still not all patients benefit and pre-treatment identification of those patients is...
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Medium supplementation can influence the human ovarian cells in vitro
BackgroundCells are an essential part of the triple principles of tissue engineering and a crucial component of the engineered ovary as they can...
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Selected coffee (Coffea arabica L.) extracts inhibit intestinal α-glucosidases activities in-vitro and postprandial hyperglycemia in SD Rats
One of the therapeutic approaches for decreasing postprandial hyperglycemia is to retard absorption of glucose by the inhibition of carbohydrate...
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In-vitro generation of follicle-like structures from human germ cell-like cells derived from theca stem cell combined with ovarian somatic cells
BackgroundThe objective of this study was to induce the differentiation of human theca stem cells (hTSCs) into germ cell-like cells (hGCLCs) and...
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Kaempferol prevents aseptic loosening via enhance the Wnt/β-catenin signaling pathway in vitro and in vivo
Kaempferol has demonstrated notable positive effects on the osteogenic differentiation of mesenchymal stem cells (MSC) and osteoblasts. A substantial...
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Effect of digestion on stability of palivizumab IgG1 in the infant gastrointestinal tract
BackgroundPotentially, orally administered antibodies specific to enteric pathogens could be administered to infants to prevent diarrheal infections,...
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Carrot pomace powder: a promising source of polyphenols and prebiotics for improving gut health
PurposeThis study aimed to evaluate the properties of carrot pomace, including its nutritional composition, physiochemical attributes, change in...
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Antimicrobial peptide Mastoparan X has good activity against Escherichia coli in vitro and alleviates its pathogenicity in mice
BackgroundEscherichia coli is a facultative anaerobic bacterium that normally resides in the gastrointestinal tract of humans and animals but can...