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Oral health status and oral habits of children and adolescents with hemophilia: a report from the children’s hemophilia comprehensive care center of China
In recent years, the diagnosis and treatment of hemophilic children in China has significantly improved. However, oral health conditions, which...
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A rare twist: COVID-19 infection masquerading as IgA vasculitis in a hemophilia a patient
Hemophilia A and B are one of the most common hereditary bleeding disorders. Patients are predisposed to bleeding spontaneously or after minor trauma...
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Skeletal complications in patients with hemophilia: a single-center experience
BackgroundArthropathy is a common complication in patients with hemophilia. We examined the prevalence of this skeletal complication in patients with...
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Perioperative Management of Hemophilia Patients
Purpose of ReviewHemophilia is a rare, typically inherited, condition where a specific clotting factor is reduced or even near absent. Patients with...
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Hemophilia A and factor V deficiency in a girl with Turner syndrome: a case report
BackgroundHemophilia is an X-linked, recessive inherited disease caused by a defect or deficiency of one of the coagulation factors (VIII or IX). It...
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Clinical Analysis and Mental Health Survey of Hemophilia Carriers: a Cross-sectional Study
ObjectiveHemophilia carriers (HCs), who are heterozygous for mutations in the clotting factor VIII/clotting factor IX gene ( F8 or F9 ), may have a...
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Pain: a neglected symptom in hemophilia
Repetitive bleeding attacks may cause joint pain and arthropathy in patients with hemophilia (PWH). Despite being a common symptom, pain is not a...
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Bleeding management: rFVIIIFc in hemophilia A and liver transplantation
BackgroundIn patients with severe hemophilia A prolonged bleeding may occur even in cases of minor trauma or surgery.
ObjectiveTo investigate the...
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Adult People with Hemophilia A Have Low Annualized Bleeding Rate, However the Arthropathy Remains a Burden: A Retrospective Cohort Study
Congenital Hemophilia A is a complex disease to treat, especially in places without access to hemophilia treatment centers (HTCs). The primary aim of...
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Laparoscopic hepatectomy for hepatocellular carcinoma in patients with hemophilia A and B: a report of two cases
Hepatocellular carcinoma (HCC) is a life-threatening complication of hemophilia. Reports of patients with hemophilia undergoing hepatectomy for HCC...
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Comparison Pharmacokinetic Dosing Tools in Hemophilia A Children
Prophylaxis is the gold standard for the management of hemophilia A patients. It has been shown that prophylaxis regulated with pharmacokinetic (PK)...
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Understanding treatment burden in hemophilia: development and validation of the Hemophilia Treatment Experience Measure (Hemo-TEM)
BackgroundTo capture the broad range of treatment burden issues experienced by adolescent and adult people with hemophilia (PWH), the Hemophilia...
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Successful initiation of hemodialysis for a hemophilia A patient with factor VIII inhibitor: a case report and literature review
We report the first case of hemophilia A with factor VIII (FVIII) inhibitor who received hemodialysis via an arteriovenous (AV) fistula. Hemophilia A...
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A child diagnosed with severe hemophilia A presenting with nephrotic syndrome: a case report
BackgroundNephrotic syndrome occurring as a complication of immune tolerance therapy for inhibitors in hemophilia B is well recognized. It is also...
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Non-viral and viral delivery systems for hemophilia A therapy: recent development and prospects
Recent advancements have focused on enhancing factor VIII half-life and refining its delivery methods, despite the well-established knowledge that...
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Acquired Hemophilia A: Rare Cause of Upper Airway Hematoma and a Literature Review
Background: Acquired hemophilia A (AHA) is a rare blood disorder with high morbidity and even mortality as severe bleeding can occur in up to 90% of...
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Depression and anxiety among hemophilia patients enrolled in clinical trials: a multi-center cohort study
Hemophilia patients enrolled in clinical trials often exhibit various physical and psychological symptoms. However, little is known about anxiety and...
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Hemophilia patients: are they naturally anticoagulated?
Hemophilia is an X-linked bleeding disorder, characterized by low plasma levels of coagulation factor VIII (FVIII) (hemophilia A) or FIX (hemophilia...
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Successful treatment of Henoch-Schönlein purpura-associated hematochezia in a child with hemophilia A: a case report
BackgroundHenoch-Schönlein purpura (HSP) is a common form of immunological vasculitis in children. Hemophilia A is a genetic disorder and...
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Internal carotid artery dissection in a patient with hemophilia A: a case report and literature review
Spontaneous cervical artery dissection (sCeAD) is the most common cause of ischemic stroke at a young age, but its pathogenetic mechanism and risk...