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Biomarkers of Age-Related Frailty and Frailty Related to Diseases: An Exploratory, Cross-Sectional Analysis from the MAPT Study
BackgroundFrailty may in most cases result from two main causes: the aging process (age-related frailty) and diseases (evolving chronic conditions or...
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Association of age-related eye diseases with cognitive frailty in older adults: a population-based study
BackgroundAge-related eye diseases and cognitive frailty (CF) are both important predictors of adverse health outcomes in older adults, however,...
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Dysphagia is closely related to frailty in mild-to-moderate Alzheimer’s disease
IntroductionPhysical phenotype and the cumulative deficit model are two well-known concepts of frailty. One of the main components of frailty is loss...
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Assessing Frailty in Gastrointestinal Cancer: Two Diseases in One?
Purposeof ReviewThis review examines the challenges of treating gastrointestinal cancer in the aging population, focusing on the importance of...
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Physical frailty is related to oxidative stress through thiol/disulfide homeostasis parameters
AimTo evaluate relationship between frailty and oxidative stress through thiol/disulfide homeostasis parameters [Native thiol (NT), total thiol (TT),...
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Self-Reported Oral Diseases and Their Association with the Frailty index among Older Japanese People: Four-Year Follow-Up
BackgroundOral health is a relevant component for overall health. Oral disease onset at an early age and may harm several health dimensions,...
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Association between physical performance during sit-to-stand motion and frailty in older adults with cardiometabolic diseases: a cross-sectional, longitudinal study
BackgroundAlthough physical performance tests of the lower extremities are used to assess sarcopenia and frailty, little is known about the...
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Immunosenescence, Inflammaging, and Frailty: Role of Myeloid Cells in Age-Related Diseases
The immune system is the central regulator of tissue homeostasis, ensuring tissue regeneration and protection against both pathogens and the...
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Intraoperative electroencephalogram features related to frailty in older patients: an exploratory prospective observational study
Frailty is an independent risk factor for the increased incidence of postoperative delirium (POD). To date, the effect of frailty on intraoperative...
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Multimorbidity and frailty are associated with poorer SARS-CoV-2-related outcomes: systematic review of population-based studies
BackgroundEstimating the risks and impacts of COVID-19 for different health groups at the population level is essential for orienting public health...
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Frailty-Related Factors among Women Living with and without HIV Aged 40 Years and Older. The Women’s Interagency HIV Study
BackgroundFrailty is a clinical, geriatric syndrome linked to disability and mortality; and may be associated with a variety of factors among...
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Can We Distinguish Age-Related Frailty from Frailty Related to Diseases? Data from the MAPT Study
BackgroundNo study has tried to distinguish subjects that become frail due to diseases (frailty related to diseases) or in the absence of specific...
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Serum biomarkers related to frailty predict negative outcomes in older adults with hip fracture
PurposeHip fracture is a public health problem worldwide. Traditional prognostic models do not include blood biomarkers, such as those obtained by...
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Inflammaging and Frailty in Immune-Mediated Rheumatic Diseases: How to Address and Score the Issue
Frailty is a new concept in rheumatology that can help identify people more likely to have less favorable outcomes. Sarcopenia and inflammaging can...
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Relationship of Frailty, Nutritional Status and Oral Health-Related Quality of Life in Mexico City Nursing Home Residents
BackgroundWe aimed to identify the association among nutritional status, Oral Health-Related Quality of Life (OHRQoL) and frailty, and to estimate...
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Frailty Trajectories and Its Associated Factors in Japanese Older Adults
BackgroundAssociated factors for frailty development according to age group remain unclear.
ObjectivesTo identify frailty score trajectories among...
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Assessing causality between inflammatory bowel diseases with frailty index and sarcopenia: a bidirectional Mendelian randomization study
BackgroundPrevious studies have found that frailty and sarcopenia are commonly diagnosed in inflammatory bowel disease (IBD) patients, indicating an...
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Incorporating frailty to address the key challenges to geriatric economic evaluation
BackgroundThe multidimensional and dynamically complex process of ageing presents key challenges to economic evaluation of geriatric interventions,...
