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Hairy Cell Leukemia: Where Are We in 2023?
Purpose of ReviewThis article summarizes the current state of knowledge of hairy cell leukemia (HCL) regarding presentation, diagnosis, therapy, and...
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Genetic Variations in Hairy Cell Leukemia with Brain Involvement: Case Report
Hairy cell leukemia (HCL) is an infrequent neoplasm of mature B cells with rare neurologic involvement. These patients typically present with...
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Advances in the Treatment of Hairy Cell Leukemia Variant
Hairy cell leukemia variant (HCL-V) is a rare B cell lymphoproliferative disorder with a clinical-pathological distinction from the classic form of...
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BRAF inhibitor treatment of classical hairy cell leukemia allows successful vaccination against SARS-CoV-2
In classical hairy cell leukemia (HCL), standard treatments including purine analogs achieve a durable response (up to 90%), but lead to severe...
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Hairy cell leukemia: a specific 17-gene expression signature points to new targets for therapy
BackgroundHairy cell leukemia (HCL) is a rare chronic B cell malignancy, characterized by infiltration of bone marrow, blood and spleen by typical...
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Hairy Cell Leukemia (HCL) and HCL Variant: Updates and Spotlights on Therapeutic Advances
Purpose of ReviewThis article aims to bring an update on the recent discoveries in hairy cell leukemia (HCL), especially findings in pathophysiology...
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Purine nucleoside analogs plus rituximab are an effective treatment choice for hairy cell leukemia-variant
Both characteristics and optimal treatment strategy for hairy cell leukemia-variant (HCL-v) remain elusive due to its rarity. We retrospectively...
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Long-term outcomes of elderly hairy cell leukemia patients treated with cladribine
Hairy cell leukemia (HCL) is a rare hematologic disorder characterized by pancytopenia and splenomegaly for which a single course of cladribine is...
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Skin changes in hairy cell leukemia
Skin lesions have been reported in about 10–12% of hairy cell leukemia (HCL) patients. Most are etiologically related to autoimmune or infectious...
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Hairy cell leukemia and COVID-19 adaptation of treatment guidelines
Standard treatment options in classic HCL (cHCL) result in high response rates and near normal life expectancy. However, the disease itself and the...
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B-cell prolymphocytic leukemia: an enduring bona fide entity
B-cell prolymphocytic leukemia (B-PLL) was recognized as a distinct entity in the fourth edition of the World Health Organization (WHO)...
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Attack of the clones: a T-cell population resembling adult T-cell leukemia/lymphoma, and large granular lymphocytosis, in an HTLV-2-infected patient
The HTLV-1 and HTLV-2 viruses, though closely genetically related, have divergent clinical impact: HTLV-1 has been causally linked with adult T-cell...
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Biology and Treatment of Hairy Cell Leukemia
Despite its rarity, hairy cell leukemia (HCL) remains a fascinating disease and the physiopathology is becoming more and more understood. The...
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The Utility of CD43 and CD200 in Differentiating Chronic Lymphocytic Leukemia from Other Mature B-Cell Neoplasms: A Cross Sectional Study
To evaluate the utility of CD43 and CD200 in differentiating chronic lymphocytic leukemia (CLL) from other mature B-cell neoplasms. This was a...