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Global epidemiology of acute coronary syndromes
This Review provides an epidemiological overview of global mortality from acute coronary syndromes (ACS). Across the regions of the world where data...
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Lipid Lowering Drugs in Acute Coronary Syndromes (ACS)
Purpose of ReviewThe purpose of this review is to critically discuss whether more aggressive lipid-lowering strategies are needed in patients with...
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Acute Coronary Syndromes Among Patients with Prior Coronary Artery Bypass Surgery
Purpose of ReviewAcute coronary syndromes (ACS) often occur in individuals with prior coronary artery bypass graft surgery (CABG). Our goal was to...
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Management Considerations for Acute Coronary Syndromes in Chronic Kidney Disease
Purpose of ReviewPropensity of patients with chronic kidney disease (CKD) to adverse outcomes of acute coronary syndromes (ACS) derives, in part,...
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Safety and Efficacy of Cangrelor in Acute Coronary Syndromes: A Systematic Review and Network Meta-Analysis
IntroductionCangrelor is a potent intravenous non-thienopyridine P2Y12 inhibitor. We conducted a network meta-analysis to study the efficacy and...
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Drug-Coated Balloon in Acute Coronary Syndromes: Ready for the Prime Time?
Purpose of ReviewAcute coronary syndromes (ACS) are a major global health concern. Percutaneous coronary intervention (PCI) with new-generation...
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De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an international expert panel on coronary thrombosis
Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes undergoing percutaneous coronary intervention comprises...
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The Impact of CYP2C19 Genotype on the Platelet Reactivity Index (PRI) among Chronic Coronary Syndromes (CCS) Patients Undergoing Percutaneous Coronary Intervention (PCI): Affectability of Rapid Genetic Testing
BackgroundIn the Asian population, the presence of the CYP2C19 loss-of-function (LOF) allele is a known genetic variation. This allele is associated...
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Association of the triglyceride glucose-body mass index with the extent of coronary artery disease in patients with acute coronary syndromes
BackgroundStudies have shown that insulin resistance is strongly associated with the development of cardiovascular disease, and the triglyceride...
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Layered plaque and plaque volume in patients with acute coronary syndromes
BackgroundLayered plaque is a signature of previous subclinical plaque destabilization and healing. Following plaque disruption, thrombus becomes...
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GRACE scores or high-sensitivity troponin for timing of coronary angiography in non-ST-elevation acute coronary syndromes
BackgroundThe GRACE risk score is generically recommended by guidelines for timing of invasive coronary angiography without stating which score...
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Uric acid plasma levels are associated with C-reactive protein concentrations and the extent of coronary artery lesions in patients with acute coronary syndromes
Many studies have pointed out that inflammation plays a pivotal role in pathophysiology of acute coronary syndromes (ACS) because several...
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Quantitative flow ratio or angiography for the assessment of non-culprit lesions in acute coronary syndromes, a randomized trial
BackgroundPatients undergoing percutaneous coronary intervention for acute coronary syndromes often have multivessel disease (MVD). Quantitative flow...
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Incidence and pattern of urgent revascularization in acute coronary syndromes treated with ticagrelor or prasugrel
BackgroundThe ISAR-REACT 5 trial compared the efficacy and safety of ticagrelor and prasugrel in patients with ACS managed invasively. The present...
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Prognostic impact of fractional flow reserve measurements in patients with acute coronary syndromes: a subanalysis of the FLORIDA study
Randomized trials suggest benefits for fractional flow reserve (FFR)-guided vs. angiography-guided treatment strategies in well-defined and selected...
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Efficacy and safety of immune checkpoint inhibitors in solid tumor patients combined with chronic coronary syndromes or its risk factor: a nationwide multicenter cohort study
BackgroundAlthough, immune checkpoint inhibitors (ICIs) have been widely applied in the therapy of malignant tumors, the efficacy and safety of ICIs...
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The sham effect of invasive interventions in chronic coronary syndromes: a systematic review and meta-analysis
BackgroundSome patients with chronic coronary syndromes undergo invasive procedures but the efficacy of such interventions remains to be robustly...
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Correlation between Characteristics of Coronary Plaque and Chinese Medicine Syndromes of Coronary Heart Disease: A Cross-Sectional Study Analysed by Intravascular Ultrasound
ObjectiveTo analyse the correlation between the characteristics of coronary plaque in coronary heart disease (CHD) patients with phlegm-blood stasis...
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Diagnostic performance of quantitative flow ratio in non-ST elevation acute coronary syndromes in comparison to non-hyperemic pressure ratios: a prospective study
Quantitative flow ratio (QFR) is a new angiography-based coronary physiology tool aimed to evaluate functional relevance of intermediate coronary...
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Radial Artery Access for Acute Coronary Syndromes: a Review of Current Evidence
Purpose of ReviewTo review the evidence supporting the use of transradial access (TRA) for percutaneous coronary intervention (PCI) in acute coronary...